16 items (Electrophorus electricus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	telo2	TEL2, telomere maintenance 2, homolog (S. cerevisiae). (850 aa)
	gar1	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (202 aa)
	LOC113591471	Prostaglandin E synthase 3b (cytosolic). (159 aa)
	dkc1	PUA domain-containing protein. (525 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1181 aa)
	nop10	Uncharacterized protein. (64 aa)
	tert	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1062 aa)
	ENSEEEP00000034928	Uncharacterized protein. (435 aa)
	wrap53	WD repeat containing, antisense to TP53. (519 aa)
	pinx1	PIN2 (TERF1) interacting telomerase inhibitor 1. (181 aa)
	pot1	Protection of telomeres 1 homolog. (767 aa)
	nhp2	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (624 aa)
	LOC113569058	AAA_23 domain-containing protein. (469 aa)
	ENSEEEP00000007003	AAA_23 domain-containing protein. (53 aa)
	ptges3	CS domain-containing protein. (159 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000007003	pot1	ENSEEEP00000007003	ENSEEEP00000018754	AAA_23 domain-containing protein.	Protection of telomeres 1 homolog.	0.447
ENSEEEP00000007003	rpa1	ENSEEEP00000007003	ENSEEEP00000001444	AAA_23 domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.724
ENSEEEP00000007003	tert	ENSEEEP00000007003	ENSEEEP00000035184	AAA_23 domain-containing protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.524
ENSEEEP00000034928	dkc1	ENSEEEP00000034928	ENSEEEP00000043322	Uncharacterized protein.	PUA domain-containing protein.	0.650
ENSEEEP00000034928	gar1	ENSEEEP00000034928	ENSEEEP00000014586	Uncharacterized protein.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.628
ENSEEEP00000034928	nhp2	ENSEEEP00000034928	ENSEEEP00000014933	Uncharacterized protein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.649
ENSEEEP00000034928	nop10	ENSEEEP00000034928	ENSEEEP00000011927	Uncharacterized protein.	Uncharacterized protein.	0.650
ENSEEEP00000034928	pot1	ENSEEEP00000034928	ENSEEEP00000018754	Uncharacterized protein.	Protection of telomeres 1 homolog.	0.985
ENSEEEP00000034928	rpa1	ENSEEEP00000034928	ENSEEEP00000001444	Uncharacterized protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.588
ENSEEEP00000034928	tert	ENSEEEP00000034928	ENSEEEP00000035184	Uncharacterized protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.934
ENSEEEP00000034928	wrap53	ENSEEEP00000034928	ENSEEEP00000032712	Uncharacterized protein.	WD repeat containing, antisense to TP53.	0.561
LOC113569058	pot1	ENSEEEP00000005699	ENSEEEP00000018754	AAA_23 domain-containing protein.	Protection of telomeres 1 homolog.	0.447
LOC113569058	rad50	ENSEEEP00000005699	ENSEEEP00000013894	AAA_23 domain-containing protein.	RAD50 homolog, double strand break repair protein.	0.958
LOC113569058	rpa1	ENSEEEP00000005699	ENSEEEP00000001444	AAA_23 domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.724
LOC113569058	tert	ENSEEEP00000005699	ENSEEEP00000035184	AAA_23 domain-containing protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.524
LOC113591471	ptges3	ENSEEEP00000043696	ENSEEEP00000009105	Prostaglandin E synthase 3b (cytosolic).	CS domain-containing protein.	0.901
LOC113591471	tert	ENSEEEP00000043696	ENSEEEP00000035184	Prostaglandin E synthase 3b (cytosolic).	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.586
dkc1	ENSEEEP00000034928	ENSEEEP00000043322	ENSEEEP00000034928	PUA domain-containing protein.	Uncharacterized protein.	0.650
dkc1	gar1	ENSEEEP00000043322	ENSEEEP00000014586	PUA domain-containing protein.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.999
dkc1	nhp2	ENSEEEP00000043322	ENSEEEP00000014933	PUA domain-containing protein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.999