(31 nodes) Regulation of centrosome duplication network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stil	Scl/tal1 interrupting locus. (1203 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (729 aa)
	Cunh10orf90	Uncharacterized protein. (438 aa)
	xpo1	Importin N-terminal domain-containing protein. (1087 aa)
	fbxw5	Uncharacterized protein. (616 aa)
	ENSEEEP00000043756	XPGI domain-containing protein. (341 aa)
	LOC113583451	Nucleophosmin/nucleoplasmin, 2b. (160 aa)
	trim37	Tripartite motif containing 37. (743 aa)
	ccnf	Cyclin F; Belongs to the cyclin family. (760 aa)
	spice1	Spindle and centriole associated protein 1. (604 aa)
	mdm1	Mdm1 nuclear protein homolog (mouse). (656 aa)
	cep131	Centrosomal protein 131. (1105 aa)
	LOC113588724	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (793 aa)
	LOC113588736	Uncharacterized protein. (303 aa)
	LOC113578723	Cysteine and histidine-rich domain (CHORD) containing 1a. (337 aa)
	ENSEEEP00000007029	Cnn_1N domain-containing protein. (178 aa)
	ccdc84	Coiled-coil domain containing 84. (349 aa)
	LOC113582158	Exportin 1 (CRM1 homolog, yeast) b. (1056 aa)
	LOC113587682	Uncharacterized protein. (354 aa)
	ENSEEEP00000011885	RRM domain-containing protein. (108 aa)
	plk4	Uncharacterized protein. (923 aa)
	ppp1r35	PPP1R35_C domain-containing protein. (282 aa)
	pdcd6ip	BRO1 domain-containing protein. (876 aa)
	xrcc3	RECA_2 domain-containing protein. (355 aa)
	ENSEEEP00000016355	Uncharacterized protein. (209 aa)
	cep120	Uncharacterized protein. (982 aa)
	nat10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1057 aa)
	sass6	Uncharacterized protein. (647 aa)
	LOC113581658	Uncharacterized protein. (340 aa)
	cep76	CEP76-C2 domain-containing protein. (664 aa)
	ENSEEEP00000033785	Nucleophosmin 1b. (238 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000007029	plk4	ENSEEEP00000007029	ENSEEEP00000012632	Cnn_1N domain-containing protein.	Uncharacterized protein.	0.477
ENSEEEP00000043756	sass6	ENSEEEP00000043756	ENSEEEP00000024563	XPGI domain-containing protein.	Uncharacterized protein.	0.451
ENSEEEP00000043756	xrcc3	ENSEEEP00000043756	ENSEEEP00000016330	XPGI domain-containing protein.	RECA_2 domain-containing protein.	0.709
LOC113582158	plk4	ENSEEEP00000010033	ENSEEEP00000012632	Exportin 1 (CRM1 homolog, yeast) b.	Uncharacterized protein.	0.421
LOC113582158	xpo1	ENSEEEP00000010033	ENSEEEP00000036023	Exportin 1 (CRM1 homolog, yeast) b.	Importin N-terminal domain-containing protein.	0.900
LOC113588724	nat10	ENSEEEP00000002023	ENSEEEP00000022126	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.446
LOC113588724	sirt1	ENSEEEP00000002023	ENSEEEP00000035306	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Deacetylase sirtuin-type domain-containing protein.	0.574
cep120	cep131	ENSEEEP00000016624	ENSEEEP00000001946	Uncharacterized protein.	Centrosomal protein 131.	0.414
cep120	cep76	ENSEEEP00000016624	ENSEEEP00000027128	Uncharacterized protein.	CEP76-C2 domain-containing protein.	0.563
cep120	plk4	ENSEEEP00000016624	ENSEEEP00000012632	Uncharacterized protein.	Uncharacterized protein.	0.631
cep120	sass6	ENSEEEP00000016624	ENSEEEP00000024563	Uncharacterized protein.	Uncharacterized protein.	0.454
cep120	spice1	ENSEEEP00000016624	ENSEEEP00000047176	Uncharacterized protein.	Spindle and centriole associated protein 1.	0.694
cep120	stil	ENSEEEP00000016624	ENSEEEP00000032435	Uncharacterized protein.	Scl/tal1 interrupting locus.	0.431
cep131	cep120	ENSEEEP00000001946	ENSEEEP00000016624	Centrosomal protein 131.	Uncharacterized protein.	0.414
cep131	plk4	ENSEEEP00000001946	ENSEEEP00000012632	Centrosomal protein 131.	Uncharacterized protein.	0.634
cep76	cep120	ENSEEEP00000027128	ENSEEEP00000016624	CEP76-C2 domain-containing protein.	Uncharacterized protein.	0.563
cep76	plk4	ENSEEEP00000027128	ENSEEEP00000012632	CEP76-C2 domain-containing protein.	Uncharacterized protein.	0.733
cep76	sass6	ENSEEEP00000027128	ENSEEEP00000024563	CEP76-C2 domain-containing protein.	Uncharacterized protein.	0.442
cep76	stil	ENSEEEP00000027128	ENSEEEP00000032435	CEP76-C2 domain-containing protein.	Scl/tal1 interrupting locus.	0.424
fbxw5	plk4	ENSEEEP00000042658	ENSEEEP00000012632	Uncharacterized protein.	Uncharacterized protein.	0.483