(45 nodes) Microtubule polymerization or depolymerization network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	katnb1	Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (691 aa)
	LOC113582054	Uncharacterized protein. (263 aa)
	CLASP1	Cytoplasmic linker associated protein 1. (1475 aa)
	LOC113573266	Zgc:171844. (176 aa)
	LOC113574368	Zinc finger protein 207, a. (403 aa)
	mzt1	Uncharacterized protein. (75 aa)
	tubg1	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (449 aa)
	bmerb1	BMERB domain-containing protein. (199 aa)
	LOC113578832	Uncharacterized protein. (426 aa)
	LOC113572170	Stathmin; Belongs to the stathmin family. (153 aa)
	LOC113568418	Uncharacterized protein. (670 aa)
	LOC113568634	Uncharacterized protein. (1190 aa)
	ENSEEEP00000020522	Uncharacterized protein. (631 aa)
	ssna1	Uncharacterized protein. (115 aa)
	TPPP	Uncharacterized protein. (229 aa)
	ENSEEEP00000022245	Uncharacterized protein. (552 aa)
	clasp1	Cytoplasmic linker associated protein 1a. (1520 aa)
	LOC113570664	Stathmin 2a. (224 aa)
	LOC113571126	Stathmin; Belongs to the stathmin family. (189 aa)
	ENSEEEP00000028716	Uncharacterized protein. (65 aa)
	LOC113577239	Uncharacterized protein. (207 aa)
	stmn2	Stathmin; Belongs to the stathmin family. (190 aa)
	nde1	NUDE_C domain-containing protein. (327 aa)
	tubgcp2	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (916 aa)
	clasp2	Cytoplasmic linker associated protein 2. (1289 aa)
	kif19	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (946 aa)
	ENSEEEP00000033876	Uncharacterized protein. (215 aa)
	ckap5	Cytoskeleton associated protein 5. (2014 aa)
	kif18a	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (899 aa)
	tubgcp4	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (683 aa)
	LOC113589133	Uncharacterized protein. (181 aa)
	tubgcp5	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1022 aa)
	tubgcp6	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (1682 aa)
	HDGFL3	PWWP domain-containing protein. (207 aa)
	ndel1	NUDE_C domain-containing protein. (342 aa)
	ENSEEEP00000041256	NCK-associated protein 5-like. (1282 aa)
	LOC113572820	NUDE_C domain-containing protein. (350 aa)
	ENSEEEP00000043724	SLAIN motif family, member 2. (490 aa)
	ENSEEEP00000043725	Uncharacterized protein. (114 aa)
	LOC113584785	BMERB domain-containing protein. (180 aa)
	tppp3	Uncharacterized protein. (177 aa)
	nedd1	Neural precursor cell expressed, developmentally down-regulated 1. (661 aa)
	LOC113574184	Uncharacterized protein. (615 aa)
	tubgcp3	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (883 aa)
	ENSEEEP00000049829	Uncharacterized protein. (1217 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000020522	nedd1	ENSEEEP00000020522	ENSEEEP00000045685	Uncharacterized protein.	Neural precursor cell expressed, developmentally down-regulated 1.	0.630
ENSEEEP00000020522	tubg1	ENSEEEP00000020522	ENSEEEP00000010513	Uncharacterized protein.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.443
ENSEEEP00000043724	LOC113568418	ENSEEEP00000043724	ENSEEEP00000014347	SLAIN motif family, member 2.	Uncharacterized protein.	0.684
ENSEEEP00000043724	LOC113568634	ENSEEEP00000043724	ENSEEEP00000019638	SLAIN motif family, member 2.	Uncharacterized protein.	0.684
ENSEEEP00000043724	ckap5	ENSEEEP00000043724	ENSEEEP00000034691	SLAIN motif family, member 2.	Cytoskeleton associated protein 5.	0.684
ENSEEEP00000043725	LOC113568418	ENSEEEP00000043725	ENSEEEP00000014347	Uncharacterized protein.	Uncharacterized protein.	0.684
ENSEEEP00000043725	LOC113568634	ENSEEEP00000043725	ENSEEEP00000019638	Uncharacterized protein.	Uncharacterized protein.	0.684
ENSEEEP00000043725	ckap5	ENSEEEP00000043725	ENSEEEP00000034691	Uncharacterized protein.	Cytoskeleton associated protein 5.	0.684
LOC113568418	ENSEEEP00000043724	ENSEEEP00000014347	ENSEEEP00000043724	Uncharacterized protein.	SLAIN motif family, member 2.	0.684
LOC113568418	ENSEEEP00000043725	ENSEEEP00000014347	ENSEEEP00000043725	Uncharacterized protein.	Uncharacterized protein.	0.684
LOC113568418	LOC113568634	ENSEEEP00000014347	ENSEEEP00000019638	Uncharacterized protein.	Uncharacterized protein.	0.926
LOC113568418	kif18a	ENSEEEP00000014347	ENSEEEP00000036663	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.692
LOC113568418	kif19	ENSEEEP00000014347	ENSEEEP00000033470	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.419
LOC113568418	tubg1	ENSEEEP00000014347	ENSEEEP00000010513	Uncharacterized protein.	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.	0.460
LOC113568418	tubgcp2	ENSEEEP00000014347	ENSEEEP00000032090	Uncharacterized protein.	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.	0.565
LOC113568418	tubgcp3	ENSEEEP00000014347	ENSEEEP00000048905	Uncharacterized protein.	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.	0.423
LOC113568634	ENSEEEP00000043724	ENSEEEP00000019638	ENSEEEP00000043724	Uncharacterized protein.	SLAIN motif family, member 2.	0.684
LOC113568634	ENSEEEP00000043725	ENSEEEP00000019638	ENSEEEP00000043725	Uncharacterized protein.	Uncharacterized protein.	0.684
LOC113568634	LOC113568418	ENSEEEP00000019638	ENSEEEP00000014347	Uncharacterized protein.	Uncharacterized protein.	0.926
LOC113568634	kif18a	ENSEEEP00000019638	ENSEEEP00000036663	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.692