(32 nodes) cGMP metabolic process, and GAF domain network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113578209	Uncharacterized protein. (128 aa)
	LOC113578210	Uncharacterized protein. (152 aa)
	ENSEEEP00000004618	Uncharacterized protein. (103 aa)
	pde5a	Phosphodiesterase. (865 aa)
	PDE2A	Phosphodiesterase. (751 aa)
	LOC113589373	Uncharacterized protein. (87 aa)
	ENSEEEP00000009640	Gla domain-containing protein. (106 aa)
	LOC113581011	Phosphodiesterase. (538 aa)
	LOC113583412	Guanylate cyclase. (1065 aa)
	npr2	Guanylate cyclase. (1043 aa)
	LOC113576564	Guanylate cyclase. (1105 aa)
	pde11a	Phosphodiesterase. (897 aa)
	LOC113574817	Guanylate cyclase. (1073 aa)
	pde9a	Phosphodiesterase. (528 aa)
	ENSEEEP00000024135	Si:dkey-219c10.4; Belongs to the cyclic nucleotide phosphodiesterase family. (457 aa)
	LOC113585750	Natriuretic peptide C. (131 aa)
	adcy5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1185 aa)
	trim32	Uncharacterized protein. (674 aa)
	LOC113579603	Phosphodiesterase. (498 aa)
	LOC113571233	Guanylate cyclase. (1086 aa)
	LOC113586319	Guanylate cyclase. (1089 aa)
	ENSEEEP00000036318	Uncharacterized protein. (146 aa)
	LOC113567615	Uncharacterized protein. (203 aa)
	pde6c	Phosphodiesterase. (849 aa)
	ENSEEEP00000039768	Guanylate cyclase. (716 aa)
	ENSEEEP00000040429	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (143 aa)
	ENSEEEP00000040430	Protein kinase domain-containing protein. (256 aa)
	enpp1	Ectonucleotide pyrophosphatase/phosphodiesterase 1. (835 aa)
	LOC113581896	Phosphodiesterase. (733 aa)
	npr3	ANF_receptor domain-containing protein. (498 aa)
	guca1a	Uncharacterized protein. (189 aa)
	LOC113584860	Guanylate cyclase. (1064 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000004618	ENSEEEP00000039768	ENSEEEP00000004618	ENSEEEP00000039768	Uncharacterized protein.	Guanylate cyclase.	0.802
ENSEEEP00000004618	ENSEEEP00000040429	ENSEEEP00000004618	ENSEEEP00000040429	Uncharacterized protein.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.802
ENSEEEP00000004618	ENSEEEP00000040430	ENSEEEP00000004618	ENSEEEP00000040430	Uncharacterized protein.	Protein kinase domain-containing protein.	0.802
ENSEEEP00000004618	LOC113571233	ENSEEEP00000004618	ENSEEEP00000034843	Uncharacterized protein.	Guanylate cyclase.	0.979
ENSEEEP00000004618	LOC113574817	ENSEEEP00000004618	ENSEEEP00000023172	Uncharacterized protein.	Guanylate cyclase.	0.797
ENSEEEP00000004618	LOC113576564	ENSEEEP00000004618	ENSEEEP00000021524	Uncharacterized protein.	Guanylate cyclase.	0.760
ENSEEEP00000004618	LOC113578210	ENSEEEP00000004618	ENSEEEP00000004611	Uncharacterized protein.	Uncharacterized protein.	0.868
ENSEEEP00000004618	LOC113583412	ENSEEEP00000004618	ENSEEEP00000018822	Uncharacterized protein.	Guanylate cyclase.	0.979
ENSEEEP00000004618	LOC113584860	ENSEEEP00000004618	ENSEEEP00000052303	Uncharacterized protein.	Guanylate cyclase.	0.797
ENSEEEP00000004618	LOC113585750	ENSEEEP00000004618	ENSEEEP00000026464	Uncharacterized protein.	Natriuretic peptide C.	0.668
ENSEEEP00000004618	LOC113586319	ENSEEEP00000004618	ENSEEEP00000035109	Uncharacterized protein.	Guanylate cyclase.	0.760
ENSEEEP00000004618	adcy5	ENSEEEP00000004618	ENSEEEP00000031727	Uncharacterized protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.508
ENSEEEP00000004618	npr2	ENSEEEP00000004618	ENSEEEP00000020759	Uncharacterized protein.	Guanylate cyclase.	0.802
ENSEEEP00000004618	npr3	ENSEEEP00000004618	ENSEEEP00000048536	Uncharacterized protein.	ANF_receptor domain-containing protein.	0.972
ENSEEEP00000009640	LOC113589373	ENSEEEP00000009640	ENSEEEP00000009636	Gla domain-containing protein.	Uncharacterized protein.	0.581
ENSEEEP00000024135	trim32	ENSEEEP00000024135	ENSEEEP00000033279	Si:dkey-219c10.4; Belongs to the cyclic nucleotide phosphodiesterase family.	Uncharacterized protein.	0.412
ENSEEEP00000036318	LOC113571233	ENSEEEP00000036318	ENSEEEP00000034843	Uncharacterized protein.	Guanylate cyclase.	0.905
ENSEEEP00000036318	LOC113574817	ENSEEEP00000036318	ENSEEEP00000023172	Uncharacterized protein.	Guanylate cyclase.	0.915
ENSEEEP00000036318	LOC113576564	ENSEEEP00000036318	ENSEEEP00000021524	Uncharacterized protein.	Guanylate cyclase.	0.905
ENSEEEP00000036318	LOC113579603	ENSEEEP00000036318	ENSEEEP00000033911	Uncharacterized protein.	Phosphodiesterase.	0.675