(89 nodes) Centrosome maturation, and Centriole network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113584568	Serine/threonine-protein kinase PLK. (664 aa)
	LOC113568164	CDK5 regulatory subunit associated protein 2. (1558 aa)
	ENSEEEP00000001725	Uncharacterized protein. (181 aa)
	cep131	Centrosomal protein 131. (1105 aa)
	wtip	WT1 interacting protein. (665 aa)
	Cep68	Centrosomal protein 68. (650 aa)
	tubd1	Tubulin domain-containing protein; Belongs to the tubulin family. (442 aa)
	ENSEEEP00000006518	Tcp10_C domain-containing protein. (88 aa)
	ENSEEEP00000007029	Cnn_1N domain-containing protein. (178 aa)
	C2cd3	Uncharacterized protein. (310 aa)
	lrrc45	Uncharacterized protein. (676 aa)
	poc5	POC5 centriolar protein homolog (Chlamydomonas). (457 aa)
	Mapkbp1	WD_REPEATS_REGION domain-containing protein. (345 aa)
	ENSEEEP00000009159	Uncharacterized protein. (1024 aa)
	mzt1	Uncharacterized protein. (75 aa)
	bora	Bora, aurora kinase A activator. (546 aa)
	optn	CCHC NOA-type domain-containing protein. (549 aa)
	tubg1	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (449 aa)
	cep63	CEP63 domain-containing protein. (717 aa)
	LOC113578326	Ajuba LIM protein. (698 aa)
	ENSEEEP00000011804	Centrosomal protein 170Ab. (842 aa)
	ENSEEEP00000011809	FHA domain-containing protein. (94 aa)
	haus3	HAUS augmin-like complex, subunit 3. (638 aa)
	plk4	Uncharacterized protein. (923 aa)
	LOC113568384	A kinase (PRKA) anchor protein 9. (1700 aa)
	ppp1r35	PPP1R35_C domain-containing protein. (282 aa)
	haus7	Uncharacterized protein. (357 aa)
	LOC113580541	Uncharacterized protein. (222 aa)
	ENSEEEP00000014965	FHA domain-containing protein. (109 aa)
	ENSEEEP00000015339	CEP170_C domain-containing protein. (307 aa)
	ENSEEEP00000015345	FHA domain-containing protein. (114 aa)
	sdccag8	Serologically defined colon cancer antigen 8. (681 aa)
	haus4	Uncharacterized protein. (365 aa)
	LOC113567960	Uncharacterized protein. (153 aa)
	cep120	Uncharacterized protein. (982 aa)
	LOC113585558	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
	LOC113576541	Uncharacterized protein. (172 aa)
	armc7	Uncharacterized protein. (189 aa)
	fgfr1op	Uncharacterized protein. (535 aa)
	cep83	Centrosomal protein 83. (696 aa)
	rttn	Rotatin. (2137 aa)
	ENSEEEP00000020522	Uncharacterized protein. (631 aa)
	ENSEEEP00000021020	Uncharacterized protein. (199 aa)
	ENSEEEP00000021373	Centrosomal protein 72. (331 aa)
	LOC113585360	Uncharacterized protein. (555 aa)
	ccdc14	Uncharacterized protein. (485 aa)
	cep97	Centrosomal protein 97. (619 aa)
	sass6	Uncharacterized protein. (647 aa)
	haus8	Si:ch211-153a8.4. (357 aa)
	Cep350	CAP-Gly domain-containing protein. (117 aa)
	haus1	Uncharacterized protein. (273 aa)
	ENSEEEP00000025505	WD_REPEATS_REGION domain-containing protein. (325 aa)
	cenpj	Centromere protein J. (1035 aa)
	ofd1	Oral-facial-digital syndrome 1. (893 aa)
	cep76	CEP76-C2 domain-containing protein. (664 aa)
	ENSEEEP00000027249	Coiled-coil domain containing 120. (480 aa)
	arl13b	ADP-ribosylation factor-like 13b. (375 aa)
	tubgcp2	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (916 aa)
	stil	Scl/tal1 interrupting locus. (1203 aa)
	dnah10	Dynein axonemal heavy chain 10. (4608 aa)
	LOC113579647	ETAA1, ATR kinase activator. (776 aa)
	cript	Uncharacterized protein. (101 aa)
	haus2	Uncharacterized protein. (201 aa)
	haus5	Uncharacterized protein. (650 aa)
	tubgcp4	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (683 aa)
	cep89	Centrosomal protein 89. (748 aa)
	tubgcp5	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1022 aa)
