STRINGSTRING
LOC108265013 LOC108265013 LOC108263675 LOC108263675 LOC108264442 LOC108264442 xiap xiap LOC108269206 LOC108269206 LOC108264340 LOC108264340 birc2 birc2 ern2 ern2 LOC108258691 LOC108258691 LOC108258364 LOC108258364 LOC108263800 LOC108263800 ctsw ctsw ctsc ctsc itpr3 itpr3 lmnb1 lmnb1 LOC108259510 LOC108259510 pik3ca pik3ca parp4 parp4 LOC108256914 LOC108256914 LOC108275608 LOC108275608 LOC108274827 LOC108274827 pik3cd pik3cd LOC108267538 LOC108267538 ctso ctso LOC108274959 LOC108274959 LOC108278540 LOC108278540 LOC108278539 LOC108278539 bcl2 bcl2 LOC108258562 LOC108258562 tradd tradd daxx daxx LOC108279085 LOC108279085 LOC108265838 LOC108265838 LOC108259077 LOC108259077 LOC108255825 LOC108255825 pik3r3 pik3r3 LOC108263241 LOC108263241 hras hras lmna lmna ntrk1 ntrk1 catk catk ctss ctss LOC108268142 LOC108268142 dffb dffb LOC108279174 LOC108279174 LOC108280779 LOC108280779 LOC108269548 LOC108269548 gadd45b gadd45b tnfrsf1a tnfrsf1a LOC108278925 LOC108278925 LOC108278924 LOC108278924 atm atm LOC108268328 LOC108268328 LOC108280679 LOC108280679 LOC108280700 LOC108280700 casp2 casp2 LOC108280715 LOC108280715 LOC108280710 LOC108280710 LOC108280734 LOC108280734 LOC108280723 LOC108280723 LOC108280689 LOC108280689 LOC108275580 LOC108275580 pidd1 pidd1 akt3 akt3 pik3cb pik3cb LOC108261837 LOC108261837 map3k5 map3k5 endog endog LOC108265896 LOC108265896 dffa dffa LOC108267277 LOC108267277 LOC108264960 LOC108264960 BIRC5 BIRC5 nras nras LOC108266769 LOC108266769 ctsz ctsz catl catl LOC108269856 LOC108269856 LOC108269855 LOC108269855 ern1 ern1 raf1 raf1 LOC108261848 LOC108261848 LOC108260779 LOC108260779 LOC108272203 LOC108272203 ctsl ctsl faslg faslg LOC108267470 LOC108267470 jun jun LOC108259403 LOC108259403 nfkbia nfkbia LOC108273468 LOC108273468 LOC100304651 LOC100304651 LOC108267046 LOC108267046 LOC108259406 LOC108259406 LOC108259420 LOC108259420 LOC108255233 LOC108255233 LOC108257020 LOC108257020 LOC108255063 LOC108255063 LOC108259404 LOC108259404 LOC108267848 LOC108267848 ikbkg ikbkg bcl2l1 bcl2l1 LOC108274025 LOC108274025 LOC108273098 LOC108273098 LOC100304635 LOC100304635 LOC108280806 LOC108280806 LOC108276493 LOC108276493 fadd fadd LOC108259599 LOC108259599 LOC108276487 LOC108276487 LOC108270970 LOC108270970 ctsb ctsb LOC108258222 LOC108258222 LOC108273465 LOC108273465 LOC108273129 LOC108273129 parp2 parp2 LOC108259239 LOC108259239 bax bax LOC108263943 LOC108263943 ptpn13 ptpn13 LOC108278211 LOC108278211 LOC108278438 LOC108278438 nfkb1 nfkb1 tnf tnf LOC108260991 LOC108260991 LOC108255380 LOC108255380 traf2 traf2 LOC108256206 LOC108256206 atf4 atf4 LOC108274750 LOC108274750 LOC108280169 LOC108280169 pik3r1 pik3r1 casp7 casp7 actb actb apaf1 apaf1 LOC108278350 LOC108278350 itpr2 itpr2 LOC108259907 LOC108259907 ctsd ctsd bcl2l11 bcl2l11 LOC108260086 LOC108260086 parp3 parp3 LOC108276324 LOC108276324 LOC108273362 LOC108273362 mp2k2 mp2k2 LOC108266930 LOC108266930 LOC108257355 LOC108257355 casp9 casp9 akt1 akt1 LOC108267915 LOC108267915 mapk9 mapk9 parp1 parp1 mapk1 mapk1 casp3 casp3 bad bad eif2s1 eif2s1 chuk chuk LOC108278958 LOC108278958 tp53 tp53 map2k1 map2k1 LOC108264936 LOC108264936 itpr1 itpr1 LOC108255678 LOC108255678 LOC108275942 LOC108275942 LOC108274831 LOC108274831 LOC108274846 LOC108274846 LOC108259582 LOC108259582 catd catd LOC108264602 LOC108264602 LOC108258948 LOC108258948 LOC108270534 LOC108270534 LOC108260860 LOC108260860 ngf ngf LOC108270103 LOC108270103 LOC108259889 LOC108259889 ctsh ctsh ddit3 ddit3 LOC108278451 LOC108278451 ikbkb ikbkb lmnb2 lmnb2 LOC108270686 LOC108270686
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108265013Perforin-1-like. (519 aa)
LOC108263675Mitogen-activated protein kinase. (439 aa)
LOC1082644423-phosphoinositide-dependent protein kinase 1-like isoform X1. (537 aa)
xiapE3 ubiquitin-protein ligase XIAP isoform X2. (437 aa)
