STRINGSTRING
rad51d rad51d nbn nbn top3a top3a mcm3 mcm3 recql4 recql4 zswim7 zswim7 mcm9 mcm9 mcm5 mcm5 xrcc3 xrcc3 ENSEEEP00000016716 ENSEEEP00000016716 rad51 rad51 Rev3l Rev3l ENSEEEP00000018543 ENSEEEP00000018543 LOC113582267 LOC113582267 LOC113578445 LOC113578445 ENSEEEP00000019307 ENSEEEP00000019307 nipbl nipbl mcm8 mcm8 mms22l mms22l MCMDC2 MCMDC2 ercc4 ercc4 cdc45 cdc45 dmc1 dmc1 swi5 swi5 spidr spidr mcm4 mcm4 cdc7 cdc7 smc5 smc5 rpa3 rpa3 mre11 mre11 gins4 gins4 fancb fancb ino80 ino80 poll poll LOC113589524 LOC113589524 recql recql xrcc1 xrcc1 psmd14 psmd14 helq helq ENSEEEP00000032310 ENSEEEP00000032310 Aunip Aunip rec8 rec8 nsmce2 nsmce2 LOC113591806 LOC113591806 rad51ap1 rad51ap1 rbbp8 rbbp8 blm blm ankle1 ankle1 gins2 gins2 Recql5 Recql5 ENSEEEP00000037634 ENSEEEP00000037634 ENSEEEP00000037636 ENSEEEP00000037636 LOC113584242 LOC113584242 fbh1 fbh1 LOC113575219 LOC113575219 LOC113577337 LOC113577337 XRCC2 XRCC2 ppp4c ppp4c mcm7 mcm7 mus81 mus81 ap5s1 ap5s1 LOC113575331 LOC113575331 LOC113569503 LOC113569503 rmi2 rmi2 LOC113585995 LOC113585995 nsmce1 nsmce1 rpa1 rpa1 ap5z1 ap5z1 samhd1 samhd1 exd2 exd2 LOC113584344 LOC113584344 LOC113575351 LOC113575351 rmi1 rmi1 LOC113568250 LOC113568250 ENSEEEP00000004636 ENSEEEP00000004636 ENSEEEP00000004640 ENSEEEP00000004640 LOC113578819 LOC113578819 ENSEEEP00000050839 ENSEEEP00000050839 LOC113573002 LOC113573002 mcm2 mcm2 LOC113588689 LOC113588689 zfyve26 zfyve26 fan1 fan1 mcm6 mcm6 LOC113576847 LOC113576847 sem1 sem1 rad52 rad52 tonsl tonsl ENSEEEP00000043756 ENSEEEP00000043756 hus1 hus1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rad51dRECA_2 domain-containing protein. (338 aa)
nbnNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (816 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1009 aa)
mcm3DNA helicase; Belongs to the MCM family. (815 aa)
recql4RecQ helicase-like 4. (817 aa)
zswim7SWIM-type domain-containing protein. (145 aa)
mcm9MCM domain-containing protein; Belongs to the MCM family. (1143 aa)
mcm5DNA helicase; Belongs to the MCM family. (738 aa)
xrcc3RECA_2 domain-containing protein. (355 aa)
ENSEEEP00000016716Helicase ATP-binding domain-containing protein. (320 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
Rev3lDNA_pol_B domain-containing protein. (304 aa)
ENSEEEP00000018543Methionine sulfoxide reductase B1b. (259 aa)
LOC113582267Breast cancer 2, early onset. (2391 aa)
LOC113578445RAD21 cohesin complex component b. (620 aa)
ENSEEEP00000019307Uncharacterized protein. (258 aa)
nipblNipped-B protein. (2652 aa)
mcm8MCM domain-containing protein; Belongs to the MCM family. (844 aa)
mms22lUncharacterized protein. (1240 aa)
MCMDC2Minichromosome maintenance domain containing 2. (372 aa)
ercc4ERCC4 domain-containing protein. (899 aa)
cdc45Uncharacterized protein. (574 aa)
dmc1DNA meiotic recombinase 1. (324 aa)
swi5SWI5 homologous recombination repair protein. (140 aa)
spidrDUF4503 domain-containing protein. (573 aa)
mcm4DNA helicase; Belongs to the MCM family. (848 aa)
cdc7Protein kinase domain-containing protein. (555 aa)
smc5Structural maintenance of chromosomes 5. (1083 aa)
rpa3Uncharacterized protein. (122 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa)
fancbUncharacterized protein. (822 aa)
