(13 nodes) Positive regulation of heart rate network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113570980	Adrenoceptor alpha 1Aa. (497 aa)
	ENSEEEP00000002117	Endothelin 1. (99 aa)
	LOC113568456	G_PROTEIN_RECEP_F1_2 domain-containing protein. (468 aa)
	ENSEEEP00000019963	Uncharacterized protein. (132 aa)
	adra1d	G_PROTEIN_RECEP_F1_2 domain-containing protein. (497 aa)
	gch1	GTP cyclohydrolase 1. (243 aa)
	LOC113577744	Uncharacterized protein. (179 aa)
	scn3b	Sodium channel, voltage-gated, type III, beta. (239 aa)
	LOC113572825	GTP cyclohydrolase 2. (222 aa)
	ENSEEEP00000037399	Ion_trans domain-containing protein; Belongs to the potassium channel family. (375 aa)
	adm2	Uncharacterized protein. (179 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (460 aa)
	adra1b	Adrenoceptor alpha 1Ba. (456 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000002117	LOC113568456	ENSEEEP00000002117	ENSEEEP00000014559	Endothelin 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.530
ENSEEEP00000002117	LOC113570980	ENSEEEP00000002117	ENSEEEP00000020783	Endothelin 1.	Adrenoceptor alpha 1Aa.	0.667
ENSEEEP00000002117	adra1b	ENSEEEP00000002117	ENSEEEP00000043763	Endothelin 1.	Adrenoceptor alpha 1Ba.	0.530
ENSEEEP00000002117	adra1d	ENSEEEP00000002117	ENSEEEP00000024942	Endothelin 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.530
ENSEEEP00000019963	adm2	ENSEEEP00000019963	ENSEEEP00000038003	Uncharacterized protein.	Uncharacterized protein.	0.544
KCNQ1	scn3b	ENSEEEP00000039495	ENSEEEP00000033933	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	Sodium channel, voltage-gated, type III, beta.	0.497
LOC113568456	ENSEEEP00000002117	ENSEEEP00000014559	ENSEEEP00000002117	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Endothelin 1.	0.530
LOC113568456	LOC113570980	ENSEEEP00000014559	ENSEEEP00000020783	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Adrenoceptor alpha 1Aa.	0.477
LOC113570980	ENSEEEP00000002117	ENSEEEP00000020783	ENSEEEP00000002117	Adrenoceptor alpha 1Aa.	Endothelin 1.	0.667
LOC113570980	LOC113568456	ENSEEEP00000020783	ENSEEEP00000014559	Adrenoceptor alpha 1Aa.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.477
LOC113570980	adra1b	ENSEEEP00000020783	ENSEEEP00000043763	Adrenoceptor alpha 1Aa.	Adrenoceptor alpha 1Ba.	0.474
LOC113570980	adra1d	ENSEEEP00000020783	ENSEEEP00000024942	Adrenoceptor alpha 1Aa.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.469
LOC113577744	adm2	ENSEEEP00000031289	ENSEEEP00000038003	Uncharacterized protein.	Uncharacterized protein.	0.544
adm2	ENSEEEP00000019963	ENSEEEP00000038003	ENSEEEP00000019963	Uncharacterized protein.	Uncharacterized protein.	0.544
adm2	LOC113577744	ENSEEEP00000038003	ENSEEEP00000031289	Uncharacterized protein.	Uncharacterized protein.	0.544
adra1b	ENSEEEP00000002117	ENSEEEP00000043763	ENSEEEP00000002117	Adrenoceptor alpha 1Ba.	Endothelin 1.	0.530
adra1b	LOC113570980	ENSEEEP00000043763	ENSEEEP00000020783	Adrenoceptor alpha 1Ba.	Adrenoceptor alpha 1Aa.	0.474
adra1d	ENSEEEP00000002117	ENSEEEP00000024942	ENSEEEP00000002117	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Endothelin 1.	0.530
adra1d	LOC113570980	ENSEEEP00000024942	ENSEEEP00000020783	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Adrenoceptor alpha 1Aa.	0.469
scn3b	KCNQ1	ENSEEEP00000033933	ENSEEEP00000039495	Sodium channel, voltage-gated, type III, beta.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.497