STRINGSTRING
ENSEEEP00000005542 ENSEEEP00000005542 abcb6 abcb6 mms19 mms19 ciao3 ciao3 nubp2 nubp2 glrx3 glrx3 fdx2 fdx2 lyrm4 lyrm4 MOCOS MOCOS LOC113567855 LOC113567855 abcb7 abcb7 isca2 isca2 nfs1 nfs1 FADS6 FADS6 ciao1 ciao1 fxn fxn fdx1 fdx1 LOC113585789 LOC113585789 Bola1 Bola1 narf narf ndor1 ndor1 ciapin1 ciapin1 nubpl nubpl LOC113577340 LOC113577340 ciao2b ciao2b ciao2a ciao2a nubp1 nubp1 fdxr fdxr iscu iscu isca1 isca1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSEEEP000000055422Fe-2S ferredoxin-type domain-containing protein. (196 aa)
abcb6ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (846 aa)
mms19Uncharacterized protein. (1028 aa)
ciao3Nuclear prelamin A recognition factor-like; Belongs to the NARF family. (479 aa)
nubp2Cytosolic Fe-S cluster assembly factor nubp2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (268 aa)
glrx3Uncharacterized protein. (335 aa)
fdx22Fe-2S ferredoxin-type domain-containing protein. (197 aa)
lyrm4Uncharacterized protein; Belongs to the complex I LYR family. (91 aa)
MOCOSMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (845 aa)
LOC113567855Nfu_N domain-containing protein. (252 aa)
abcb7ATP-binding cassette, sub-family B (MDR/TAP), member 7. (701 aa)
isca2Fe-S_biosyn domain-containing protein. (173 aa)
nfs1Aminotran_5 domain-containing protein. (451 aa)
FADS6FA_desaturase domain-containing protein. (349 aa)
ciao1Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Belongs to the WD repeat CIA1 family. (333 aa)
fxnUncharacterized protein. (254 aa)
fdx12Fe-2S ferredoxin-type domain-containing protein. (181 aa)
LOC113585789Nfu_N domain-containing protein. (262 aa)
Bola1BolA family member 1; Belongs to the BolA/IbaG family. (99 aa)
narfFe_hyd_SSU domain-containing protein; Belongs to the NARF family. (465 aa)
ndor1NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (649 aa)
ciapin1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (335 aa)
nubplUncharacterized protein. (326 aa)
LOC113577340Uncharacterized protein; Belongs to the BolA/IbaG family. (86 aa)
ciao2bCytosolic iron-sulfur assembly component 2B. (169 aa)
ciao2aFeS_assembly_P domain-containing protein. (157 aa)
nubp1Cytosolic Fe-S cluster assembly factor nubp1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (345 aa)
fdxrNADPH:adrenodoxin oxidoreductase, mitochondrial. (441 aa)
iscuIron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (184 aa)
isca1Fe-S_biosyn domain-containing protein. (129 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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