(81 nodes) Cortical cytoskeleton network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113586020	Uncharacterized protein. (920 aa)
	LOC113576819	Uncharacterized protein. (1438 aa)
	ENSEEEP00000028378	ADF-H domain-containing protein. (112 aa)
	cttn	Cortactin. (556 aa)
	anln	PH domain-containing protein. (1166 aa)
	LOC113587491	Protein phosphatase 1, regulatory subunit 9Bb. (779 aa)
	shroom2	Shroom family member 2a. (449 aa)
	ENSEEEP00000031992	PDZ domain-containing protein. (84 aa)
	LOC113585178	Actinin alpha 3b. (931 aa)
	ENSEEEP00000033787	Uncharacterized protein. (429 aa)
	LOC113579076	Uncharacterized protein. (296 aa)
	LOC113589928	Actinin, alpha 4. (896 aa)
	ENSEEEP00000037539	Zgc:77748. (293 aa)
	LOC113575175	Uncharacterized protein. (288 aa)
	LOC113567648	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (477 aa)
	ENSEEEP00000038881	Melanophilin a. (577 aa)
	LOC113580296	Regulating synaptic membrane exocytosis 1a. (1376 aa)
	LOC113588393	Protein phosphatase 1 regulatory subunit 9A-like A. (1366 aa)
	dbn1	Drebrin 1. (540 aa)
	sptan1	Spectrin alpha, non-erythrocytic 1. (2481 aa)
	LOC113583290	Shroom family member 1. (1378 aa)
	ENSEEEP00000044830	Drebrin-like a. (424 aa)
	LOC113586436	ELKS/RAB6-interacting/CAST family member 1a. (990 aa)
	LOC113574145	Spectrin beta chain; Belongs to the spectrin family. (2436 aa)
	ENSEEEP00000046463	Caldesmon 1b. (506 aa)
	ppp1r9a	Protein phosphatase 1, regulatory subunit 9A. (1032 aa)
	pjvk	Pejvakin. (346 aa)
	LOC113581253	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (441 aa)
	ENSEEEP00000049699	ASD2 domain-containing protein. (134 aa)
	shroom4	Uncharacterized protein. (1415 aa)
	LOC113582049	Uncharacterized protein. (1131 aa)
	LOC113576381	Uncharacterized protein. (258 aa)
	LOC113569665	Hematopoietic cell-specific Lyn substrate 1. (484 aa)
	golgb1	Golgin B1. (2814 aa)
	Sptbn4	Uncharacterized protein. (562 aa)
	Kncn	Kinocilin. (117 aa)
	sptbn1	Spectrin beta chain; Belongs to the spectrin family. (2309 aa)
	dbnl	Uncharacterized protein. (474 aa)
	rims3	Regulating synaptic membrane exocytosis 3. (323 aa)
	cotl1	ADF-H domain-containing protein. (142 aa)
	plekhh2	Pleckstrin homology domain containing, family H (with MyTH4 domain) member 2. (1387 aa)
	cldn5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	nf2	FERM domain-containing protein. (641 aa)
	LOC113591262	Vinculin b. (1104 aa)
	ENSEEEP00000018442	Uncharacterized protein. (296 aa)
	WDR1	WD repeat domain 1. (608 aa)
	LOC113567972	Uncharacterized protein. (550 aa)
	myrip	Myosin VIIA and Rab interacting protein. (844 aa)
	LOC113591548	Uncharacterized protein. (757 aa)
	ENSEEEP00000014593	Uncharacterized protein. (635 aa)
	ENSEEEP00000014449	Zf-piccolo domain-containing protein. (461 aa)
	ENSEEEP00000014445	Uncharacterized protein. (1157 aa)
	ERC2	ELKS/RAB6-interacting/CAST family member 2. (897 aa)
	LOC113580502	PH domain-containing protein. (889 aa)
	llgl2	LLGL domain-containing protein. (1021 aa)
	LOC113574049	FERM domain-containing protein. (587 aa)
	LLGL1	LLGL scribble cell polarity complex component 1. (1041 aa)
	LOC113586602	Protein phosphatase 1 regulatory subunit 9A-like B. (1246 aa)
	LOC113583915	ELKS/RAB6-interacting/CAST family member 1. (1048 aa)
	LOC113574674	Uncharacterized protein. (960 aa)
	ENSEEEP00000008394	PDZ domain-containing protein. (303 aa)
	LOC113580486	Si:dkey-40c11.2. (716 aa)
	shroom3	Shroom family member 3. (1742 aa)
	ppp1r9b	Protein phosphatase 1, regulatory subunit 9Ba. (857 aa)
	ENSEEEP00000007043	PDZ domain-containing protein. (94 aa)
	ENSEEEP00000007040	ASD2 domain-containing protein. (416 aa)
