STRINGSTRING
gpx4 gpx4 LOC100305036 LOC100305036 LOC108259599 LOC108259599 BAX BAX bax bax gpx1 gpx1 GPX2 GPX2 gsx1 gsx1 gpx8 gpx8 LOC108255192 LOC108255192 sod2 sod2 pcna pcna gpx7 gpx7 LOC108273566 LOC108273566 gpx3 gpx3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gpx4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (112 aa)
LOC100305036Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...] (649 aa)
LOC108259599Apoptosis regulator BAX-like isoform X1. (203 aa)
BAXBCL2 associated X, apoptosis regulator. (176 aa)
baxApoptosis regulator BAX. (189 aa)
gpx1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
gsx1GS homeobox 1. (257 aa)
gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
LOC108255192Glutathione peroxidase; Belongs to the glutathione peroxidase family. (178 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (297 aa)
gpx7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
LOC108273566Glutathione peroxidase; Belongs to the glutathione peroxidase family. (137 aa)
gpx3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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