	tubgcp6	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (1682 aa)
	haus6	HAUS6_N domain-containing protein. (782 aa)
	ENSEEEP00000038903	Uncharacterized protein. (389 aa)
	cep135	Uncharacterized protein. (1165 aa)
	rbm48	Uncharacterized protein. (364 aa)
	Sclt1	Uncharacterized protein. (273 aa)
	cep70	Uncharacterized protein. (621 aa)
	ENSEEEP00000044603	Uncharacterized protein. (243 aa)
	scnm1	Sodium channel modifier 1. (227 aa)
	Cep170b	FHA domain-containing protein. (97 aa)
	nedd1	Neural precursor cell expressed, developmentally down-regulated 1. (661 aa)
	ENSEEEP00000047095	Uncharacterized protein. (296 aa)
	spice1	Spindle and centriole associated protein 1. (604 aa)
	ENSEEEP00000048034	Uncharacterized protein. (293 aa)
	LIMD1	Uncharacterized protein. (618 aa)
	tubgcp3	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (883 aa)
	pcm1	Pericentriolar material 1. (1844 aa)
	cep162	Centrosomal protein 162. (1185 aa)
	ENSEEEP00000051312	Uncharacterized protein. (738 aa)
	Cntrl	Uncharacterized protein. (360 aa)
	ENSEEEP00000051438	Uncharacterized protein. (192 aa)
	cep19	Centrosomal protein 19. (212 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C2cd3	Sclt1	ENSEEEP00000007078	ENSEEEP00000043905	Uncharacterized protein.	Uncharacterized protein.	0.599
C2cd3	arl13b	ENSEEEP00000007078	ENSEEEP00000027321	Uncharacterized protein.	ADP-ribosylation factor-like 13b.	0.578
C2cd3	cep19	ENSEEEP00000007078	ENSEEEP00000051826	Uncharacterized protein.	Centrosomal protein 19.	0.422
C2cd3	cep76	ENSEEEP00000007078	ENSEEEP00000027128	Uncharacterized protein.	CEP76-C2 domain-containing protein.	0.648
C2cd3	cep83	ENSEEEP00000007078	ENSEEEP00000019975	Uncharacterized protein.	Centrosomal protein 83.	0.584
C2cd3	cep89	ENSEEEP00000007078	ENSEEEP00000037459	Uncharacterized protein.	Centrosomal protein 89.	0.574
C2cd3	lrrc45	ENSEEEP00000007078	ENSEEEP00000007186	Uncharacterized protein.	Uncharacterized protein.	0.467
C2cd3	ofd1	ENSEEEP00000007078	ENSEEEP00000026854	Uncharacterized protein.	Oral-facial-digital syndrome 1.	0.613
Cep170b	ENSEEEP00000011804	ENSEEEP00000045475	ENSEEEP00000011804	FHA domain-containing protein.	Centrosomal protein 170Ab.	0.830
Cep170b	ENSEEEP00000015339	ENSEEEP00000045475	ENSEEEP00000015339	FHA domain-containing protein.	CEP170_C domain-containing protein.	0.899
Cep170b	ENSEEEP00000027249	ENSEEEP00000045475	ENSEEEP00000027249	FHA domain-containing protein.	Coiled-coil domain containing 120.	0.415
Cep170b	LOC113568164	ENSEEEP00000045475	ENSEEEP00000000418	FHA domain-containing protein.	CDK5 regulatory subunit associated protein 2.	0.417
Cep350	LOC113580541	ENSEEEP00000025331	ENSEEEP00000014434	CAP-Gly domain-containing protein.	Uncharacterized protein.	0.559
Cep350	Sclt1	ENSEEEP00000025331	ENSEEEP00000043905	CAP-Gly domain-containing protein.	Uncharacterized protein.	0.467
Cep350	cep120	ENSEEEP00000025331	ENSEEEP00000016624	CAP-Gly domain-containing protein.	Uncharacterized protein.	0.457
Cep350	cep19	ENSEEEP00000025331	ENSEEEP00000051826	CAP-Gly domain-containing protein.	Centrosomal protein 19.	0.702
Cep350	cep89	ENSEEEP00000025331	ENSEEEP00000037459	CAP-Gly domain-containing protein.	Centrosomal protein 89.	0.602
Cep350	fgfr1op	ENSEEEP00000025331	ENSEEEP00000019886	CAP-Gly domain-containing protein.	Uncharacterized protein.	0.895
Cep350	plk4	ENSEEEP00000025331	ENSEEEP00000012632	CAP-Gly domain-containing protein.	Uncharacterized protein.	0.509
Cep350	tubd1	ENSEEEP00000025331	ENSEEEP00000006317	CAP-Gly domain-containing protein.	Tubulin domain-containing protein; Belongs to the tubulin family.	0.403