STRINGSTRING
rpp14 rpp14 EXOG EXOG LOC113578373 LOC113578373 Ang Ang pop5 pop5 zc3h12b zc3h12b LOC113569971 LOC113569971 dis3 dis3 ENDOV ENDOV DNA2 DNA2 LOC113589972 LOC113589972 dclre1c dclre1c mrpl44 mrpl44 tatdn1 tatdn1 ENSEEEP00000007004 ENSEEEP00000007004 rpp38 rpp38 rnaseh2a rnaseh2a LOC113568250 LOC113568250 apex1 apex1 ern1 ern1 ENSEEEP00000001936 ENSEEEP00000001936 dffb dffb LOC113569619 LOC113569619 ENSEEEP00000001158 ENSEEEP00000001158 LOC113568197 LOC113568197 piwil1 piwil1 zranb3 zranb3 dbr1 dbr1 rcl1 rcl1 elac2 elac2 LOC113580343 LOC113580343 LOC113571916 LOC113571916 mus81 mus81 rexo4 rexo4 dnase1 dnase1 ENSEEEP00000043756 ENSEEEP00000043756 endog endog Piwil2 Piwil2 ago2 ago2 tsen54 tsen54 pelo pelo dnase2b dnase2b tsen34 tsen34 fan1 fan1 apex2 apex2 drosha drosha ENSEEEP00000050384 ENSEEEP00000050384 ENSEEEP00000050839 ENSEEEP00000050839 zc3h12a zc3h12a eme1 eme1 LOC113569782 LOC113569782 LOC113577337 LOC113577337 ENSEEEP00000039119 ENSEEEP00000039119 LOC113567770 LOC113567770 rag1 rag1 LOC113583536 LOC113583536 LOC113583535 LOC113583535 LOC113572557 LOC113572557 smg6 smg6 ankle1 ankle1 ENSEEEP00000035317 ENSEEEP00000035317 ENSEEEP00000035283 ENSEEEP00000035283 LOC113574523 LOC113574523 rbbp8 rbbp8 LOC113580907 LOC113580907 nob1 nob1 rnasek rnasek LOC113581116 LOC113581116 LOC113576618 LOC113576618 LOC113590030 LOC113590030 bivm bivm dicer1 dicer1 LOC113586234 LOC113586234 fen1 fen1 rida rida pop1 pop1 rpp30 rpp30 tsen2 tsen2 ENSEEEP00000029089 ENSEEEP00000029089 LOC113589524 LOC113589524 DNASE1L3 DNASE1L3 prorp prorp ybey ybey ENSEEEP00000027215 ENSEEEP00000027215 Ercc5 Ercc5 LACTB2 LACTB2 snd1 snd1 tsn tsn mre11 mre11 mblac1 mblac1 LOC113580795 LOC113580795 LOC113568050 LOC113568050 endou endou ercc4 ercc4 cpsf3 cpsf3 LOC113584053 LOC113584053 LOC113578936 LOC113578936 rnaseh1 rnaseh1 exo1 exo1 ENSEEEP00000019655 ENSEEEP00000019655 rnaset2 rnaset2 nudt12 nudt12 LOC113579999 LOC113579999 ENSEEEP00000017001 ENSEEEP00000017001 ttc38 ttc38 ENSEEEP00000016690 ENSEEEP00000016690 elac1 elac1 rpp40 rpp40 ago4 ago4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpp14Uncharacterized protein. (124 aa)
EXOGUncharacterized protein. (355 aa)
LOC113578373Argonaute RISC catalytic component 3b; Belongs to the argonaute family. (859 aa)
AngRNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (156 aa)
pop5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (171 aa)
zc3h12bZinc finger CCCH-type containing 12B. (870 aa)
LOC113569971Deoxyribonuclease I-like 1. (329 aa)
dis3Uncharacterized protein; Belongs to the RNR ribonuclease family. (948 aa)
ENDOVEndonuclease V. (238 aa)
DNA2DNA replication helicase/nuclease 2. (1002 aa)
LOC113589972XendoU domain-containing protein. (307 aa)
dclre1cDNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (683 aa)
mrpl44Uncharacterized protein. (334 aa)
tatdn1Uncharacterized protein. (316 aa)
ENSEEEP00000007004Uncharacterized protein. (286 aa)
rpp38Ribonuclease P/MRP 38 subunit. (260 aa)
rnaseh2aRibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (249 aa)
LOC113568250RAD51 paralog C. (260 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (312 aa)
ern1Uncharacterized protein. (1020 aa)
ENSEEEP00000001936RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (134 aa)
dffbDNA fragmentation factor, beta polypeptide (caspase-activated DNase). (333 aa)
LOC113569619Uncharacterized protein. (202 aa)
ENSEEEP00000001158RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (152 aa)
LOC113568197Uncharacterized protein. (268 aa)
piwil1Uncharacterized protein; Belongs to the argonaute family. (858 aa)
zranb3Zinc finger, RAN-binding domain containing 3. (1057 aa)
dbr1Debranching RNA lariats 1. (560 aa)
rcl1Uncharacterized protein. (373 aa)
elac2ElaC ribonuclease Z 2. (837 aa)
LOC113580343C3H1-type domain-containing protein. (888 aa)
LOC113571916Uncharacterized protein. (372 aa)
mus81MUS81 structure-specific endonuclease subunit. (615 aa)
rexo4Exonuclease domain-containing protein. (432 aa)
dnase1Deoxyribonuclease; Belongs to the DNase I family. (280 aa)
ENSEEEP00000043756XPGI domain-containing protein. (341 aa)
