6 items (Electrophorus electricus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nbn	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (816 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1181 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
	ENSEEEP00000032310	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa)
	rbbp8	SAE2 domain-containing protein. (131 aa)
	LOC113576847	RING-type domain-containing protein. (995 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000032310	LOC113576847	ENSEEEP00000032310	ENSEEEP00000047536	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RING-type domain-containing protein.	0.960
ENSEEEP00000032310	mre11	ENSEEEP00000032310	ENSEEEP00000024860	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.962
ENSEEEP00000032310	nbn	ENSEEEP00000032310	ENSEEEP00000010371	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.999
ENSEEEP00000032310	rad50	ENSEEEP00000032310	ENSEEEP00000013894	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RAD50 homolog, double strand break repair protein.	0.991
ENSEEEP00000032310	rbbp8	ENSEEEP00000032310	ENSEEEP00000034871	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	SAE2 domain-containing protein.	0.909
LOC113576847	ENSEEEP00000032310	ENSEEEP00000047536	ENSEEEP00000032310	RING-type domain-containing protein.	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.960
LOC113576847	mre11	ENSEEEP00000047536	ENSEEEP00000024860	RING-type domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.957
LOC113576847	nbn	ENSEEEP00000047536	ENSEEEP00000010371	RING-type domain-containing protein.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.941
LOC113576847	rad50	ENSEEEP00000047536	ENSEEEP00000013894	RING-type domain-containing protein.	RAD50 homolog, double strand break repair protein.	0.821
LOC113576847	rbbp8	ENSEEEP00000047536	ENSEEEP00000034871	RING-type domain-containing protein.	SAE2 domain-containing protein.	0.997
mre11	ENSEEEP00000032310	ENSEEEP00000024860	ENSEEEP00000032310	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.962
mre11	LOC113576847	ENSEEEP00000024860	ENSEEEP00000047536	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	RING-type domain-containing protein.	0.957
mre11	nbn	ENSEEEP00000024860	ENSEEEP00000010371	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.981
mre11	rad50	ENSEEEP00000024860	ENSEEEP00000013894	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	RAD50 homolog, double strand break repair protein.	0.969
mre11	rbbp8	ENSEEEP00000024860	ENSEEEP00000034871	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	SAE2 domain-containing protein.	0.909
nbn	ENSEEEP00000032310	ENSEEEP00000010371	ENSEEEP00000032310	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.999
nbn	LOC113576847	ENSEEEP00000010371	ENSEEEP00000047536	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	RING-type domain-containing protein.	0.941
nbn	mre11	ENSEEEP00000010371	ENSEEEP00000024860	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.981
nbn	rad50	ENSEEEP00000010371	ENSEEEP00000013894	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	RAD50 homolog, double strand break repair protein.	0.993
nbn	rbbp8	ENSEEEP00000010371	ENSEEEP00000034871	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	SAE2 domain-containing protein.	0.981