(40 nodes) Mixed, incl. Calnexin/calreticulin cycle, and Protein folding in endoplasmic reticulum network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ero1b	Uncharacterized protein. (479 aa)
	LOC113579808	Uncharacterized protein. (509 aa)
	ankrd45	ANK_REP_REGION domain-containing protein. (217 aa)
	prkcsh	Protein kinase C substrate 80K-H. (530 aa)
	LOC113573425	Uncharacterized protein. (222 aa)
	p4hb	Protein disulfide-isomerase. (539 aa)
	edem1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (631 aa)
	dnajc10	Uncharacterized protein. (803 aa)
	PDIA6	Uncharacterized protein; Belongs to the protein disulfide isomerase family. (447 aa)
	sdf2l1	Uncharacterized protein. (217 aa)
	LOC113570520	Uncharacterized protein; Belongs to the protein disulfide isomerase family. (446 aa)
	manf	Uncharacterized protein. (180 aa)
	mydgf	Uncharacterized protein. (172 aa)
	sil1	Fes1 domain-containing protein. (486 aa)
	LOC113588271	Glyco_transf_24 domain-containing protein. (112 aa)
	LOC113574940	Protein disulfide-isomerase. (547 aa)
	LOC113582418	Uncharacterized protein. (1524 aa)
	dnajc3	Uncharacterized protein. (507 aa)
	LOC113574953	Thioredoxin domain-containing protein. (508 aa)
	ero1a	Uncharacterized protein. (463 aa)
	LOC113575017	Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (690 aa)
	hyou1	Uncharacterized protein. (1012 aa)
	LOC113588334	Uncharacterized protein. (624 aa)
	LOC113573433	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (786 aa)
	txndc11	Thioredoxin domain containing 11. (755 aa)
	hspa5	Uncharacterized protein; Belongs to the heat shock protein 70 family. (665 aa)
	pdia4	Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. (639 aa)
	LOC113591874	Zgc:171967; Belongs to the glycosyl hydrolase 31 family. (927 aa)
	LOC113585882	PRKCSH-like domain-containing protein. (247 aa)
	LOC113590320	UDP-glucose glycoprotein glucosyltransferase 1. (944 aa)
	dnajb11	J domain-containing protein. (360 aa)
	hsp90b1	HATPase_c domain-containing protein. (811 aa)
	creld2	Uncharacterized protein. (363 aa)
	LOC113574193	Si:ch211-274f20.2. (481 aa)
	LOC113585317	Glucosidase, alpha; neutral AB; Belongs to the glycosyl hydrolase 31 family. (959 aa)
	LOC113585342	CRIB domain-containing protein. (76 aa)
	Secisbp2l	Uncharacterized protein. (556 aa)
	LOC113576976	Uncharacterized protein. (1709 aa)
	canx	Uncharacterized protein. (608 aa)
	LOC113583115	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (572 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC113570520	LOC113574193	ENSEEEP00000019167	ENSEEEP00000047925	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Si:ch211-274f20.2.	0.532
LOC113570520	LOC113574940	ENSEEEP00000019167	ENSEEEP00000025134	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Protein disulfide-isomerase.	0.624
LOC113570520	LOC113574953	ENSEEEP00000019167	ENSEEEP00000026211	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Thioredoxin domain-containing protein.	0.589
LOC113570520	LOC113579808	ENSEEEP00000019167	ENSEEEP00000004090	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein.	0.712
LOC113570520	LOC113583115	ENSEEEP00000019167	ENSEEEP00000052363	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.419
LOC113570520	LOC113588334	ENSEEEP00000019167	ENSEEEP00000031573	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein.	0.540
LOC113570520	ankrd45	ENSEEEP00000019167	ENSEEEP00000009399	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	ANK_REP_REGION domain-containing protein.	0.555
LOC113570520	canx	ENSEEEP00000019167	ENSEEEP00000050713	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein.	0.540
LOC113570520	creld2	ENSEEEP00000019167	ENSEEEP00000045565	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein.	0.513
LOC113570520	dnajb11	ENSEEEP00000019167	ENSEEEP00000040718	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	J domain-containing protein.	0.820
LOC113570520	dnajc3	ENSEEEP00000019167	ENSEEEP00000026014	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein.	0.712
LOC113570520	edem1	ENSEEEP00000019167	ENSEEEP00000012367	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.419
LOC113570520	ero1a	ENSEEEP00000019167	ENSEEEP00000026436	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein.	0.646
LOC113570520	ero1b	ENSEEEP00000019167	ENSEEEP00000001913	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein.	0.963
LOC113570520	hsp90b1	ENSEEEP00000019167	ENSEEEP00000041052	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	HATPase_c domain-containing protein.	0.934
LOC113570520	hspa5	ENSEEEP00000019167	ENSEEEP00000034832	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.898
LOC113570520	hyou1	ENSEEEP00000019167	ENSEEEP00000031412	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein.	0.691
LOC113570520	manf	ENSEEEP00000019167	ENSEEEP00000020935	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Uncharacterized protein.	0.492
LOC113570520	p4hb	ENSEEEP00000019167	ENSEEEP00000012003	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Protein disulfide-isomerase.	0.619
LOC113570520	pdia4	ENSEEEP00000019167	ENSEEEP00000035214	Uncharacterized protein; Belongs to the protein disulfide isomerase family.	Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.	0.634