LOC108269206E3 ubiquitin-protein ligase XIAP-like isoform X1. (386 aa)
LOC108264340Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa)
birc2Baculoviral IAP repeat-containing protein 2 isoform X1. (616 aa)
ern2Serine/threonine-protein kinase/endoribonuclease IRE2 isoform X1. (929 aa)
LOC108258691Actin, cytoplasmic 1. (375 aa)
LOC108258364Cytokine receptor common subunit beta-like isoform X2. (726 aa)
LOC108263800Caspase-6-like; Belongs to the peptidase C14A family. (306 aa)
ctswCathepsin F; Belongs to the peptidase C1 family. (470 aa)
ctscDipeptidyl peptidase 1; Belongs to the peptidase C1 family. (452 aa)
itpr3Inositol 1,4,5-trisphosphate receptor type 3. (2697 aa)
lmnb1lamin-B1 isoform X2; Belongs to the intermediate filament family. (618 aa)
LOC108259510CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (436 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
parp4Poly [ADP-ribose] polymerase. (1861 aa)
LOC108256914Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (464 aa)
LOC108275608Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1054 aa)
LOC108274827Cathepsin L1-like isoform X1; Belongs to the peptidase C1 family. (354 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
LOC108267538Bcl2-associated agonist of cell death-like. (145 aa)
ctsoCathepsin O; Belongs to the peptidase C1 family. (341 aa)
LOC108274959GTPase KRas isoform X1. (189 aa)
LOC108278540Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (107 aa)
LOC108278539Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (153 aa)
bcl2Apoptosis regulator Bcl-2. (204 aa)
LOC108258562Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
traddTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (332 aa)
daxxDeath domain-associated protein 6 isoform X1. (716 aa)
LOC108279085Diablo homolog, mitochondrial-like. (232 aa)
LOC108265838Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC108259077Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC108255825TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (581 aa)
pik3r3Phosphatidylinositol 3-kinase regulatory subunit alpha. (739 aa)
LOC108263241Serine protease HTRA2, mitochondrial-like. (442 aa)
hrasGTPase HRas. (189 aa)
lmnaLamin; Belongs to the intermediate filament family. (661 aa)
ntrk1Tyrosine-protein kinase receptor. (802 aa)
catkCathepsin K isoform X1; Belongs to the peptidase C1 family. (331 aa)
ctssCathepsin S precursor; Belongs to the peptidase C1 family. (329 aa)
LOC108268142Induced myeloid leukemia cell differentiation protein Mcl-1-like. (253 aa)
dffbDNAation factor subunit beta. (330 aa)
LOC108279174Tumor necrosis factor receptor superfamily member 10B-like. (432 aa)
LOC108280779Septin-5 isoform X3; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (370 aa)
LOC108269548Proto-oncogene c-Fos-like. (357 aa)
gadd45bGrowth arrest and DNA damage-inducible protein GADD45 beta. (238 aa)
tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (402 aa)
LOC108278925Septin-5-like; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (267 aa)
LOC108278924Septin-5-like isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (523 aa)
atmNon-specific serine/threonine protein kinase. (3076 aa)
LOC108268328Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC108280679Perforin-1-like. (593 aa)
LOC108280700Perforin-1-like isoform X1. (588 aa)
casp2LOW QUALITY PROTEIN: caspase-2; Belongs to the peptidase C14A family. (439 aa)
LOC108280715Perforin-1-like. (588 aa)
LOC108280710Perforin-1-like. (588 aa)
LOC108280734Perforin-1-like. (595 aa)
LOC108280723Perforin-1-like. (588 aa)
LOC108280689Perforin-1-like. (590 aa)
LOC108275580Baculoviral IAP repeat-containing protein 5.1-like isoform X2. (146 aa)
pidd1P53-induced death domain-containing protein 1. (988 aa)
akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
LOC108261837Tumor necrosis factor ligand superfamily member 10-like; Belongs to the tumor necrosis factor family. (329 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1263 aa)