	LOC113578866	Spectrin beta chain; Belongs to the spectrin family. (2289 aa)
	ENSEEEP00000005269	Bassoon (presynaptic cytomatrix protein) b. (2854 aa)
	LOC113583817	ELKS/RAB6-interacting/CAST family member 2. (968 aa)
	sptbn5	Spectrin, beta, non-erythrocytic 5. (3015 aa)
	ENSEEEP00000004677	Uncharacterized protein. (561 aa)
	LOC113583225	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
	ENSEEEP00000003493	Uncharacterized protein. (454 aa)
	ENSEEEP00000000934	RabBD domain-containing protein. (114 aa)
	LOC113568164	CDK5 regulatory subunit associated protein 2. (1558 aa)
	ENSEEEP00000000274	Regulating synaptic membrane exocytosis 2b. (297 aa)
	ENSEEEP00000000211	PDZ domain-containing protein. (417 aa)
	LOC113590412	Uncharacterized protein. (353 aa)
	SPTBN4	Spectrin beta, non-erythrocytic 4. (1183 aa)
	LOC113584158	Uncharacterized protein. (293 aa)
	LOC113580116	Si:ch211-220f16.2. (1860 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000000211	ENSEEEP00000000274	ENSEEEP00000000211	ENSEEEP00000000274	PDZ domain-containing protein.	Regulating synaptic membrane exocytosis 2b.	0.817
ENSEEEP00000000211	ERC2	ENSEEEP00000000211	ENSEEEP00000014280	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 2.	0.780
ENSEEEP00000000211	LOC113583817	ENSEEEP00000000211	ENSEEEP00000005262	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 2.	0.780
ENSEEEP00000000211	LOC113583915	ENSEEEP00000000211	ENSEEEP00000010385	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 1.	0.780
ENSEEEP00000000211	LOC113586436	ENSEEEP00000000211	ENSEEEP00000046006	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 1a.	0.780
ENSEEEP00000000274	ENSEEEP00000000211	ENSEEEP00000000274	ENSEEEP00000000211	Regulating synaptic membrane exocytosis 2b.	PDZ domain-containing protein.	0.817
ENSEEEP00000004677	LOC113567972	ENSEEEP00000004677	ENSEEEP00000016843	Uncharacterized protein.	Uncharacterized protein.	0.451
ENSEEEP00000004677	LOC113591548	ENSEEEP00000004677	ENSEEEP00000015089	Uncharacterized protein.	Uncharacterized protein.	0.591
ENSEEEP00000004677	Sptbn4	ENSEEEP00000004677	ENSEEEP00000027021	Uncharacterized protein.	Uncharacterized protein.	0.531
ENSEEEP00000004677	sptan1	ENSEEEP00000004677	ENSEEEP00000044089	Uncharacterized protein.	Spectrin alpha, non-erythrocytic 1.	0.852
ENSEEEP00000008394	ERC2	ENSEEEP00000008394	ENSEEEP00000014280	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 2.	0.780
ENSEEEP00000008394	LOC113583817	ENSEEEP00000008394	ENSEEEP00000005262	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 2.	0.780
ENSEEEP00000008394	LOC113583915	ENSEEEP00000008394	ENSEEEP00000010385	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 1.	0.780
ENSEEEP00000008394	LOC113586436	ENSEEEP00000008394	ENSEEEP00000046006	PDZ domain-containing protein.	ELKS/RAB6-interacting/CAST family member 1a.	0.780
ENSEEEP00000014445	ENSEEEP00000014449	ENSEEEP00000014445	ENSEEEP00000014449	Uncharacterized protein.	Zf-piccolo domain-containing protein.	0.898
ENSEEEP00000014449	ENSEEEP00000014445	ENSEEEP00000014449	ENSEEEP00000014445	Zf-piccolo domain-containing protein.	Uncharacterized protein.	0.898
ENSEEEP00000014593	LOC113591548	ENSEEEP00000014593	ENSEEEP00000015089	Uncharacterized protein.	Uncharacterized protein.	0.651
ENSEEEP00000014593	Sptbn4	ENSEEEP00000014593	ENSEEEP00000027021	Uncharacterized protein.	Uncharacterized protein.	0.670
ENSEEEP00000014593	sptan1	ENSEEEP00000014593	ENSEEEP00000044089	Uncharacterized protein.	Spectrin alpha, non-erythrocytic 1.	0.845
ENSEEEP00000033787	LOC113582049	ENSEEEP00000033787	ENSEEEP00000050538	Uncharacterized protein.	Uncharacterized protein.	0.565