(36 nodes) Positive regulation of peptidyl-serine phosphorylation network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mad2l2	HORMA domain-containing protein. (215 aa)
	ENSEEEP00000001893	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (221 aa)
	ercc6	Excision repair cross-complementation group 6. (1398 aa)
	bcar3	BCAR3, NSP family adaptor protein. (851 aa)
	TENM1	Teneurin transmembrane protein 1. (2691 aa)
	pink1	Protein kinase domain-containing protein. (579 aa)
	LOC113591061	Teneurin transmembrane protein 1. (2311 aa)
	LOC113590492	Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
	LOC113573801	Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
	LOC113581577	Uncharacterized protein. (355 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1324 aa)
	hax1	HCLS1 associated protein X-1. (286 aa)
	oxt	Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (154 aa)
	LOC113576016	SH2 domain containing 3Ca. (665 aa)
	LOC113587808	NGF domain-containing protein; Belongs to the NGF-beta family. (228 aa)
	gas6	Uncharacterized protein. (649 aa)
	il11	Interleukin 11a. (202 aa)
	LOC113585124	EGF-like domain-containing protein. (616 aa)
	ENSEEEP00000028183	SET and MYND domain containing 3. (427 aa)
	ripk2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (579 aa)
	LOC113589560	Uncharacterized protein. (772 aa)
	LOC113589593	NGF domain-containing protein; Belongs to the NGF-beta family. (198 aa)
	stox1	Stork_head domain-containing protein. (982 aa)
	LOC113586917	Uncharacterized protein. (534 aa)
	ret	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1066 aa)
	LOC113587187	Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (154 aa)
	ENSEEEP00000036375	Uncharacterized protein. (181 aa)
	ENSEEEP00000036876	Sprouty RTK signaling antagonist 2. (281 aa)
	LOC113588667	EGF-like domain-containing protein. (630 aa)
	mapkap1	Uncharacterized protein. (526 aa)
	ENSEEEP00000042140	Urotensin 1. (136 aa)
	RAMP3	Receptor activity modifying protein 3. (176 aa)
	ENSEEEP00000046207	Si:ch211-42i9.8. (833 aa)
	sh2d3c	SH2 domain containing 3Cb. (645 aa)
	fnip1	UDENN FNIP1/2-type domain-containing protein. (1163 aa)
	sfrp2	Uncharacterized protein. (291 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000028183	ercc6	ENSEEEP00000028183	ENSEEEP00000002957	SET and MYND domain containing 3.	Excision repair cross-complementation group 6.	0.494
ENSEEEP00000046207	fnip1	ENSEEEP00000046207	ENSEEEP00000048018	Si:ch211-42i9.8.	UDENN FNIP1/2-type domain-containing protein.	0.643
LOC113573801	LOC113590492	ENSEEEP00000005782	ENSEEEP00000004598	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.902
LOC113585124	LOC113588667	ENSEEEP00000026329	ENSEEEP00000040730	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.901
LOC113586917	LOC113587808	ENSEEEP00000031172	ENSEEEP00000022545	Uncharacterized protein.	NGF domain-containing protein; Belongs to the NGF-beta family.	0.447
LOC113586917	ercc6	ENSEEEP00000031172	ENSEEEP00000002957	Uncharacterized protein.	Excision repair cross-complementation group 6.	0.425
LOC113586917	ripk2	ENSEEEP00000031172	ENSEEEP00000028736	Uncharacterized protein.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.900
LOC113587808	LOC113586917	ENSEEEP00000022545	ENSEEEP00000031172	NGF domain-containing protein; Belongs to the NGF-beta family.	Uncharacterized protein.	0.447
LOC113587808	LOC113589593	ENSEEEP00000022545	ENSEEEP00000030529	NGF domain-containing protein; Belongs to the NGF-beta family.	NGF domain-containing protein; Belongs to the NGF-beta family.	0.901
LOC113587808	ret	ENSEEEP00000022545	ENSEEEP00000035874	NGF domain-containing protein; Belongs to the NGF-beta family.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.483
LOC113587808	ripk2	ENSEEEP00000022545	ENSEEEP00000028736	NGF domain-containing protein; Belongs to the NGF-beta family.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.447
LOC113588667	LOC113585124	ENSEEEP00000040730	ENSEEEP00000026329	EGF-like domain-containing protein.	EGF-like domain-containing protein.	0.901
LOC113589593	LOC113587808	ENSEEEP00000030529	ENSEEEP00000022545	NGF domain-containing protein; Belongs to the NGF-beta family.	NGF domain-containing protein; Belongs to the NGF-beta family.	0.901
LOC113590492	LOC113573801	ENSEEEP00000004598	ENSEEEP00000005782	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.902
ercc6	ENSEEEP00000028183	ENSEEEP00000002957	ENSEEEP00000028183	Excision repair cross-complementation group 6.	SET and MYND domain containing 3.	0.494
ercc6	LOC113586917	ENSEEEP00000002957	ENSEEEP00000031172	Excision repair cross-complementation group 6.	Uncharacterized protein.	0.425
ercc6	mad2l2	ENSEEEP00000002957	ENSEEEP00000001265	Excision repair cross-complementation group 6.	HORMA domain-containing protein.	0.466
ercc6	ripk2	ENSEEEP00000002957	ENSEEEP00000028736	Excision repair cross-complementation group 6.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.531
fnip1	ENSEEEP00000046207	ENSEEEP00000048018	ENSEEEP00000046207	UDENN FNIP1/2-type domain-containing protein.	Si:ch211-42i9.8.	0.643
mad2l2	ercc6	ENSEEEP00000001265	ENSEEEP00000002957	HORMA domain-containing protein.	Excision repair cross-complementation group 6.	0.466