endogEndonuclease. (305 aa)
LOC108265896Disabled homolog 2-interacting protein-like isoform X1. (1234 aa)
dffaDNAation factor subunit alpha. (308 aa)
LOC108267277Calpain-1 catalytic subunit-like; Belongs to the peptidase C2 family. (704 aa)
LOC108264960TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (542 aa)
BIRC5Baculoviral IAP repeat-containing protein 5-like. (190 aa)
nrasGTPase NRas. (195 aa)
LOC108266769Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (476 aa)
ctszCathepsin Z isoform X2; Belongs to the peptidase C1 family. (291 aa)
catlCathepsin L precursor; Belongs to the peptidase C1 family. (334 aa)
LOC108269856Cathepsin L1-like; Belongs to the peptidase C1 family. (334 aa)
LOC108269855Cathepsin L1-like isoform X2; Belongs to the peptidase C1 family. (359 aa)
ern1Serine/threonine-protein kinase/endoribonuclease IRE1. (1038 aa)
raf1RAF proto-oncogene serine/threonine-protein kinase isoform X2. (635 aa)
LOC108261848Caspase-6-like; Belongs to the peptidase C14A family. (165 aa)
LOC108260779Putative transcription factor p65 homolog. (601 aa)
LOC108272203Growth arrest and DNA damage-inducible protein GADD45 alpha-like. (210 aa)
ctslCathepsin L1 precursor; Belongs to the peptidase C1 family. (336 aa)
faslgTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (260 aa)
LOC108267470Apoptosis regulator Bcl-2-like. (204 aa)
junTranscription factor AP-1; Belongs to the bZIP family. (324 aa)
LOC108259403Calpain-1 catalytic subunit-like; Belongs to the peptidase C2 family. (704 aa)
nfkbiaNF-kappa-B inhibitor alpha. (320 aa)
LOC108273468Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC100304651Granzyme-like III precursor; Belongs to the peptidase S1 family. (254 aa)
LOC108267046Granzyme B(G,H)-like; Belongs to the peptidase S1 family. (254 aa)
LOC108259406Calpain-2 catalytic subunit-like; Belongs to the peptidase C2 family. (696 aa)
LOC108259420Calpain-2 catalytic subunit-like; Belongs to the peptidase C2 family. (469 aa)
LOC108255233Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (505 aa)
LOC108257020Perforin-1-like. (568 aa)
LOC108255063Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC108259404Calpain-2 catalytic subunit-like; Belongs to the peptidase C2 family. (700 aa)
LOC108267848Transcription factor AP-1-like. (275 aa)
ikbkgNF-kappa-B essential modulator. (568 aa)
bcl2l1Bcl-2-like protein 1. (242 aa)
LOC108274025Mitogen-activated protein kinase. (384 aa)
LOC108273098Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (493 aa)
LOC100304635Caspase 8 isoform X1; Belongs to the peptidase C14A family. (371 aa)
LOC108280806Growth arrest and DNA damage-inducible protein GADD45 alpha-like. (158 aa)
LOC108276493Neurotrophin-7-like; Belongs to the NGF-beta family. (211 aa)
faddFAS-associated death domain protein. (210 aa)
LOC108259599Apoptosis regulator BAX-like isoform X1. (203 aa)
LOC108276487Tumor necrosis factor receptor superfamily member 1A-like. (389 aa)
LOC108270970Apoptosis regulator BAX-like. (202 aa)
ctsbCathepsin Ba; Belongs to the peptidase C1 family. (345 aa)
LOC108258222NF-kappa-B inhibitor alpha-like. (308 aa)
LOC108273465Baculoviral IAP repeat-containing protein 5.2-like. (142 aa)
LOC108273129Caspase-8-like; Belongs to the peptidase C14A family. (353 aa)
parp2Poly [ADP-ribose] polymerase. (629 aa)
LOC108259239Mitogen-activated protein kinase kinase kinase 14-like. (854 aa)
baxApoptosis regulator BAX. (189 aa)
LOC108263943Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
ptpn13Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2354 aa)
LOC108278211Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC108278438Mitogen-activated protein kinase. (447 aa)
nfkb1Nuclear factor NF-kappa-B p105 subunit. (934 aa)
tnfTumor necrosis factor. (230 aa)
LOC108260991Proto-oncogene c-Fos-like. (101 aa)
