47 items (Electrophorus electricus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113579647	ETAA1, ATR kinase activator. (776 aa)
	helb	Helicase (DNA) B. (1009 aa)
	XRCC2	RECA_2 domain-containing protein. (302 aa)
	pold2	Uncharacterized protein. (469 aa)
	dmap1	SANT domain-containing protein. (473 aa)
	dnmt1	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1489 aa)
	TEX264	Uncharacterized protein. (310 aa)
	mms22l	Uncharacterized protein. (1240 aa)
	rfc5	AAA domain-containing protein. (363 aa)
	LOC113585360	Uncharacterized protein. (555 aa)
	pola2	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa)
	rfc3	AAA domain-containing protein. (356 aa)
	rpa3	Uncharacterized protein. (122 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
	pif1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (636 aa)
	Wdhd1	WD_REPEATS_REGION domain-containing protein. (311 aa)
	LOC113589524	RECA_2 domain-containing protein. (121 aa)
	tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (305 aa)
	DONSON	Uncharacterized protein. (570 aa)
	primpol	Primase and polymerase (DNA-directed). (519 aa)
	zranb3	Zinc finger, RAN-binding domain containing 3. (1057 aa)
	LOC113584712	Uncharacterized protein. (812 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (624 aa)
	pold1	DNA polymerase. (1061 aa)
	rfc4	AAA domain-containing protein. (357 aa)
	LOC113568250	RAD51 paralog C. (260 aa)
	pold3	Uncharacterized protein. (462 aa)
	pold4	Uncharacterized protein. (109 aa)
	hmces	Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (362 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (470 aa)
	LOC113571529	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa)
	rad51d	RECA_2 domain-containing protein. (338 aa)
	rfc2	AAA domain-containing protein. (369 aa)
	uhrf1	Ubiquitin-like with PHD and ring finger domains 1. (784 aa)
	prim1	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (422 aa)
	rfc1	Replication factor C subunit 1. (1124 aa)
	mcm10	Mcm10 domain-containing protein. (838 aa)
	xrcc3	RECA_2 domain-containing protein. (355 aa)
	pola1	DNA polymerase. (1321 aa)
	timeless	Timeless circadian clock. (1201 aa)
	smarcal1	Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (884 aa)
	tonsl	Tonsoku-like, DNA repair protein. (1431 aa)
	prpf19	Pre-mRNA processing factor 19. (499 aa)
	ENSEEEP00000050839	Metallophos domain-containing protein. (106 aa)
	LOC113569669	Uncharacterized protein. (306 aa)
	rad18	RAD18 E3 ubiquitin protein ligase. (459 aa)
	polh	Polymerase (DNA directed), eta. (700 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DONSON	LOC113571529	ENSEEEP00000029920	ENSEEEP00000008213	Uncharacterized protein.	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	0.707
DONSON	Wdhd1	ENSEEEP00000029920	ENSEEEP00000026106	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.433
DONSON	mcm10	ENSEEEP00000029920	ENSEEEP00000015077	Uncharacterized protein.	Mcm10 domain-containing protein.	0.461
DONSON	pola2	ENSEEEP00000029920	ENSEEEP00000022425	Uncharacterized protein.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.492
DONSON	pold2	ENSEEEP00000029920	ENSEEEP00000040348	Uncharacterized protein.	Uncharacterized protein.	0.651
DONSON	primpol	ENSEEEP00000029920	ENSEEEP00000032384	Uncharacterized protein.	Primase and polymerase (DNA-directed).	0.477
DONSON	rfc3	ENSEEEP00000029920	ENSEEEP00000022821	Uncharacterized protein.	AAA domain-containing protein.	0.431
DONSON	rfc4	ENSEEEP00000029920	ENSEEEP00000002918	Uncharacterized protein.	AAA domain-containing protein.	0.623
ENSEEEP00000050839	LOC113568250	ENSEEEP00000050839	ENSEEEP00000004244	Metallophos domain-containing protein.	RAD51 paralog C.	0.743
ENSEEEP00000050839	LOC113571529	ENSEEEP00000050839	ENSEEEP00000008213	Metallophos domain-containing protein.	DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.	0.591
ENSEEEP00000050839	LOC113589524	ENSEEEP00000050839	ENSEEEP00000028964	Metallophos domain-containing protein.	RECA_2 domain-containing protein.	0.743
ENSEEEP00000050839	XRCC2	ENSEEEP00000050839	ENSEEEP00000039680	Metallophos domain-containing protein.	RECA_2 domain-containing protein.	0.729
ENSEEEP00000050839	chek1	ENSEEEP00000050839	ENSEEEP00000008052	Metallophos domain-containing protein.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.706
ENSEEEP00000050839	pif1	ENSEEEP00000050839	ENSEEEP00000024943	Metallophos domain-containing protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.717
ENSEEEP00000050839	pola1	ENSEEEP00000050839	ENSEEEP00000016683	Metallophos domain-containing protein.	DNA polymerase.	0.505
ENSEEEP00000050839	pold1	ENSEEEP00000050839	ENSEEEP00000002302	Metallophos domain-containing protein.	DNA polymerase.	0.687
ENSEEEP00000050839	pold2	ENSEEEP00000050839	ENSEEEP00000040348	Metallophos domain-containing protein.	Uncharacterized protein.	0.409
ENSEEEP00000050839	polh	ENSEEEP00000050839	ENSEEEP00000018380	Metallophos domain-containing protein.	Polymerase (DNA directed), eta.	0.617
ENSEEEP00000050839	rad18	ENSEEEP00000050839	ENSEEEP00000052166	Metallophos domain-containing protein.	RAD18 E3 ubiquitin protein ligase.	0.499
ENSEEEP00000050839	rad51d	ENSEEEP00000050839	ENSEEEP00000008581	Metallophos domain-containing protein.	RECA_2 domain-containing protein.	0.845