(33 nodes) Mixed, incl. Dynamin, N-terminal, and Regulation of mitochondrial fission network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113578149	Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (644 aa)
	LOC113575323	SAM domain-containing protein. (1515 aa)
	mfn2	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
	mul1	RING-type domain-containing protein. (352 aa)
	pink1	Protein kinase domain-containing protein. (579 aa)
	LOC113579803	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (159 aa)
	tbc1d17	Rab-GAP TBC domain-containing protein. (641 aa)
	LOC113569234	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (467 aa)
	LOC113578499	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (756 aa)
	mff	Uncharacterized protein. (238 aa)
	marchf5	RING-CH-type domain-containing protein. (283 aa)
	opa1	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1027 aa)
	LOC113568453	RING-type domain-containing protein. (341 aa)
	plek	Pleckstrin. (353 aa)
	LOC113581259	YME1-like 1a. (783 aa)
	tbc1d15	Rab-GAP TBC domain-containing protein. (676 aa)
	LOC113572358	Uncharacterized protein. (211 aa)
	LOC113591667	Uncharacterized protein. (294 aa)
	LOC113591661	Miff domain-containing protein. (286 aa)
	ENSEEEP00000024498	DYNc domain-containing protein. (395 aa)
	LOC113576789	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (631 aa)
	oma1	OMA1 zinc metallopeptidase. (454 aa)
	fkbp8	Peptidylprolyl isomerase. (401 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (451 aa)
	fis1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
	LOC113580906	Mab-21 domain-containing protein. (476 aa)
	fundc2	Uncharacterized protein. (147 aa)
	usp30	Ubiquitin carboxyl-terminal hydrolase. (491 aa)
	tmem115	Uncharacterized protein. (360 aa)
	LOC113589265	RING-CH-type domain-containing protein. (286 aa)
	LOC113573624	BCL2 like 13. (496 aa)
	PARL	Rhomboid domain-containing protein. (360 aa)
	dnm1l	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (713 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000024498	LOC113578499	ENSEEEP00000024498	ENSEEEP00000007383	DYNc domain-containing protein.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.416
ENSEEEP00000024498	LOC113580906	ENSEEEP00000024498	ENSEEEP00000039131	DYNc domain-containing protein.	Mab-21 domain-containing protein.	0.435
ENSEEEP00000024498	LOC113591667	ENSEEEP00000024498	ENSEEEP00000022652	DYNc domain-containing protein.	Uncharacterized protein.	0.400
ENSEEEP00000024498	mfn2	ENSEEEP00000024498	ENSEEEP00000002425	DYNc domain-containing protein.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.416
ENSEEEP00000024498	oma1	ENSEEEP00000024498	ENSEEEP00000024741	DYNc domain-containing protein.	OMA1 zinc metallopeptidase.	0.459
ENSEEEP00000024498	pink1	ENSEEEP00000024498	ENSEEEP00000003966	DYNc domain-containing protein.	Protein kinase domain-containing protein.	0.639
ENSEEEP00000024498	prkn	ENSEEEP00000024498	ENSEEEP00000026210	DYNc domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.660
LOC113568453	fkbp8	ENSEEEP00000014552	ENSEEEP00000025523	RING-type domain-containing protein.	Peptidylprolyl isomerase.	0.541
LOC113568453	prkn	ENSEEEP00000014552	ENSEEEP00000026210	RING-type domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.436
LOC113568453	tmem115	ENSEEEP00000014552	ENSEEEP00000044144	RING-type domain-containing protein.	Uncharacterized protein.	0.573
LOC113568453	usp30	ENSEEEP00000014552	ENSEEEP00000043587	RING-type domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase.	0.741
LOC113569234	LOC113578499	ENSEEEP00000006147	ENSEEEP00000007383	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.416
LOC113569234	LOC113580906	ENSEEEP00000006147	ENSEEEP00000039131	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Mab-21 domain-containing protein.	0.435
LOC113569234	LOC113591667	ENSEEEP00000006147	ENSEEEP00000022652	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.400
LOC113569234	mfn2	ENSEEEP00000006147	ENSEEEP00000002425	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.416
LOC113569234	oma1	ENSEEEP00000006147	ENSEEEP00000024741	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	OMA1 zinc metallopeptidase.	0.459
LOC113569234	pink1	ENSEEEP00000006147	ENSEEEP00000003966	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Protein kinase domain-containing protein.	0.639
LOC113569234	prkn	ENSEEEP00000006147	ENSEEEP00000026210	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.660
LOC113572358	tbc1d15	ENSEEEP00000022493	ENSEEEP00000020661	Uncharacterized protein.	Rab-GAP TBC domain-containing protein.	0.952
LOC113572358	tbc1d17	ENSEEEP00000022493	ENSEEEP00000004147	Uncharacterized protein.	Rab-GAP TBC domain-containing protein.	0.952