(25 nodes) Mixed, incl. Membrane attack complex component/perforin/complement C9, and Scavenging by Class H Receptors network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	c8b	MACPF domain-containing protein. (587 aa)
	C8A	MACPF domain-containing protein. (595 aa)
	ENSEEEP00000002078	Si:ch211-188c16.1. (477 aa)
	ENSEEEP00000002721	Uncharacterized protein. (284 aa)
	ENSEEEP00000005158	Uncharacterized protein. (535 aa)
	ENSEEEP00000005933	Uncharacterized protein. (343 aa)
	ENSEEEP00000007399	Uncharacterized protein. (134 aa)
	ENSEEEP00000012997	Uncharacterized protein. (154 aa)
	c7	Complement component 7b. (823 aa)
	c6	Complement component 6. (932 aa)
	stab1	Stabilin 1. (2506 aa)
	ENSEEEP00000016679	Uncharacterized protein. (176 aa)
	ENSEEEP00000016707	Uncharacterized protein. (498 aa)
	scarf1	Scavenger receptor class F, member 1. (814 aa)
	LOC113590596	Uncharacterized protein. (190 aa)
	ENSEEEP00000022863	Uncharacterized protein. (181 aa)
	gucd1	Uncharacterized protein. (226 aa)
	LOC113574840	Uncharacterized protein. (376 aa)
	c8g	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (219 aa)
	clu	Clusterin; Belongs to the clusterin family. (442 aa)
	LOC113586351	SPARC-like 1. (534 aa)
	LOC113587510	Complement component 7a. (804 aa)
	c9	Complement component 9. (633 aa)
	ENSEEEP00000039438	Secreted phosphoprotein 1. (278 aa)
	LOC113591431	Dickkopf_N domain-containing protein. (215 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C8A	LOC113587510	ENSEEEP00000002049	ENSEEEP00000037962	MACPF domain-containing protein.	Complement component 7a.	0.604
C8A	c6	ENSEEEP00000002049	ENSEEEP00000014883	MACPF domain-containing protein.	Complement component 6.	0.617
C8A	c7	ENSEEEP00000002049	ENSEEEP00000013883	MACPF domain-containing protein.	Complement component 7b.	0.540
C8A	c8b	ENSEEEP00000002049	ENSEEEP00000002028	MACPF domain-containing protein.	MACPF domain-containing protein.	0.782
C8A	c8g	ENSEEEP00000002049	ENSEEEP00000035160	MACPF domain-containing protein.	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.	0.983
C8A	c9	ENSEEEP00000002049	ENSEEEP00000039234	MACPF domain-containing protein.	Complement component 9.	0.972
ENSEEEP00000002078	ENSEEEP00000002721	ENSEEEP00000002078	ENSEEEP00000002721	Si:ch211-188c16.1.	Uncharacterized protein.	0.462
ENSEEEP00000002078	ENSEEEP00000007399	ENSEEEP00000002078	ENSEEEP00000007399	Si:ch211-188c16.1.	Uncharacterized protein.	0.451
ENSEEEP00000002078	ENSEEEP00000012997	ENSEEEP00000002078	ENSEEEP00000012997	Si:ch211-188c16.1.	Uncharacterized protein.	0.451
ENSEEEP00000002078	LOC113574840	ENSEEEP00000002078	ENSEEEP00000023921	Si:ch211-188c16.1.	Uncharacterized protein.	0.551
ENSEEEP00000002078	c8g	ENSEEEP00000002078	ENSEEEP00000035160	Si:ch211-188c16.1.	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.	0.451
ENSEEEP00000002078	clu	ENSEEEP00000002078	ENSEEEP00000036752	Si:ch211-188c16.1.	Clusterin; Belongs to the clusterin family.	0.413
ENSEEEP00000002721	ENSEEEP00000002078	ENSEEEP00000002721	ENSEEEP00000002078	Uncharacterized protein.	Si:ch211-188c16.1.	0.462
ENSEEEP00000002721	c8b	ENSEEEP00000002721	ENSEEEP00000002028	Uncharacterized protein.	MACPF domain-containing protein.	0.529
ENSEEEP00000002721	clu	ENSEEEP00000002721	ENSEEEP00000036752	Uncharacterized protein.	Clusterin; Belongs to the clusterin family.	0.448
ENSEEEP00000005158	LOC113586351	ENSEEEP00000005158	ENSEEEP00000037253	Uncharacterized protein.	SPARC-like 1.	0.521
ENSEEEP00000005933	LOC113586351	ENSEEEP00000005933	ENSEEEP00000037253	Uncharacterized protein.	SPARC-like 1.	0.521
ENSEEEP00000007399	ENSEEEP00000002078	ENSEEEP00000007399	ENSEEEP00000002078	Uncharacterized protein.	Si:ch211-188c16.1.	0.451
ENSEEEP00000007399	c8b	ENSEEEP00000007399	ENSEEEP00000002028	Uncharacterized protein.	MACPF domain-containing protein.	0.527
ENSEEEP00000007399	clu	ENSEEEP00000007399	ENSEEEP00000036752	Uncharacterized protein.	Clusterin; Belongs to the clusterin family.	0.410