(23 nodes) Translesion synthesis network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113569737	Polymerase (DNA-directed), delta interacting protein 2. (390 aa)
	zbtb1	Uncharacterized protein. (680 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	primpol	Primase and polymerase (DNA-directed). (519 aa)
	dtl	WD_REPEATS_REGION domain-containing protein. (687 aa)
	poli	UmuC domain-containing protein. (737 aa)
	Rev3l	DNA_pol_B domain-containing protein. (304 aa)
	polh	Polymerase (DNA directed), eta. (700 aa)
	sprtn	SprT-like N-terminal domain. (478 aa)
	Polk	Uncharacterized protein. (403 aa)
	polk	Polymerase (DNA directed) kappa. (413 aa)
	LOC113582109	ApaG domain-containing protein. (380 aa)
	rev1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1187 aa)
	pold3	Uncharacterized protein. (462 aa)
	ENSEEEP00000004035	Dpoe2NT domain-containing protein. (82 aa)
	pold1	DNA polymerase. (1061 aa)
	LOC113571395	Polymerase (DNA directed), epsilon 2. (527 aa)
	pold2	Uncharacterized protein. (469 aa)
	pclaf	PAF domain-containing protein. (113 aa)
	LOC113592019	Zgc:136908; Belongs to the AAA ATPase family. (806 aa)
	ENSEEEP00000045589	Poly [ADP-ribose] polymerase. (212 aa)
	ENSEEEP00000045590	WWE domain-containing protein. (655 aa)
	vcp	Uncharacterized protein; Belongs to the AAA ATPase family. (806 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000004035	Polk	ENSEEEP00000004035	ENSEEEP00000007978	Dpoe2NT domain-containing protein.	Uncharacterized protein.	0.536
ENSEEEP00000004035	Rev3l	ENSEEEP00000004035	ENSEEEP00000018397	Dpoe2NT domain-containing protein.	DNA_pol_B domain-containing protein.	0.845
ENSEEEP00000004035	dtl	ENSEEEP00000004035	ENSEEEP00000032505	Dpoe2NT domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.733
ENSEEEP00000004035	pclaf	ENSEEEP00000004035	ENSEEEP00000041804	Dpoe2NT domain-containing protein.	PAF domain-containing protein.	0.560
ENSEEEP00000004035	pcna	ENSEEEP00000004035	ENSEEEP00000028033	Dpoe2NT domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.760
ENSEEEP00000004035	pold1	ENSEEEP00000004035	ENSEEEP00000002302	Dpoe2NT domain-containing protein.	DNA polymerase.	0.921
ENSEEEP00000004035	pold2	ENSEEEP00000004035	ENSEEEP00000040348	Dpoe2NT domain-containing protein.	Uncharacterized protein.	0.856
ENSEEEP00000004035	pold3	ENSEEEP00000004035	ENSEEEP00000005809	Dpoe2NT domain-containing protein.	Uncharacterized protein.	0.525
ENSEEEP00000004035	polh	ENSEEEP00000004035	ENSEEEP00000018380	Dpoe2NT domain-containing protein.	Polymerase (DNA directed), eta.	0.555
ENSEEEP00000004035	poli	ENSEEEP00000004035	ENSEEEP00000019510	Dpoe2NT domain-containing protein.	UmuC domain-containing protein.	0.510
ENSEEEP00000004035	polk	ENSEEEP00000004035	ENSEEEP00000007972	Dpoe2NT domain-containing protein.	Polymerase (DNA directed) kappa.	0.536
ENSEEEP00000004035	rev1	ENSEEEP00000004035	ENSEEEP00000007242	Dpoe2NT domain-containing protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.476
ENSEEEP00000045589	ENSEEEP00000045590	ENSEEEP00000045589	ENSEEEP00000045590	Poly [ADP-ribose] polymerase.	WWE domain-containing protein.	0.854
ENSEEEP00000045590	ENSEEEP00000045589	ENSEEEP00000045590	ENSEEEP00000045589	WWE domain-containing protein.	Poly [ADP-ribose] polymerase.	0.854
LOC113569737	pold2	ENSEEEP00000052608	ENSEEEP00000040348	Polymerase (DNA-directed), delta interacting protein 2.	Uncharacterized protein.	0.431
LOC113569737	primpol	ENSEEEP00000052608	ENSEEEP00000032384	Polymerase (DNA-directed), delta interacting protein 2.	Primase and polymerase (DNA-directed).	0.442
LOC113571395	Polk	ENSEEEP00000000250	ENSEEEP00000007978	Polymerase (DNA directed), epsilon 2.	Uncharacterized protein.	0.536
LOC113571395	Rev3l	ENSEEEP00000000250	ENSEEEP00000018397	Polymerase (DNA directed), epsilon 2.	DNA_pol_B domain-containing protein.	0.896
LOC113571395	dtl	ENSEEEP00000000250	ENSEEEP00000032505	Polymerase (DNA directed), epsilon 2.	WD_REPEATS_REGION domain-containing protein.	0.733
LOC113571395	pclaf	ENSEEEP00000000250	ENSEEEP00000041804	Polymerase (DNA directed), epsilon 2.	PAF domain-containing protein.	0.560