(38 nodes) Homologous recombination network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hdac10	Hist_deacetyl domain-containing protein. (673 aa)
	ENSEEEP00000007003	AAA_23 domain-containing protein. (53 aa)
	rad51d	RECA_2 domain-containing protein. (338 aa)
	psmc3ip	Uncharacterized protein. (237 aa)
	C1orf146	Chromosome 1 open reading frame 146. (169 aa)
	msh4	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (894 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1181 aa)
	spo11	SPO11 meiotic protein covalently bound to DSB. (368 aa)
	mnd1	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (205 aa)
	mlh1	DNA_mis_repair domain-containing protein. (724 aa)
	ENSEEEP00000016716	Helicase ATP-binding domain-containing protein. (320 aa)
	ENSEEEP00000018543	Methionine sulfoxide reductase B1b. (259 aa)
	ENSEEEP00000019307	Uncharacterized protein. (258 aa)
	ercc4	ERCC4 domain-containing protein. (899 aa)
	trip13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (423 aa)
	dmc1	DNA meiotic recombinase 1. (324 aa)
	hsf2bp	Heat shock transcription factor 2 binding protein. (329 aa)
	msh5	MutS homolog 5. (760 aa)
	LOC113575016	Ankyrin repeat domain 31. (219 aa)
	LOC113589524	RECA_2 domain-containing protein. (121 aa)
	ENSEEEP00000029998	Uncharacterized protein. (608 aa)
	ankle1	Zgc:85936. (862 aa)
	cenpx	Uncharacterized protein. (81 aa)
	ENSEEEP00000037634	ERCC4 domain-containing protein. (1166 aa)
	ENSEEEP00000037636	Helicase C-terminal domain-containing protein. (432 aa)
	Ccnb1ip1	Cyclin B1 interacting protein 1. (111 aa)
	mus81	MUS81 structure-specific endonuclease subunit. (615 aa)
	LOC113582703	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1597 aa)
	hfm1	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae). (1040 aa)
	ENSEEEP00000046229	Uncharacterized protein. (283 aa)
	top2b	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1600 aa)
	eme1	Essential meiotic structure-specific endonuclease 1. (550 aa)
	fancd2	FA complementation group D2. (1261 aa)
	rmi1	DUF1767 domain-containing protein. (587 aa)
	LOC113568250	RAD51 paralog C. (260 aa)
	ENSEEEP00000005036	Uncharacterized protein. (813 aa)
	syce3	Uncharacterized protein. (96 aa)
	LOC113569058	AAA_23 domain-containing protein. (469 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1orf146	ENSEEEP00000029998	ENSEEEP00000011980	ENSEEEP00000029998	Chromosome 1 open reading frame 146.	Uncharacterized protein.	0.438
C1orf146	hfm1	ENSEEEP00000011980	ENSEEEP00000044990	Chromosome 1 open reading frame 146.	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae).	0.569
C1orf146	msh4	ENSEEEP00000011980	ENSEEEP00000012710	Chromosome 1 open reading frame 146.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.536
C1orf146	msh5	ENSEEEP00000011980	ENSEEEP00000026629	Chromosome 1 open reading frame 146.	MutS homolog 5.	0.443
Ccnb1ip1	msh4	ENSEEEP00000042089	ENSEEEP00000012710	Cyclin B1 interacting protein 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.403
ENSEEEP00000005036	LOC113575016	ENSEEEP00000005036	ENSEEEP00000028600	Uncharacterized protein.	Ankyrin repeat domain 31.	0.470
ENSEEEP00000005036	spo11	ENSEEEP00000005036	ENSEEEP00000014255	Uncharacterized protein.	SPO11 meiotic protein covalently bound to DSB.	0.559
ENSEEEP00000007003	ENSEEEP00000016716	ENSEEEP00000007003	ENSEEEP00000016716	AAA_23 domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.453
ENSEEEP00000007003	ENSEEEP00000018543	ENSEEEP00000007003	ENSEEEP00000018543	AAA_23 domain-containing protein.	Methionine sulfoxide reductase B1b.	0.685
ENSEEEP00000007003	ENSEEEP00000019307	ENSEEEP00000007003	ENSEEEP00000019307	AAA_23 domain-containing protein.	Uncharacterized protein.	0.480
ENSEEEP00000007003	ENSEEEP00000037634	ENSEEEP00000007003	ENSEEEP00000037634	AAA_23 domain-containing protein.	ERCC4 domain-containing protein.	0.453
ENSEEEP00000007003	ENSEEEP00000037636	ENSEEEP00000007003	ENSEEEP00000037636	AAA_23 domain-containing protein.	Helicase C-terminal domain-containing protein.	0.453
ENSEEEP00000007003	LOC113568250	ENSEEEP00000007003	ENSEEEP00000004244	AAA_23 domain-containing protein.	RAD51 paralog C.	0.671
ENSEEEP00000007003	LOC113589524	ENSEEEP00000007003	ENSEEEP00000028964	AAA_23 domain-containing protein.	RECA_2 domain-containing protein.	0.671
ENSEEEP00000007003	dmc1	ENSEEEP00000007003	ENSEEEP00000021955	AAA_23 domain-containing protein.	DNA meiotic recombinase 1.	0.645
ENSEEEP00000007003	eme1	ENSEEEP00000007003	ENSEEEP00000051609	AAA_23 domain-containing protein.	Essential meiotic structure-specific endonuclease 1.	0.506
ENSEEEP00000007003	ercc4	ENSEEEP00000007003	ENSEEEP00000020903	AAA_23 domain-containing protein.	ERCC4 domain-containing protein.	0.470
ENSEEEP00000007003	mus81	ENSEEEP00000007003	ENSEEEP00000042552	AAA_23 domain-containing protein.	MUS81 structure-specific endonuclease subunit.	0.637
ENSEEEP00000007003	rad51d	ENSEEEP00000007003	ENSEEEP00000008581	AAA_23 domain-containing protein.	RECA_2 domain-containing protein.	0.751
ENSEEEP00000007003	rmi1	ENSEEEP00000007003	ENSEEEP00000003636	AAA_23 domain-containing protein.	DUF1767 domain-containing protein.	0.658