27 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	ap2a2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (944 aa)
	LOC108280768	Cullin-1; Belongs to the cullin family. (777 aa)
	EEF1A1	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	igf1r	Tyrosine-protein kinase receptor. (1395 aa)
	rpl8	60S ribosomal protein L8; Component of the large ribosomal subunit. (257 aa)
	LOC108258313	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	LOC108271091	Tyrosine-protein kinase receptor. (1357 aa)
	LOC108258496	Protein CYR61-like isoform X1. (371 aa)
	megf11	Multiple epidermal growth factor-like domains protein 11 isoform X2. (1069 aa)
	rab11a	RAB11A, member RAS oncogene family. (225 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (201 aa)
	LOC100526699	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	ctsd	Cathepsin D precursor; Belongs to the peptidase A1 family. (410 aa)
	adcy7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1106 aa)
	ctsb	Cathepsin Ba; Belongs to the peptidase C1 family. (345 aa)
	ccne1	G1/S-specific cyclin-E1 isoform X2; Belongs to the cyclin family. (404 aa)
	LOC108256043	Growth arrest-specific protein 1-like. (267 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	LOC108276238	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC108260269	Growth arrest-specific protein 1-like. (283 aa)
	ap2a1	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (946 aa)
	rab25	RAB25, member RAS oncogene family. (217 aa)
	csk	Tyrosine-protein kinase. (449 aa)
	cul1	Cullin 1. (861 aa)
	LOC108256503	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (458 aa)
	egfr	Receptor protein-tyrosine kinase. (1199 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSK	LOC108256043	ENSIPUP00000015381	ENSIPUP00000017804	Tyrosine-protein kinase.	Growth arrest-specific protein 1-like.	0.440
CSK	LOC108258496	ENSIPUP00000015381	ENSIPUP00000032094	Tyrosine-protein kinase.	Protein CYR61-like isoform X1.	0.552
CSK	LOC108260269	ENSIPUP00000015381	ENSIPUP00000009873	Tyrosine-protein kinase.	Growth arrest-specific protein 1-like.	0.440
CSK	adcy7	ENSIPUP00000015381	ENSIPUP00000023683	Tyrosine-protein kinase.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.440
CSK	ap2a1	ENSIPUP00000015381	ENSIPUP00000009719	Tyrosine-protein kinase.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.579
CSK	ap2a2	ENSIPUP00000015381	ENSIPUP00000026518	Tyrosine-protein kinase.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.582
CSK	ccne1	ENSIPUP00000015381	ENSIPUP00000020267	Tyrosine-protein kinase.	G1/S-specific cyclin-E1 isoform X2; Belongs to the cyclin family.	0.589
CSK	egfr	ENSIPUP00000015381	ENSIPUP00000015198	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.551
CSK	megf11	ENSIPUP00000015381	ENSIPUP00000031857	Tyrosine-protein kinase.	Multiple epidermal growth factor-like domains protein 11 isoform X2.	0.595
CSK	ppp2ca	ENSIPUP00000015381	ENSIPUP00000010003	Tyrosine-protein kinase.	Serine/threonine-protein phosphatase.	0.677
CSK	rab11a	ENSIPUP00000015381	ENSIPUP00000031845	Tyrosine-protein kinase.	RAB11A, member RAS oncogene family.	0.506
CSK	rab25	ENSIPUP00000015381	ENSIPUP00000008921	Tyrosine-protein kinase.	RAB25, member RAS oncogene family.	0.502
CSK	skp1	ENSIPUP00000015381	ENSIPUP00000030698	Tyrosine-protein kinase.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.545
EEF1A1	rpl8	ENSIPUP00000034828	ENSIPUP00000034487	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	60S ribosomal protein L8; Component of the large ribosomal subunit.	0.704
LOC100526699	rpl8	ENSIPUP00000029480	ENSIPUP00000034487	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	60S ribosomal protein L8; Component of the large ribosomal subunit.	0.730
LOC108256043	CSK	ENSIPUP00000017804	ENSIPUP00000015381	Growth arrest-specific protein 1-like.	Tyrosine-protein kinase.	0.440
LOC108256043	LOC108258496	ENSIPUP00000017804	ENSIPUP00000032094	Growth arrest-specific protein 1-like.	Protein CYR61-like isoform X1.	0.518
LOC108256043	LOC108260269	ENSIPUP00000017804	ENSIPUP00000009873	Growth arrest-specific protein 1-like.	Growth arrest-specific protein 1-like.	0.904
LOC108256043	ap2a1	ENSIPUP00000017804	ENSIPUP00000009719	Growth arrest-specific protein 1-like.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.519
LOC108256043	ap2a2	ENSIPUP00000017804	ENSIPUP00000026518	Growth arrest-specific protein 1-like.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.519