STRINGSTRING
cdca7l cdca7l ENSEEEP00000006834 ENSEEEP00000006834 LOC113575331 LOC113575331 zmpste24 zmpste24 LOC113589927 LOC113589927 LOC113575351 LOC113575351 ercc6 ercc6 rad1 rad1 mdm2 mdm2 fancd2 fancd2 sfrp2 sfrp2 gadd45b gadd45b rhno1 rhno1 dcun1d3 dcun1d3 ENSEEEP00000051054 ENSEEEP00000051054 ect2 ect2 Mrnip Mrnip rnf168 rnf168 ENSEEEP00000050260 ENSEEEP00000050260 LOC113583726 LOC113583726 LOC113589335 LOC113589335 LOC113590492 LOC113590492 LOC113571516 LOC113571516 LOC113573801 LOC113573801 bax bax stk11 stk11 tank tank LOC113588689 LOC113588689 bard1 bard1 chek2 chek2 LOC113576847 LOC113576847 mfsd11 mfsd11 xrcc4 xrcc4 xrcc5 xrcc5 uimc1 uimc1 brcc3 brcc3 fbxo4 fbxo4 ercc1 ercc1 XRCC2 XRCC2 ticrr ticrr LOC113578802 LOC113578802 smpd1 smpd1 Cunh10orf90 Cunh10orf90 msh2 msh2 sirt1 sirt1 men1 men1 blm blm LOC113579116 LOC113579116 rad51ap1 rad51ap1 atr atr ENSEEEP00000032310 ENSEEEP00000032310 rad9a rad9a ENSEEEP00000031234 ENSEEEP00000031234 kars1 kars1 itgb6 itgb6 abraxas1 abraxas1 babam1 babam1 rnf8 rnf8 ino80 ino80 lig4 lig4 brat1 brat1 ercc8 ercc8 xrcc6 xrcc6 ENSEEEP00000023290 ENSEEEP00000023290 inip inip spidr spidr bcl2 bcl2 ints3 ints3 LOC113582267 LOC113582267 PTPRC PTPRC rad51 rad51 kdm1a kdm1a abcg5 abcg5 topbp1 topbp1 LOC113573821 LOC113573821 LOC113580065 LOC113580065 babam2 babam2 Cop1 Cop1 cdca7 cdca7 ENSEEEP00000009645 ENSEEEP00000009645 LOC113581577 LOC113581577
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdca7lCell division cycle associated 7b. (425 aa)
ENSEEEP00000006834Uncharacterized protein. (110 aa)
LOC113575331Nucleic acid binding protein 1b. (203 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (474 aa)
LOC113589927Uncharacterized protein. (414 aa)
LOC113575351Uncharacterized protein. (215 aa)
ercc6Excision repair cross-complementation group 6. (1398 aa)
rad1Uncharacterized protein. (279 aa)
mdm2Uncharacterized protein. (512 aa)
fancd2FA complementation group D2. (1261 aa)
sfrp2Uncharacterized protein. (291 aa)
gadd45bRibosomal_L7Ae domain-containing protein. (162 aa)
rhno1Uncharacterized protein. (308 aa)
dcun1d3DCN1-like protein. (325 aa)
ENSEEEP00000051054Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (307 aa)
ect2Epithelial cell transforming 2. (975 aa)
MrnipUncharacterized protein. (88 aa)
rnf168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (471 aa)
ENSEEEP00000050260Deoxyribonuclease 1 like 4, tandem duplicate 2. (243 aa)
LOC113583726Deoxyribonuclease; Belongs to the DNase I family. (267 aa)
LOC113589335Ribosomal_L7Ae domain-containing protein. (159 aa)
LOC113590492Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
LOC113571516Uncharacterized protein. (221 aa)
LOC113573801Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
baxBCL2 associated X, apoptosis regulator a. (192 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (444 aa)
tankTBD domain-containing protein. (343 aa)
LOC113588689Nucleic acid binding protein 2. (156 aa)
bard1BRCA1 associated RING domain 1. (689 aa)
chek2Uncharacterized protein. (526 aa)
LOC113576847RING-type domain-containing protein. (995 aa)
mfsd11Major facilitator superfamily domain containing 11. (455 aa)
xrcc4Uncharacterized protein. (343 aa)
xrcc5Ku domain-containing protein. (740 aa)
uimc1RAP80_UIM domain-containing protein. (953 aa)
brcc3BRCA1/BRCA2-containing complex, subunit 3. (269 aa)
fbxo4F-box protein 4. (371 aa)
ercc1Uncharacterized protein. (346 aa)
XRCC2RECA_2 domain-containing protein. (302 aa)
ticrrTreslin_N domain-containing protein. (1771 aa)
LOC113578802Uncharacterized protein. (204 aa)
smpd1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (604 aa)
Cunh10orf90Uncharacterized protein. (438 aa)
msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (939 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (729 aa)
men1Uncharacterized protein. (615 aa)
blmBLM RecQ like helicase. (1281 aa)
LOC113579116DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1454 aa)
rad51ap1RAD51_interact domain-containing protein. (230 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2627 aa)
ENSEEEP00000032310ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (386 aa)
ENSEEEP00000031234ELK1, member of ETS oncogene family. (423 aa)
kars1Lysine--tRNA ligase. (608 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (764 aa)
abraxas1MPN domain-containing protein. (419 aa)
babam1Uncharacterized protein. (359 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (484 aa)
ino80Uncharacterized protein. (1128 aa)
lig4DNA ligase. (909 aa)
brat1BRCA1-associated ATM activator 1. (757 aa)
ercc8WD_REPEATS_REGION domain-containing protein. (400 aa)
xrcc6Uncharacterized protein. (627 aa)
ENSEEEP00000023290RAD9 checkpoint clamp component B. (181 aa)
inipUncharacterized protein. (102 aa)
spidrDUF4503 domain-containing protein. (573 aa)
bcl2BH4_2 domain-containing protein. (223 aa)
ints3Integrator complex subunit 3. (1015 aa)
LOC113582267Breast cancer 2, early onset. (2391 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (720 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (859 aa)
abcg5ATP-binding cassette, sub-family G (WHITE), member 5. (661 aa)
topbp1DNA topoisomerase II binding protein 1. (1479 aa)
LOC113573821BCL2, apoptosis regulator a. (209 aa)
LOC113580065Protein kinase domain-containing protein. (462 aa)
babam2Uncharacterized protein. (442 aa)
Cop1COP1, E3 ubiquitin ligase. (430 aa)
cdca7zf-4CXXC_R1 domain-containing protein. (406 aa)
ENSEEEP00000009645Pkinase_Tyr domain-containing protein. (238 aa)
LOC113581577Uncharacterized protein. (355 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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