(47 nodes) Negative regulation of autophagy network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tspo	Uncharacterized protein. (161 aa)
	foxk1	Forkhead box K1. (404 aa)
	ENSEEEP00000001078	Uncharacterized protein. (75 aa)
	klhl22	Kelch-like family member 22. (585 aa)
	LOC113569846	Carboxypeptidase; Belongs to the peptidase S10 family. (329 aa)
	cptp	GLTP domain-containing protein. (211 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2512 aa)
	ENSEEEP00000003759	Uncharacterized protein. (76 aa)
	pink1	Protein kinase domain-containing protein. (579 aa)
	scfd1	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (629 aa)
	bmf	Uncharacterized protein. (156 aa)
	rubcn	RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein. (836 aa)
	Tsc1	Uncharacterized protein. (383 aa)
	LOC113582109	ApaG domain-containing protein. (380 aa)
	LOC113590071	Uncharacterized protein. (608 aa)
	LOC113573821	BCL2, apoptosis regulator a. (209 aa)
	ENSEEEP00000015130	Forkhead box K2. (395 aa)
	ctsa	Carboxypeptidase; Belongs to the peptidase S10 family. (517 aa)
	ENSEEEP00000018338	Fasciculation and elongation protein zeta 1 (zygin I). (402 aa)
	Fez1	Fasciculation and elongation protein zeta 1 (zygin I). (164 aa)
	dap	Uncharacterized protein. (105 aa)
	mtmr9	Myotubularin phosphatase domain-containing protein. (554 aa)
	bcl2	BH4_2 domain-containing protein. (223 aa)
	ENSEEEP00000021146	Leptin a. (173 aa)
	tmem39a	Uncharacterized protein. (567 aa)
	phf23	PHD domain-containing protein. (320 aa)
	smg1	SMG1 phosphatidylinositol 3-kinase-related kinase; Belongs to the PI3/PI4-kinase family. (3631 aa)
	htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (492 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (385 aa)
	nrbp2	Nuclear receptor binding protein 2a. (399 aa)
	LOC113570273	PHD domain-containing protein. (305 aa)
	LOC113583491	Forkhead box K2. (586 aa)
	il10	Uncharacterized protein. (180 aa)
	tsc2	TSC complex subunit 2. (1801 aa)
	LOC113580905	Smith-Magenis syndrome chromosome region, candidate 8b. (797 aa)
	lepr	Leptin receptor. (1072 aa)
	ENSEEEP00000042802	Uncharacterized protein. (380 aa)
	LOC113589222	Myotubularin phosphatase domain-containing protein. (579 aa)
	LOC113577952	Death associated protein 1b. (113 aa)
	clec16a	C-type lectin domain containing 16A. (1034 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2557 aa)
	wdr6	WD_REPEATS_REGION domain-containing protein. (1239 aa)
	tmem39b	Uncharacterized protein. (486 aa)
	LOC113584826	Leucine zipper, putative tumor suppressor 1. (578 aa)
	LOC113582955	Uncharacterized protein. (365 aa)
	LOC113583120	Si:dkey-288i20.2. (356 aa)
	LOC113569737	Polymerase (DNA-directed), delta interacting protein 2. (390 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000021146	LOC113573821	ENSEEEP00000021146	ENSEEEP00000014809	Leptin a.	BCL2, apoptosis regulator a.	0.410
ENSEEEP00000021146	bcl2	ENSEEEP00000021146	ENSEEEP00000020091	Leptin a.	BH4_2 domain-containing protein.	0.410
ENSEEEP00000021146	il10	ENSEEEP00000021146	ENSEEEP00000037779	Leptin a.	Uncharacterized protein.	0.442
ENSEEEP00000021146	lepr	ENSEEEP00000021146	ENSEEEP00000041944	Leptin a.	Leptin receptor.	0.853
ENSEEEP00000042802	mtor	ENSEEEP00000042802	ENSEEEP00000045364	Uncharacterized protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.891
ENSEEEP00000042802	pink1	ENSEEEP00000042802	ENSEEEP00000003966	Uncharacterized protein.	Protein kinase domain-containing protein.	0.507
ENSEEEP00000042802	smg1	ENSEEEP00000042802	ENSEEEP00000028880	Uncharacterized protein.	SMG1 phosphatidylinositol 3-kinase-related kinase; Belongs to the PI3/PI4-kinase family.	0.657
ENSEEEP00000042802	tsc2	ENSEEEP00000042802	ENSEEEP00000038113	Uncharacterized protein.	TSC complex subunit 2.	0.972
LOC113573821	ENSEEEP00000021146	ENSEEEP00000014809	ENSEEEP00000021146	BCL2, apoptosis regulator a.	Leptin a.	0.410
LOC113573821	bmf	ENSEEEP00000014809	ENSEEEP00000004738	BCL2, apoptosis regulator a.	Uncharacterized protein.	0.816
LOC113589222	LOC113590071	ENSEEEP00000044405	ENSEEEP00000013745	Myotubularin phosphatase domain-containing protein.	Uncharacterized protein.	0.823
LOC113590071	LOC113589222	ENSEEEP00000013745	ENSEEEP00000044405	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.823
LOC113590071	mtmr9	ENSEEEP00000013745	ENSEEEP00000019457	Uncharacterized protein.	Myotubularin phosphatase domain-containing protein.	0.849
Tsc1	mtor	ENSEEEP00000007351	ENSEEEP00000045364	Uncharacterized protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.891
Tsc1	pink1	ENSEEEP00000007351	ENSEEEP00000003966	Uncharacterized protein.	Protein kinase domain-containing protein.	0.507
Tsc1	smg1	ENSEEEP00000007351	ENSEEEP00000028880	Uncharacterized protein.	SMG1 phosphatidylinositol 3-kinase-related kinase; Belongs to the PI3/PI4-kinase family.	0.657
Tsc1	tsc2	ENSEEEP00000007351	ENSEEEP00000038113	Uncharacterized protein.	TSC complex subunit 2.	0.972
bcl2	ENSEEEP00000021146	ENSEEEP00000020091	ENSEEEP00000021146	BH4_2 domain-containing protein.	Leptin a.	0.410
bcl2	bmf	ENSEEEP00000020091	ENSEEEP00000004738	BH4_2 domain-containing protein.	Uncharacterized protein.	0.816
bmf	LOC113573821	ENSEEEP00000004738	ENSEEEP00000014809	Uncharacterized protein.	BCL2, apoptosis regulator a.	0.816