Your Input: | |||||
rif1 | Replication timing regulatory factor 1. (2379 aa) | ||||
LOC113569058 | AAA_23 domain-containing protein. (469 aa) | ||||
ENSEEEP00000006834 | Uncharacterized protein. (110 aa) | ||||
ENSEEEP00000007003 | AAA_23 domain-containing protein. (53 aa) | ||||
dclre1c | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (683 aa) | ||||
rad51d | RECA_2 domain-containing protein. (338 aa) | ||||
ENSEEEP00000000428 | Uncharacterized protein. (383 aa) | ||||
rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (624 aa) | ||||
prkdc | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4099 aa) | ||||
parp3 | Poly [ADP-ribose] polymerase. (527 aa) | ||||
ENSEEEP00000051173 | TCF3 (E2A) fusion partner. (165 aa) | ||||
ENSEEEP00000050839 | Metallophos domain-containing protein. (106 aa) | ||||
stn1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (369 aa) | ||||
mcrs1 | FHA domain-containing protein. (475 aa) | ||||
ccne2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (394 aa) | ||||
CCNE2 | Cyclin E2; Belongs to the cyclin family. (320 aa) | ||||
xrcc5 | Ku domain-containing protein. (740 aa) | ||||
ENSEEEP00000043857 | Telomeric repeat binding factor a. (471 aa) | ||||
LOC113591471 | Prostaglandin E synthase 3b (cytosolic). (159 aa) | ||||
hus1 | Checkpoint protein; Belongs to the HUS1 family. (283 aa) | ||||
fbxo4 | F-box protein 4. (371 aa) | ||||
dkc1 | PUA domain-containing protein. (525 aa) | ||||
zbtb48 | Zinc finger and BTB domain containing 48. (596 aa) | ||||
ercc1 | Uncharacterized protein. (346 aa) | ||||
LOC113577337 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (263 aa) | ||||
lto1 | Yae1_N domain-containing protein. (141 aa) | ||||
LOC113567594 | Si:dkey-119f1.1. (1009 aa) | ||||
ENSEEEP00000035972 | Zinc finger protein 827. (680 aa) | ||||
LOC113567536 | Uncharacterized protein. (1086 aa) | ||||
tert | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1062 aa) | ||||
blm | BLM RecQ like helicase. (1281 aa) | ||||
ENSEEEP00000034928 | Uncharacterized protein. (435 aa) | ||||
nsmce2 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (257 aa) | ||||
atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2627 aa) | ||||
wrap53 | WD repeat containing, antisense to TP53. (519 aa) | ||||
tprkb | Uncharacterized protein; Belongs to the CGI121/TPRKB family. (174 aa) | ||||
ENSEEEP00000032310 | ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa) | ||||
xrcc1 | X-ray repair complementing defective repair in Chinese hamster cells 1. (539 aa) | ||||
LOC113589524 | RECA_2 domain-containing protein. (121 aa) | ||||
ino80 | Uncharacterized protein. (1128 aa) | ||||
uchl5 | Ubiquitin carboxyl-terminal hydrolase. (345 aa) | ||||
pif1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (636 aa) | ||||
mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa) | ||||
smc5 | Structural maintenance of chromosomes 5. (1083 aa) | ||||
xrcc6 | Uncharacterized protein. (627 aa) | ||||
LOC113582318 | INO80 complex subunit Da. (652 aa) | ||||
terf2ip | Telomeric repeat binding factor 2, interacting protein. (536 aa) | ||||
ercc4 | ERCC4 domain-containing protein. (899 aa) | ||||
pinx1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (181 aa) | ||||
ENSEEEP00000019307 | Uncharacterized protein. (258 aa) | ||||
pot1 | Protection of telomeres 1 homolog. (767 aa) | ||||
ENSEEEP00000018711 | Zgc:101664. (195 aa) | ||||
LOC113582267 | Breast cancer 2, early onset. (2391 aa) | ||||
rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) | ||||
dclre1b | DNA cross-link repair 1B. (580 aa) | ||||
xrcc3 | RECA_2 domain-containing protein. (355 aa) | ||||
nhp2 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa) | ||||
gar1 | H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (202 aa) | ||||
rad50 | RAD50 homolog, double strand break repair protein. (1181 aa) | ||||
LOC113592198 | Uncharacterized protein. (632 aa) | ||||
dclre1a | DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (951 aa) | ||||
nop10 | Uncharacterized protein. (64 aa) | ||||
LOC113578292 | TINF2_N domain-containing protein. (598 aa) | ||||
recql4 | RecQ helicase-like 4. (817 aa) | ||||
telo2 | TEL2, telomere maintenance 2, homolog (S. cerevisiae). (850 aa) | ||||
nbn | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (816 aa) | ||||
nfrkb | Nuclear factor related to kappaB binding protein. (1268 aa) | ||||
ptges3 | CS domain-containing protein. (159 aa) | ||||
rtel1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1163 aa) | ||||
LOC113568250 | RAD51 paralog C. (260 aa) | ||||
ino80e | Uncharacterized protein. (386 aa) |