(68 nodes) Maintenance of protein location network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSEEEP00000051360	Cdkn1a interacting zinc finger protein 1b. (346 aa)
	LOC113578105	Twinfilin actin-binding protein 1b. (341 aa)
	LOC113584842	RAN GTPase activating protein 1a. (551 aa)
	ENSEEEP00000051616	Polycystic kidney disease 1b. (3060 aa)
	vps13a	Vacuolar protein sorting 13 homolog A (S. cerevisiae). (3207 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (294 aa)
	rer1	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment. (196 aa)
	faf1	Fas (TNFRSF6) associated factor 1. (664 aa)
	pink1	Protein kinase domain-containing protein. (579 aa)
	LOC113589334	Uncharacterized protein. (759 aa)
	LOC113568244	Twinfilin actin-binding protein 2b. (329 aa)
	LOC113587186	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
	LOC113569195	CW-type domain-containing protein. (900 aa)
	ankrd13c	ANK_REP_REGION domain-containing protein. (525 aa)
	nrm	Uncharacterized protein. (277 aa)
	pfn4	Profilin; Belongs to the profilin family. (115 aa)
	LOC113573217	ER lumen protein-retaining receptor. (226 aa)
	LOC113570958	Uncharacterized protein. (212 aa)
	LOC113574777	BZIP domain-containing protein. (379 aa)
	supt7l	BTP domain-containing protein. (424 aa)
	gopc	Golgi-associated PDZ and coiled-coil motif containing. (443 aa)
	vps13d	Vacuolar protein sorting 13 homolog D (S. cerevisiae). (4320 aa)
	tapt1	Transmembrane anterior posterior transformation 1b. (562 aa)
	LOC113583425	Immunoglobulin superfamily member 11. (412 aa)
	insig1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (257 aa)
	tspo	Uncharacterized protein. (161 aa)
	LOC113571703	ANK_REP_REGION domain-containing protein. (308 aa)
	ENSEEEP00000021776	Si:dkey-92f12.2. (520 aa)
	LOC113574869	RanGAP1_C domain-containing protein. (562 aa)
	LOC113590308	Uncharacterized protein. (740 aa)
	LOC113570626	Uncharacterized protein. (470 aa)
	LOC113581705	Uncharacterized protein. (192 aa)
	LOC113588867	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (323 aa)
	ENSEEEP00000029377	PLAT domain-containing protein. (205 aa)
	arl2bp	ARL2_Bind_BART domain-containing protein. (198 aa)
	scin	Scinderin. (773 aa)
	LOC113584622	SUN domain-containing protein. (893 aa)
	taf3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (774 aa)
	LOC113570774	Transmembrane anterior posterior transformation 1a. (545 aa)
	kdelr3	ER lumen protein-retaining receptor. (215 aa)
	nrros	Uncharacterized protein. (687 aa)
	hspa5	Uncharacterized protein; Belongs to the heat shock protein 70 family. (665 aa)
	sorl1	Sortilin-related receptor, L(DLR class) A repeats containing. (2213 aa)
	psmd10	ANK_REP_REGION domain-containing protein. (233 aa)
	sufu	Suppressor of fused homolog. (485 aa)
	vps13c	Vacuolar protein sorting 13 homolog C (S. cerevisiae). (3643 aa)
	LOC113586950	Cdkn1a interacting zinc finger protein 1a. (636 aa)
	ENSEEEP00000036804	Uncharacterized protein. (151 aa)
	LOC113589132	ANK_REP_REGION domain-containing protein. (411 aa)
	ENSEEEP00000037529	Bardet-Biedl syndrome 4. (356 aa)
	sun1	SUN domain-containing protein. (1008 aa)
	LOC113590739	Uncharacterized protein. (51 aa)
	LOC113571291	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (50 aa)
	ENSEEEP00000039644	CTCK domain-containing protein. (202 aa)
	ENSEEEP00000040955	Uncharacterized protein. (143 aa)
	insig2	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (227 aa)
	LOC113590359	Un-named hu7912. (1031 aa)
	LOC113574009	Uncharacterized protein. (237 aa)
	LOC113571875	Uncharacterized protein. (384 aa)
	LOC113590388	Uncharacterized protein. (293 aa)
	LOC113588456	BZIP domain-containing protein. (500 aa)
	golph3	Uncharacterized protein. (293 aa)
	bard1	BRCA1 associated RING domain 1. (689 aa)
	arl2	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	LOC113577500	MORC family CW-type zinc finger 3b. (530 aa)
	ENSEEEP00000050367	Uncharacterized protein. (247 aa)
	ENSEEEP00000050369	Morc6_S5 domain-containing protein. (298 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000021776	LOC113584622	ENSEEEP00000021776	ENSEEEP00000032050	Si:dkey-92f12.2.	SUN domain-containing protein.	0.429
ENSEEEP00000021776	sun1	ENSEEEP00000021776	ENSEEEP00000037574	Si:dkey-92f12.2.	SUN domain-containing protein.	0.408
LOC113568244	pfn4	ENSEEEP00000004219	ENSEEEP00000008680	Twinfilin actin-binding protein 2b.	Profilin; Belongs to the profilin family.	0.483
LOC113570958	rer1	ENSEEEP00000008734	ENSEEEP00000001977	Uncharacterized protein.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.464
LOC113571291	LOC113588867	ENSEEEP00000038189	ENSEEEP00000026828	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.	0.902
LOC113571703	LOC113589132	ENSEEEP00000020925	ENSEEEP00000037325	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.877
LOC113571875	pfn4	ENSEEEP00000041893	ENSEEEP00000008680	Uncharacterized protein.	Profilin; Belongs to the profilin family.	0.483
LOC113573217	rer1	ENSEEEP00000008720	ENSEEEP00000001977	ER lumen protein-retaining receptor.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.464
LOC113578105	pfn4	ENSEEEP00000051483	ENSEEEP00000008680	Twinfilin actin-binding protein 1b.	Profilin; Belongs to the profilin family.	0.483
LOC113584622	ENSEEEP00000021776	ENSEEEP00000032050	ENSEEEP00000021776	SUN domain-containing protein.	Si:dkey-92f12.2.	0.429
LOC113588867	LOC113571291	ENSEEEP00000026828	ENSEEEP00000038189	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.	0.902
LOC113589132	LOC113571703	ENSEEEP00000037325	ENSEEEP00000020925	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.877
LOC113589132	nfkbia	ENSEEEP00000037325	ENSEEEP00000027612	ANK_REP_REGION domain-containing protein.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.	0.878
LOC113589132	psmd10	ENSEEEP00000037325	ENSEEEP00000035198	ANK_REP_REGION domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.417
LOC113589334	pfn4	ENSEEEP00000004169	ENSEEEP00000008680	Uncharacterized protein.	Profilin; Belongs to the profilin family.	0.405
LOC113590308	pfn4	ENSEEEP00000024878	ENSEEEP00000008680	Uncharacterized protein.	Profilin; Belongs to the profilin family.	0.405
arl2	arl2bp	ENSEEEP00000049631	ENSEEEP00000030830	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	ARL2_Bind_BART domain-containing protein.	0.979
arl2bp	arl2	ENSEEEP00000030830	ENSEEEP00000049631	ARL2_Bind_BART domain-containing protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.979
cdk5	pink1	ENSEEEP00000001551	ENSEEEP00000003966	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.406
kdelr3	rer1	ENSEEEP00000032818	ENSEEEP00000001977	ER lumen protein-retaining receptor.	Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.	0.464