10 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
	nod2	Nucleotide-binding oligomerization domain-containing protein 2. (981 aa)
	il10	Interleukin-10. (223 aa)
	tlr3	Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family. (905 aa)
	tlr2	Toll-like receptor 2. (790 aa)
	nod1	Nucleotide-binding oligomerization domain-containing protein 1. (946 aa)
	tlr-5	Toll-like receptor 5 precursor. (647 aa)
	TLR5	Toll-like receptor 5; Belongs to the Toll-like receptor family. (880 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (279 aa)
	LOC100335032	Myeloperoxidase isoform X1. (777 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TLR5	il10	ENSIPUP00000016467	ENSIPUP00000035880	Toll-like receptor 5; Belongs to the Toll-like receptor family.	Interleukin-10.	0.556
TLR5	myd88	ENSIPUP00000016467	ENSIPUP00000018002	Toll-like receptor 5; Belongs to the Toll-like receptor family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.983
TLR5	tlr-5	ENSIPUP00000016467	ENSIPUP00000016445	Toll-like receptor 5; Belongs to the Toll-like receptor family.	Toll-like receptor 5 precursor.	0.900
TLR5	tlr2	ENSIPUP00000016467	ENSIPUP00000001951	Toll-like receptor 5; Belongs to the Toll-like receptor family.	Toll-like receptor 2.	0.463
TLR5	traf6	ENSIPUP00000016467	ENSIPUP00000032978	Toll-like receptor 5; Belongs to the Toll-like receptor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.714
il10	TLR5	ENSIPUP00000035880	ENSIPUP00000016467	Interleukin-10.	Toll-like receptor 5; Belongs to the Toll-like receptor family.	0.556
il10	myd88	ENSIPUP00000035880	ENSIPUP00000018002	Interleukin-10.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.789
il10	nod1	ENSIPUP00000035880	ENSIPUP00000012839	Interleukin-10.	Nucleotide-binding oligomerization domain-containing protein 1.	0.434
il10	tlr-5	ENSIPUP00000035880	ENSIPUP00000016445	Interleukin-10.	Toll-like receptor 5 precursor.	0.556
il10	tlr2	ENSIPUP00000035880	ENSIPUP00000001951	Interleukin-10.	Toll-like receptor 2.	0.722
il10	tlr3	ENSIPUP00000035880	ENSIPUP00000001661	Interleukin-10.	Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family.	0.622
il10	traf6	ENSIPUP00000035880	ENSIPUP00000032978	Interleukin-10.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.426
myd88	TLR5	ENSIPUP00000018002	ENSIPUP00000016467	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-like receptor 5; Belongs to the Toll-like receptor family.	0.983
myd88	il10	ENSIPUP00000018002	ENSIPUP00000035880	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Interleukin-10.	0.789
myd88	nod1	ENSIPUP00000018002	ENSIPUP00000012839	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Nucleotide-binding oligomerization domain-containing protein 1.	0.626
myd88	nod2	ENSIPUP00000018002	ENSIPUP00000023997	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Nucleotide-binding oligomerization domain-containing protein 2.	0.607
myd88	tlr-5	ENSIPUP00000018002	ENSIPUP00000016445	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-like receptor 5 precursor.	0.984
myd88	tlr2	ENSIPUP00000018002	ENSIPUP00000001951	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-like receptor 2.	0.989
myd88	tlr3	ENSIPUP00000018002	ENSIPUP00000001661	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-like receptor 3 precursor; Belongs to the Toll-like receptor family.	0.917
myd88	traf6	ENSIPUP00000018002	ENSIPUP00000032978	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.998