endogEndonuclease. (308 aa)
Piwil2Piwi domain-containing protein. (288 aa)
ago2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (864 aa)
tsen54tRNA_int_end_N2 domain-containing protein. (520 aa)
peloProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (386 aa)
dnase2bUncharacterized protein. (350 aa)
tsen34tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (326 aa)
fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1005 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (567 aa)
droshaUncharacterized protein. (1332 aa)
ENSEEEP00000050384Si:dkey-243k1.3. (273 aa)
ENSEEEP00000050839Metallophos domain-containing protein. (106 aa)
zc3h12aC3H1-type domain-containing protein. (598 aa)
eme1Essential meiotic structure-specific endonuclease 1. (550 aa)
LOC113569782Uncharacterized protein; Belongs to the RNase T2 family. (263 aa)
LOC113577337Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (263 aa)
ENSEEEP00000039119Uncharacterized protein. (260 aa)
LOC113567770Uncharacterized protein. (591 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1085 aa)
LOC113583536Argonaute RISC catalytic component 1; Belongs to the argonaute family. (864 aa)
LOC113583535Argonaute RISC catalytic component 3a; Belongs to the argonaute family. (818 aa)
LOC113572557XendoU domain-containing protein. (289 aa)
smg6SMG6 nonsense mediated mRNA decay factor. (1575 aa)
ankle1Zgc:85936. (862 aa)
ENSEEEP00000035317Zgc:165656. (272 aa)
ENSEEEP00000035283Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (118 aa)
LOC113574523Uncharacterized protein. (165 aa)
rbbp8SAE2 domain-containing protein. (131 aa)
LOC113580907Endoplasmic reticulum to nucleus signaling 2. (876 aa)
nob1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (438 aa)
rnasekUncharacterized protein. (101 aa)
LOC113581116Deoxyribonuclease; Belongs to the DNase I family. (294 aa)
LOC113576618Ribonuclease P and MRP subunit p25, b. (179 aa)
LOC113590030Uncharacterized protein. (347 aa)
bivmUncharacterized protein. (505 aa)
dicer1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1876 aa)
LOC113586234C3H1-type domain-containing protein. (589 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
ridaUncharacterized protein. (136 aa)
pop1POP1 homolog, ribonuclease P/MRP subunit. (889 aa)
rpp30Uncharacterized protein. (266 aa)
tsen2tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (472 aa)
ENSEEEP00000029089Uncharacterized protein. (177 aa)
LOC113589524RECA_2 domain-containing protein. (121 aa)
DNASE1L3Endo/exonuclease/phosphatase domain-containing protein. (338 aa)
prorpPRORP domain-containing protein. (577 aa)
ybeyUncharacterized protein. (169 aa)
ENSEEEP00000027215XPGN domain-containing protein. (302 aa)
Ercc5XPGI domain-containing protein. (396 aa)
LACTB2Lactamase_B domain-containing protein. (286 aa)
snd1Uncharacterized protein. (776 aa)
tsnUncharacterized protein. (227 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
mblac1Lactamase_B domain-containing protein. (224 aa)
LOC113580795Uncharacterized protein. (101 aa)
LOC113568050Uncharacterized protein. (308 aa)
endouEndonuclease, polyU-specific. (350 aa)
ercc4ERCC4 domain-containing protein. (899 aa)
cpsf3Uncharacterized protein. (691 aa)
LOC113584053Endonuclease, polyU-specific 2. (278 aa)
LOC113578936Uncharacterized protein. (296 aa)
rnaseh1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (283 aa)
exo1Exonuclease 1. (771 aa)
ENSEEEP00000019655RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (148 aa)
rnaset2Uncharacterized protein; Belongs to the RNase T2 family. (245 aa)
nudt12Uncharacterized protein. (442 aa)
LOC113579999Tudor domain-containing protein. (184 aa)
ENSEEEP00000017001Endonuclease_NS domain-containing protein. (171 aa)
ttc38Uncharacterized protein. (483 aa)
ENSEEEP00000016690Phospholipase D family, member 6. (207 aa)
elac1Uncharacterized protein. (439 aa)
rpp40Uncharacterized protein. (360 aa)
ago4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (882 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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