ino80Uncharacterized protein. (1128 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (585 aa)
LOC113589524RECA_2 domain-containing protein. (121 aa)
recqlATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (826 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (539 aa)
psmd14MPN domain-containing protein. (330 aa)
helqUncharacterized protein. (1026 aa)
ENSEEEP00000032310ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa)
AunipUncharacterized protein. (237 aa)
rec8REC8 meiotic recombination protein b. (439 aa)
nsmce2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (257 aa)
LOC113591806Nipped-B protein. (2259 aa)
rad51ap1RAD51_interact domain-containing protein. (230 aa)
rbbp8SAE2 domain-containing protein. (131 aa)
blmBLM RecQ like helicase. (1281 aa)
ankle1Zgc:85936. (862 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (182 aa)
Recql5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (970 aa)
ENSEEEP00000037634ERCC4 domain-containing protein. (1166 aa)
ENSEEEP00000037636Helicase C-terminal domain-containing protein. (432 aa)
LOC113584242WD_REPEATS_REGION domain-containing protein. (719 aa)
fbh1F-box domain-containing protein. (1043 aa)
LOC113575219Uncharacterized protein. (287 aa)
LOC113577337Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (263 aa)
XRCC2RECA_2 domain-containing protein. (302 aa)
ppp4cSerine/threonine-protein phosphatase. (307 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (732 aa)
mus81MUS81 structure-specific endonuclease subunit. (615 aa)
ap5s1Uncharacterized protein. (200 aa)
LOC113575331Nucleic acid binding protein 1b. (203 aa)
LOC113569503Uncharacterized protein. (225 aa)
rmi2Uncharacterized protein. (147 aa)
LOC113585995DNA helicase; Belongs to the MCM family. (801 aa)
nsmce1zf-RING-like domain-containing protein. (274 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (624 aa)
ap5z1Adaptor related protein complex 5 subunit zeta 1. (668 aa)
samhd1Uncharacterized protein. (623 aa)
exd2Exonuclease 3'-5' domain containing 2. (616 aa)
LOC113584344DNA helicase; Belongs to the MCM family. (820 aa)
LOC113575351Uncharacterized protein. (215 aa)
rmi1DUF1767 domain-containing protein. (587 aa)
LOC113568250RAD51 paralog C. (260 aa)
ENSEEEP00000004636Rad21_Rec8 domain-containing protein. (66 aa)
ENSEEEP00000004640Rad21_Rec8_N domain-containing protein. (138 aa)
LOC113578819Uncharacterized protein. (638 aa)
ENSEEEP00000050839Metallophos domain-containing protein. (106 aa)
LOC113573002WD_REPEATS_REGION domain-containing protein. (682 aa)
mcm2DNA helicase; Belongs to the MCM family. (908 aa)
LOC113588689Nucleic acid binding protein 2. (156 aa)
zfyve26Zinc finger, FYVE domain containing 26. (2547 aa)
fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1005 aa)
mcm6DNA helicase; Belongs to the MCM family. (830 aa)
LOC113576847RING-type domain-containing protein. (995 aa)
sem1Uncharacterized protein. (70 aa)
rad52RAD52 homolog, DNA repair protein. (287 aa)
tonslTonsoku-like, DNA repair protein. (1431 aa)
ENSEEEP00000043756XPGI domain-containing protein. (341 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (283 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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