(25 nodes) Main axon network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nav1	Neuron navigator 1b. (1840 aa)
	crhbp	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (321 aa)
	LOC113582016	Uncharacterized protein. (415 aa)
	c9orf72	Uncharacterized protein. (498 aa)
	ENSEEEP00000042140	Urotensin 1. (136 aa)
	LOC113579711	Amino acid transporter. (539 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (385 aa)
	cntn2	Contactin 2. (1038 aa)
	hapln2	Hyaluronan and proteoglycan link protein 2. (339 aa)
	ENSEEEP00000029400	Uncharacterized protein. (130 aa)
	kcnab2	Aldo_ket_red domain-containing protein. (397 aa)
	LOC113574409	Ig-like domain-containing protein. (209 aa)
	slc1a2	Amino acid transporter. (549 aa)
	cldn5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
	ENSEEEP00000021979	Uncharacterized protein. (127 aa)
	dag1	Peptidase S72 domain-containing protein. (861 aa)
	LOC113591642	Par-3 family cell polarity regulator alpha, b. (1296 aa)
	LOC113568532	Uncharacterized protein. (273 aa)
	ENSEEEP00000015777	Potassium voltage-gated channel, shaker-related subfamily, beta member 2 b. (447 aa)
	LOC113578874	Peptidase S72 domain-containing protein. (845 aa)
	ENSEEEP00000013001	Potassium voltage-gated channel, shaker-related subfamily, beta member 1 b. (274 aa)
	LOC113579404	Uncharacterized protein. (1307 aa)
	LOC113586031	Sodium channel, voltage-gated, type I, beta b. (229 aa)
	LOC113583225	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
	dagla	Diacylglycerol lipase, alpha. (1077 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000042140	crhbp	ENSEEEP00000042140	ENSEEEP00000052535	Urotensin 1.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.860
LOC113574409	LOC113586031	ENSEEEP00000023808	ENSEEEP00000007219	Ig-like domain-containing protein.	Sodium channel, voltage-gated, type I, beta b.	0.905
LOC113578874	dag1	ENSEEEP00000014542	ENSEEEP00000020941	Peptidase S72 domain-containing protein.	Peptidase S72 domain-containing protein.	0.902
LOC113579404	LOC113583225	ENSEEEP00000011193	ENSEEEP00000004104	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
LOC113579404	LOC113591642	ENSEEEP00000011193	ENSEEEP00000020322	Uncharacterized protein.	Par-3 family cell polarity regulator alpha, b.	0.902
LOC113579404	cldn5	ENSEEEP00000011193	ENSEEEP00000022020	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
LOC113583225	LOC113579404	ENSEEEP00000004104	ENSEEEP00000011193	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.650
LOC113583225	LOC113591642	ENSEEEP00000004104	ENSEEEP00000020322	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Par-3 family cell polarity regulator alpha, b.	0.650
LOC113583225	cldn5	ENSEEEP00000004104	ENSEEEP00000022020	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.654
LOC113586031	LOC113574409	ENSEEEP00000007219	ENSEEEP00000023808	Sodium channel, voltage-gated, type I, beta b.	Ig-like domain-containing protein.	0.905
LOC113591642	LOC113579404	ENSEEEP00000020322	ENSEEEP00000011193	Par-3 family cell polarity regulator alpha, b.	Uncharacterized protein.	0.902
LOC113591642	LOC113583225	ENSEEEP00000020322	ENSEEEP00000004104	Par-3 family cell polarity regulator alpha, b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
LOC113591642	cldn5	ENSEEEP00000020322	ENSEEEP00000022020	Par-3 family cell polarity regulator alpha, b.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.650
cldn5	LOC113579404	ENSEEEP00000022020	ENSEEEP00000011193	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.650
cldn5	LOC113583225	ENSEEEP00000022020	ENSEEEP00000004104	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.654
cldn5	LOC113591642	ENSEEEP00000022020	ENSEEEP00000020322	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Par-3 family cell polarity regulator alpha, b.	0.650
crhbp	ENSEEEP00000042140	ENSEEEP00000052535	ENSEEEP00000042140	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	Urotensin 1.	0.860
dag1	LOC113578874	ENSEEEP00000020941	ENSEEEP00000014542	Peptidase S72 domain-containing protein.	Peptidase S72 domain-containing protein.	0.902