STRINGSTRING
chd1 chd1 ddx1 ddx1 aire aire chd7 chd7 LOC113591245 LOC113591245 ENSEEEP00000016716 ENSEEEP00000016716 mcm5 mcm5 mcm9 mcm9 LOC113574796 LOC113574796 rad50 rad50 LOC113572601 LOC113572601 LOC113577105 LOC113577105 twnk twnk ercc6l ercc6l recql4 recql4 mcm3 mcm3 chd1l chd1l nbn nbn rfc2 rfc2 dhx9 dhx9 rtel1 rtel1 DNA2 DNA2 supv3l1 supv3l1 ENSEEEP00000007003 ENSEEEP00000007003 LOC113569058 LOC113569058 rad51 rad51 ruvbl1 ruvbl1 atrx atrx ascc3 ascc3 pot1 pot1 mcm8 mcm8 MCMDC2 MCMDC2 rfc5 rfc5 chtf8 chtf8 cdc45 cdc45 mcm4 mcm4 ercc3 ercc3 rfc3 rfc3 xrcc6 xrcc6 pif1 pif1 dhx36 dhx36 gins4 gins4 LOC113586799 LOC113586799 gtf2f2 gtf2f2 ENSEEEP00000004858 ENSEEEP00000004858 ENSEEEP00000004846 ENSEEEP00000004846 ENSEEEP00000004841 ENSEEEP00000004841 LOC113579833 LOC113579833 chd9 chd9 rfc4 rfc4 LOC113584344 LOC113584344 brip1 brip1 rpa1 rpa1 LOC113585995 LOC113585995 wrnip1 wrnip1 xrcc5 xrcc5 hfm1 hfm1 ighmbp2 ighmbp2 mcm6 mcm6 LOC113581984 LOC113581984 ruvbl2 ruvbl2 mcm2 mcm2 ercc2 ercc2 gins3 gins3 recql recql helq helq ENSEEEP00000032736 ENSEEEP00000032736 ddx11 ddx11 chtf18 chtf18 blm blm LOC113591872 LOC113591872 gins2 gins2 LOC113575160 LOC113575160 ENSEEEP00000036636 ENSEEEP00000036636 chd2 chd2 helb helb Recql5 Recql5 ENSEEEP00000037634 ENSEEEP00000037634 ENSEEEP00000037636 ENSEEEP00000037636 fbh1 fbh1 LOC113589205 LOC113589205 mcm7 mcm7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chd1Uncharacterized protein. (1731 aa)
ddx1Uncharacterized protein. (740 aa)
aireAutoimmune regulator. (457 aa)
chd7Chromodomain helicase DNA binding protein 7. (2118 aa)
LOC113591245Uncharacterized protein. (743 aa)
ENSEEEP00000016716Helicase ATP-binding domain-containing protein. (320 aa)
mcm5DNA helicase; Belongs to the MCM family. (738 aa)
mcm9MCM domain-containing protein; Belongs to the MCM family. (1143 aa)
LOC113574796Uncharacterized protein. (1895 aa)
rad50RAD50 homolog, double strand break repair protein. (1181 aa)
LOC113572601Uncharacterized protein. (1955 aa)
LOC113577105General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (253 aa)
twnkSF4 helicase domain-containing protein. (135 aa)
ercc6lUncharacterized protein. (1465 aa)
recql4RecQ helicase-like 4. (817 aa)
mcm3DNA helicase; Belongs to the MCM family. (815 aa)
chd1lUncharacterized protein. (1021 aa)
nbnNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (816 aa)
rfc2AAA domain-containing protein. (369 aa)
dhx9Uncharacterized protein. (1220 aa)
rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1163 aa)
DNA2DNA replication helicase/nuclease 2. (1002 aa)
supv3l1Uncharacterized protein. (767 aa)
ENSEEEP00000007003AAA_23 domain-containing protein. (53 aa)
LOC113569058AAA_23 domain-containing protein. (469 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
atrxUncharacterized protein. (1986 aa)
ascc3Uncharacterized protein. (2209 aa)
pot1Protection of telomeres 1 homolog. (767 aa)
mcm8MCM domain-containing protein; Belongs to the MCM family. (844 aa)
MCMDC2Minichromosome maintenance domain containing 2. (372 aa)
rfc5AAA domain-containing protein. (363 aa)
chtf8Uncharacterized protein. (124 aa)
cdc45Uncharacterized protein. (574 aa)
mcm4DNA helicase; Belongs to the MCM family. (848 aa)
ercc3Uncharacterized protein. (823 aa)
rfc3AAA domain-containing protein. (356 aa)
xrcc6Uncharacterized protein. (627 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (636 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1001 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa)
LOC113586799Chromodomain helicase DNA binding protein 5. (1840 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (265 aa)
ENSEEEP00000004858Uncharacterized protein. (350 aa)
ENSEEEP00000004846Uncharacterized protein. (103 aa)
ENSEEEP00000004841Uncharacterized protein. (508 aa)
LOC113579833Chromodomain helicase DNA binding protein 3. (1811 aa)
chd9Chromodomain helicase DNA binding protein 9. (2742 aa)
rfc4AAA domain-containing protein. (357 aa)
LOC113584344DNA helicase; Belongs to the MCM family. (820 aa)
brip1Helicase ATP-binding domain-containing protein. (1220 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (624 aa)
LOC113585995DNA helicase; Belongs to the MCM family. (801 aa)
wrnip1AAA domain-containing protein. (525 aa)
xrcc5Ku domain-containing protein. (740 aa)
hfm1HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae). (1040 aa)
ighmbp2Uncharacterized protein. (1008 aa)
mcm6DNA helicase; Belongs to the MCM family. (830 aa)
LOC113581984DEAH (Asp-Glu-Ala-His) box polypeptide 32a. (742 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (491 aa)
mcm2DNA helicase; Belongs to the MCM family. (908 aa)
ercc2Helicase ATP-binding domain-containing protein. (760 aa)
gins3Sld5 domain-containing protein. (211 aa)
recqlATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (826 aa)
helqUncharacterized protein. (1026 aa)
ENSEEEP00000032736Helicase ATP-binding domain-containing protein. (88 aa)
ddx11DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (622 aa)
chtf18AAA domain-containing protein. (936 aa)
blmBLM RecQ like helicase. (1281 aa)
LOC113591872DEAQ box RNA-dependent ATPase 1. (695 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (182 aa)
LOC113575160Uncharacterized protein. (757 aa)
ENSEEEP00000036636DEAH (Asp-Glu-Ala-His) box polypeptide 32b. (642 aa)
chd2Chromodomain helicase DNA binding protein 2. (1778 aa)
helbHelicase (DNA) B. (1009 aa)
Recql5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (970 aa)
ENSEEEP00000037634ERCC4 domain-containing protein. (1166 aa)
ENSEEEP00000037636Helicase C-terminal domain-containing protein. (432 aa)
fbh1F-box domain-containing protein. (1043 aa)
LOC113589205Chromodomain helicase DNA binding protein 8. (1683 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (732 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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