STRINGSTRING
mcm4 mcm4 pcna pcna espl1 espl1 cdk1 cdk1 cdca5 cdca5 pds5b pds5b smc3 smc3 rec8 rec8 nipbl nipbl ctcf ctcf mcm7 mcm7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mcm4DNA helicase; Belongs to the MCM family. (845 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (297 aa)
espl1Separin. (2166 aa)
cdk1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (302 aa)
cdca5Sororin. (262 aa)
pds5bSister chromatid cohesion protein PDS5 homolog B. (1413 aa)
smc3Structural maintenance of chromosomes protein. (1217 aa)
rec8Meiotic recombination protein REC8 homolog isoform X1. (577 aa)
nipblNipped-B protein. (2641 aa)
ctcfTranscriptional repressor CTCF isoform X1. (865 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (722 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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