STRINGSTRING
LOC113579647 LOC113579647 helb helb XRCC2 XRCC2 pold2 pold2 dmap1 dmap1 dnmt1 dnmt1 TEX264 TEX264 mms22l mms22l rfc5 rfc5 LOC113585360 LOC113585360 pola2 pola2 rfc3 rfc3 rpa3 rpa3 mre11 mre11 pif1 pif1 Wdhd1 Wdhd1 LOC113589524 LOC113589524 tipin tipin DONSON DONSON primpol primpol zranb3 zranb3 LOC113584712 LOC113584712 rpa1 rpa1 pold1 pold1 rfc4 rfc4 LOC113568250 LOC113568250 pold3 pold3 pold4 pold4 hmces hmces chek1 chek1 LOC113571529 LOC113571529 rad51d rad51d rfc2 rfc2 uhrf1 uhrf1 prim1 prim1 rfc1 rfc1 mcm10 mcm10 xrcc3 xrcc3 pola1 pola1 timeless timeless smarcal1 smarcal1 tonsl tonsl prpf19 prpf19 ENSEEEP00000050839 ENSEEEP00000050839 LOC113569669 LOC113569669 rad18 rad18 polh polh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC113579647ETAA1, ATR kinase activator. (776 aa)
helbHelicase (DNA) B. (1009 aa)
XRCC2RECA_2 domain-containing protein. (302 aa)
pold2Uncharacterized protein. (469 aa)
dmap1SANT domain-containing protein. (473 aa)
dnmt1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1489 aa)
TEX264Uncharacterized protein. (310 aa)
mms22lUncharacterized protein. (1240 aa)
rfc5AAA domain-containing protein. (363 aa)
LOC113585360Uncharacterized protein. (555 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa)
rfc3AAA domain-containing protein. (356 aa)
rpa3Uncharacterized protein. (122 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (636 aa)
Wdhd1WD_REPEATS_REGION domain-containing protein. (311 aa)
LOC113589524RECA_2 domain-containing protein. (121 aa)
tipinTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (305 aa)
DONSONUncharacterized protein. (570 aa)
primpolPrimase and polymerase (DNA-directed). (519 aa)
zranb3Zinc finger, RAN-binding domain containing 3. (1057 aa)
LOC113584712Uncharacterized protein. (812 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (624 aa)
pold1DNA polymerase. (1061 aa)
rfc4AAA domain-containing protein. (357 aa)
LOC113568250RAD51 paralog C. (260 aa)
pold3Uncharacterized protein. (462 aa)
pold4Uncharacterized protein. (109 aa)
hmcesAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (362 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (470 aa)
LOC113571529DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa)
rad51dRECA_2 domain-containing protein. (338 aa)
rfc2AAA domain-containing protein. (369 aa)
uhrf1Ubiquitin-like with PHD and ring finger domains 1. (784 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (422 aa)
rfc1Replication factor C subunit 1. (1124 aa)
mcm10Mcm10 domain-containing protein. (838 aa)
xrcc3RECA_2 domain-containing protein. (355 aa)
pola1DNA polymerase. (1321 aa)
timelessTimeless circadian clock. (1201 aa)
smarcal1Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (884 aa)
tonslTonsoku-like, DNA repair protein. (1431 aa)
prpf19Pre-mRNA processing factor 19. (499 aa)
ENSEEEP00000050839Metallophos domain-containing protein. (106 aa)
LOC113569669Uncharacterized protein. (306 aa)
rad18RAD18 E3 ubiquitin protein ligase. (459 aa)
polhPolymerase (DNA directed), eta. (700 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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