LOC108255380Proto-oncogene c-Fos-like. (335 aa)
traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (529 aa)
LOC108256206Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (396 aa)
atf4Cyclic AMP-dependent transcription factor ATF-4. (421 aa)
LOC108274750Apoptosis regulator BAX-like. (199 aa)
LOC108280169Cathepsin Z-like; Belongs to the peptidase C1 family. (329 aa)
pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha. (728 aa)
casp7Caspase-7 isoform X1; Belongs to the peptidase C14A family. (310 aa)
actbActin, cytoplasmic 1. (377 aa)
apaf1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1236 aa)
LOC108278350Diablo homolog, mitochondrial-like. (265 aa)
itpr2Inositol 1,4,5-trisphosphate receptor type 2 isoform X3. (2683 aa)
LOC108259907Tumor necrosis factor-like; Belongs to the tumor necrosis factor family. (291 aa)
ctsdCathepsin D precursor; Belongs to the peptidase A1 family. (410 aa)
bcl2l11Bcl-2-like protein 11 isoform X2. (221 aa)
LOC108260086Transcription factor AP-1-like. (343 aa)
parp3Poly [ADP-ribose] polymerase. (524 aa)
LOC108276324RAF proto-oncogene serine/threonine-protein kinase-like. (659 aa)
LOC108273362Cytochrome C; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
mp2k2Dual specificity Mitogen-activated protein kinase kinase 2. (392 aa)
LOC108266930Caspase-8-like isoform X1; Belongs to the peptidase C14A family. (525 aa)
LOC1082573553-phosphoinositide-dependent protein kinase 1-like. (509 aa)
casp9Caspase-9 isoform X2; Belongs to the peptidase C14A family. (432 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
LOC108267915Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (394 aa)
mapk9Mitogen-activated protein kinase. (421 aa)
parp1Poly [ADP-ribose] polymerase. (1018 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
casp3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (285 aa)
badBcl2-associated agonist of cell death. (198 aa)
eif2s1Eukaryotic Translation initiation factor 2 subunit 1. (315 aa)
chukInhibitor of Nuclear factor kappa-B kinase subunit alpha. (756 aa)
LOC108278958Calpain-1 catalytic subunit-like isoform X1; Belongs to the peptidase C2 family. (739 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (376 aa)
map2k1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
LOC108264936Growth arrest and DNA damage-inducible protein GADD45 gamma-like. (161 aa)
itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X13. (2708 aa)
LOC108255678Tumor necrosis factor receptor superfamily member 10B-like isoform X1. (407 aa)
LOC108275942Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC108274831Cathepsin L1-like isoform X1; Belongs to the peptidase C1 family. (337 aa)
LOC108274846Induced myeloid leukemia cell differentiation protein Mcl-1-like. (258 aa)
LOC108259582GTPase HRas. (189 aa)
catdCathepsin D isoform X1; Belongs to the peptidase A1 family. (398 aa)
LOC108264602Uncharacterized protein LOC108264602 isoform X1. (210 aa)
LOC108258948GTPase HRas-like isoform X2. (187 aa)
LOC108270534lamin-L(III)-like isoform X1; Belongs to the intermediate filament family. (600 aa)
LOC108260860Caspase-3-like; Belongs to the peptidase C14A family. (287 aa)
ngfBeta-nerve growth factor; Belongs to the NGF-beta family. (197 aa)
LOC108270103Calpain-1 catalytic subunit-like; Belongs to the peptidase C2 family. (686 aa)
LOC108259889Disabled homolog 2-interacting protein-like isoform X1. (1226 aa)
ctshPro-cathepsin H precursor; Belongs to the peptidase C1 family. (326 aa)
ddit3DNA damage-inducible transcript 3 protein. (273 aa)
LOC108278451Proto-oncogene c-Fos-like isoform X2. (164 aa)
ikbkbInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (776 aa)
lmnb2lamin-B2; Belongs to the intermediate filament family. (586 aa)
LOC108270686Cathepsin L1-like; Belongs to the peptidase C1 family. (275 aa)
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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