17 items (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stim1	Stromal interaction molecule 1 isoform X1. (666 aa)
	LOC100304635	Caspase 8 isoform X1; Belongs to the peptidase C14A family. (371 aa)
	LOC108273129	Caspase-8-like; Belongs to the peptidase C14A family. (353 aa)
	ifng1	Interferon gamma 2a precursor. (178 aa)
	mcu	Calcium uniporter protein, mitochondrial. (457 aa)
	ecsit	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1. (452 aa)
	LOC108266930	Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (525 aa)
	casp3	Caspase-3 isoform X1; Belongs to the peptidase C14A family. (285 aa)
	orai1	Calcium release-activated calcium channel protein 1. (236 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
	LOC108260860	Caspase-3-like; Belongs to the peptidase C14A family. (287 aa)
	il10	Interleukin-10. (223 aa)
	LOC108279869	Tyrosine 3-monooxygenase-like. (465 aa)
	LOC108276842	Calcium release-activated calcium channel protein 1. (224 aa)
	tlr2	Toll-like receptor 2. (790 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (279 aa)
	LOC108273098	Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (493 aa)

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100304635	LOC108260860	ENSIPUP00000020451	ENSIPUP00000034973	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	Caspase-3-like; Belongs to the peptidase C14A family.	0.948
LOC100304635	casp3	ENSIPUP00000020451	ENSIPUP00000030411	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	Caspase-3 isoform X1; Belongs to the peptidase C14A family.	0.947
LOC100304635	myd88	ENSIPUP00000020451	ENSIPUP00000018002	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.499
LOC100304635	traf6	ENSIPUP00000020451	ENSIPUP00000032978	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.554
LOC108260860	LOC100304635	ENSIPUP00000034973	ENSIPUP00000020451	Caspase-3-like; Belongs to the peptidase C14A family.	Caspase 8 isoform X1; Belongs to the peptidase C14A family.	0.948
LOC108260860	LOC108266930	ENSIPUP00000034973	ENSIPUP00000028592	Caspase-3-like; Belongs to the peptidase C14A family.	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	0.963
LOC108260860	LOC108273098	ENSIPUP00000034973	ENSIPUP00000020296	Caspase-3-like; Belongs to the peptidase C14A family.	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	0.963
LOC108260860	LOC108273129	ENSIPUP00000034973	ENSIPUP00000022736	Caspase-3-like; Belongs to the peptidase C14A family.	Caspase-8-like; Belongs to the peptidase C14A family.	0.916
LOC108260860	casp3	ENSIPUP00000034973	ENSIPUP00000030411	Caspase-3-like; Belongs to the peptidase C14A family.	Caspase-3 isoform X1; Belongs to the peptidase C14A family.	0.902
LOC108266930	LOC108260860	ENSIPUP00000028592	ENSIPUP00000034973	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	Caspase-3-like; Belongs to the peptidase C14A family.	0.963
LOC108266930	casp3	ENSIPUP00000028592	ENSIPUP00000030411	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	Caspase-3 isoform X1; Belongs to the peptidase C14A family.	0.963
LOC108266930	myd88	ENSIPUP00000028592	ENSIPUP00000018002	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.538
LOC108266930	traf6	ENSIPUP00000028592	ENSIPUP00000032978	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.669
LOC108273098	LOC108260860	ENSIPUP00000020296	ENSIPUP00000034973	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	Caspase-3-like; Belongs to the peptidase C14A family.	0.963
LOC108273098	casp3	ENSIPUP00000020296	ENSIPUP00000030411	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	Caspase-3 isoform X1; Belongs to the peptidase C14A family.	0.964
LOC108273098	traf6	ENSIPUP00000020296	ENSIPUP00000032978	Caspase-8-like isoform X1; Belongs to the peptidase C14A family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.669
LOC108273129	LOC108260860	ENSIPUP00000022736	ENSIPUP00000034973	Caspase-8-like; Belongs to the peptidase C14A family.	Caspase-3-like; Belongs to the peptidase C14A family.	0.916
LOC108273129	casp3	ENSIPUP00000022736	ENSIPUP00000030411	Caspase-8-like; Belongs to the peptidase C14A family.	Caspase-3 isoform X1; Belongs to the peptidase C14A family.	0.917
LOC108273129	myd88	ENSIPUP00000022736	ENSIPUP00000018002	Caspase-8-like; Belongs to the peptidase C14A family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.405
LOC108276842	mcu	ENSIPUP00000036965	ENSIPUP00000026163	Calcium release-activated calcium channel protein 1.	Calcium uniporter protein, mitochondrial.	0.556