STRINGSTRING
LOC108266930 LOC108266930 LOC108273362 LOC108273362 hdac7 hdac7 bax bax BAX BAX LOC108273129 LOC108273129 nos2 nos2 casp9 casp9 esr1 esr1 LOC108277518 LOC108277518 LOC108272688 LOC108272688 LOC108259599 LOC108259599 LOC100304635 LOC100304635 LOC108273098 LOC108273098 hdac3 hdac3 LOC108267470 LOC108267470 endog endog hdac5 hdac5 hdac4 hdac4 LOC108267799 LOC108267799 bcl2 bcl2 nos1 nos1 casp3 casp3 LOC108278882 LOC108278882 got2 got2 LOC108260860 LOC108260860 LOC108267638 LOC108267638 HDAC2 HDAC2 hdac8 hdac8 got1 got1 polb polb LOC108264160 LOC108264160 idh1 idh1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108266930Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (525 aa)
LOC108273362Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
hdac7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (937 aa)
baxApoptosis regulator BAX. (189 aa)
BAXBCL2 associated X, apoptosis regulator. (176 aa)
LOC108273129Caspase-8-like; Belongs to the peptidase C14A family. (353 aa)
nos2Nitric oxide synthase; Produces nitric oxide (NO). (1080 aa)
casp9Caspase-9 isoform X2; Belongs to the peptidase C14A family. (432 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (617 aa)
LOC108277518Nitric oxide synthase; Produces nitric oxide (NO). (1038 aa)
LOC108272688Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (511 aa)
LOC108259599Apoptosis regulator BAX-like isoform X1. (203 aa)
LOC100304635Caspase 8 isoform X1; Belongs to the peptidase C14A family. (371 aa)
LOC108273098Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (493 aa)
hdac3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
LOC108267470Apoptosis regulator Bcl-2-like. (204 aa)
endogEndonuclease. (305 aa)
hdac5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1031 aa)
hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1043 aa)
LOC108267799Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (630 aa)
bcl2Apoptosis regulator Bcl-2. (204 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1412 aa)
casp3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (285 aa)
LOC108278882Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1181 aa)
got2Aspartate aminotransferase. (428 aa)
LOC108260860Caspase-3-like; Belongs to the peptidase C14A family. (287 aa)
LOC108267638Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1180 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (544 aa)
hdac8Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (407 aa)
got1Aspartate aminotransferase. (411 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa)
LOC108264160Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (84 aa)
idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (415 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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