STRINGSTRING
LOC113589623 LOC113589623 ercc2 ercc2 aatf aatf LOC113592334 LOC113592334 cul3 cul3 ENSEEEP00000025333 ENSEEEP00000025333 sass6 sass6 top1 top1 LOC113567833 LOC113567833
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC113589623TOPEUc domain-containing protein. (296 aa)
ercc2Helicase ATP-binding domain-containing protein. (760 aa)
aatfUncharacterized protein. (550 aa)
LOC113592334CULLIN_2 domain-containing protein; Belongs to the cullin family. (560 aa)
cul3Cullin 3; Belongs to the cullin family. (734 aa)
ENSEEEP00000025333Topoisom_I_N domain-containing protein. (150 aa)
sass6Uncharacterized protein. (647 aa)
top1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (725 aa)
LOC113567833CULLIN_2 domain-containing protein; Belongs to the cullin family. (232 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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