STRINGSTRING
rif1 rif1 LOC113569058 LOC113569058 ENSEEEP00000006834 ENSEEEP00000006834 ENSEEEP00000007003 ENSEEEP00000007003 dclre1c dclre1c rad51d rad51d ENSEEEP00000000428 ENSEEEP00000000428 rpa1 rpa1 prkdc prkdc parp3 parp3 ENSEEEP00000051173 ENSEEEP00000051173 ENSEEEP00000050839 ENSEEEP00000050839 stn1 stn1 mcrs1 mcrs1 ccne2 ccne2 CCNE2 CCNE2 xrcc5 xrcc5 ENSEEEP00000043857 ENSEEEP00000043857 LOC113591471 LOC113591471 hus1 hus1 fbxo4 fbxo4 dkc1 dkc1 zbtb48 zbtb48 ercc1 ercc1 LOC113577337 LOC113577337 lto1 lto1 LOC113567594 LOC113567594 ENSEEEP00000035972 ENSEEEP00000035972 LOC113567536 LOC113567536 tert tert blm blm ENSEEEP00000034928 ENSEEEP00000034928 nsmce2 nsmce2 atr atr wrap53 wrap53 tprkb tprkb ENSEEEP00000032310 ENSEEEP00000032310 xrcc1 xrcc1 LOC113589524 LOC113589524 ino80 ino80 uchl5 uchl5 pif1 pif1 mre11 mre11 smc5 smc5 xrcc6 xrcc6 LOC113582318 LOC113582318 terf2ip terf2ip ercc4 ercc4 pinx1 pinx1 ENSEEEP00000019307 ENSEEEP00000019307 pot1 pot1 ENSEEEP00000018711 ENSEEEP00000018711 LOC113582267 LOC113582267 rad51 rad51 dclre1b dclre1b xrcc3 xrcc3 nhp2 nhp2 gar1 gar1 rad50 rad50 LOC113592198 LOC113592198 dclre1a dclre1a nop10 nop10 LOC113578292 LOC113578292 recql4 recql4 telo2 telo2 nbn nbn nfrkb nfrkb ptges3 ptges3 rtel1 rtel1 LOC113568250 LOC113568250 ino80e ino80e
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rif1Replication timing regulatory factor 1. (2379 aa)
LOC113569058AAA_23 domain-containing protein. (469 aa)
ENSEEEP00000006834Uncharacterized protein. (110 aa)
ENSEEEP00000007003AAA_23 domain-containing protein. (53 aa)
dclre1cDNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (683 aa)
rad51dRECA_2 domain-containing protein. (338 aa)
ENSEEEP00000000428Uncharacterized protein. (383 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (624 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4099 aa)
parp3Poly [ADP-ribose] polymerase. (527 aa)
ENSEEEP00000051173TCF3 (E2A) fusion partner. (165 aa)
ENSEEEP00000050839Metallophos domain-containing protein. (106 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (369 aa)
mcrs1FHA domain-containing protein. (475 aa)
ccne2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (394 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (320 aa)
xrcc5Ku domain-containing protein. (740 aa)
ENSEEEP00000043857Telomeric repeat binding factor a. (471 aa)
LOC113591471Prostaglandin E synthase 3b (cytosolic). (159 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (283 aa)
fbxo4F-box protein 4. (371 aa)
dkc1PUA domain-containing protein. (525 aa)
zbtb48Zinc finger and BTB domain containing 48. (596 aa)
ercc1Uncharacterized protein. (346 aa)
LOC113577337Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (263 aa)
lto1Yae1_N domain-containing protein. (141 aa)
LOC113567594Si:dkey-119f1.1. (1009 aa)
ENSEEEP00000035972Zinc finger protein 827. (680 aa)
LOC113567536Uncharacterized protein. (1086 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1062 aa)
blmBLM RecQ like helicase. (1281 aa)
ENSEEEP00000034928Uncharacterized protein. (435 aa)
nsmce2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (257 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2627 aa)
wrap53WD repeat containing, antisense to TP53. (519 aa)
tprkbUncharacterized protein; Belongs to the CGI121/TPRKB family. (174 aa)
ENSEEEP00000032310ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (539 aa)
LOC113589524RECA_2 domain-containing protein. (121 aa)
ino80Uncharacterized protein. (1128 aa)
uchl5Ubiquitin carboxyl-terminal hydrolase. (345 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (636 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
smc5Structural maintenance of chromosomes 5. (1083 aa)
xrcc6Uncharacterized protein. (627 aa)
LOC113582318INO80 complex subunit Da. (652 aa)
terf2ipTelomeric repeat binding factor 2, interacting protein. (536 aa)
ercc4ERCC4 domain-containing protein. (899 aa)
pinx1PIN2 (TERF1) interacting telomerase inhibitor 1. (181 aa)
ENSEEEP00000019307Uncharacterized protein. (258 aa)
pot1Protection of telomeres 1 homolog. (767 aa)
ENSEEEP00000018711Zgc:101664. (195 aa)
LOC113582267Breast cancer 2, early onset. (2391 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
dclre1bDNA cross-link repair 1B. (580 aa)
xrcc3RECA_2 domain-containing protein. (355 aa)
nhp2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa)
gar1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (202 aa)
rad50RAD50 homolog, double strand break repair protein. (1181 aa)
LOC113592198Uncharacterized protein. (632 aa)
dclre1aDNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (951 aa)
nop10Uncharacterized protein. (64 aa)
LOC113578292TINF2_N domain-containing protein. (598 aa)
recql4RecQ helicase-like 4. (817 aa)
telo2TEL2, telomere maintenance 2, homolog (S. cerevisiae). (850 aa)
nbnNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (816 aa)
nfrkbNuclear factor related to kappaB binding protein. (1268 aa)
ptges3CS domain-containing protein. (159 aa)
rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1163 aa)
LOC113568250RAD51 paralog C. (260 aa)
ino80eUncharacterized protein. (386 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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