(44 nodes) Establishment or maintenance of epithelial cell apical/basal polarity network (Electrophorus electricus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113569932	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (221 aa)
	LOC113572585	Uncharacterized protein. (191 aa)
	ENSEEEP00000005529	Par3_HAL_N_term domain-containing protein. (62 aa)
	ENSEEEP00000005534	PDZ domain-containing protein. (167 aa)
	Pard3b	Uncharacterized protein. (115 aa)
	ENSEEEP00000005551	Par-3 family cell polarity regulator beta a. (830 aa)
	ENSEEEP00000006807	Uncharacterized protein. (143 aa)
	mpp5	Uncharacterized protein; Belongs to the MAGUK family. (708 aa)
	LOC113579404	Uncharacterized protein. (1307 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (721 aa)
	dlg5	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1950 aa)
	LOC113586656	Uncharacterized protein. (191 aa)
	LOC113592206	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (953 aa)
	LOC113575458	Uncharacterized protein. (191 aa)
	ENSEEEP00000015178	Cell division cycle 42, like. (187 aa)
	pdcd6ip	BRO1 domain-containing protein. (876 aa)
	ttc8	TPR_REGION domain-containing protein. (515 aa)
	LOC113591642	Par-3 family cell polarity regulator alpha, b. (1296 aa)
	dlg1	Uncharacterized protein; Belongs to the MAGUK family. (908 aa)
	LOC113574831	Uncharacterized protein. (688 aa)
	nt5dc2	Uncharacterized protein. (598 aa)
	ilk	Integrin-linked kinase. (482 aa)
	ENSEEEP00000027194	Ig-like domain-containing protein. (123 aa)
	ENSEEEP00000027195	Ig-like domain-containing protein. (143 aa)
	dlg3	Discs, large homolog 3 (Drosophila); Belongs to the MAGUK family. (859 aa)
	pdzd11	PDZ domain-containing protein. (142 aa)
	crb2	Crumbs family member 2b. (1445 aa)
	dlg2	Discs, large homolog 2 (Drosophila); Belongs to the MAGUK family. (828 aa)
	Dlg2	L27_1 domain-containing protein. (68 aa)
	LOC113579531	Discs, large homolog 1 (Drosophila); Belongs to the MAGUK family. (873 aa)
	prkci	Protein kinase C, iota; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (558 aa)
	ENSEEEP00000035945	EGF-like domain-containing protein. (183 aa)
	LOC113576705	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (208 aa)
	myo9a	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2247 aa)
	LOC113571819	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2443 aa)
	LOC113586450	Uncharacterized protein. (577 aa)
	LOC113588290	Uncharacterized protein. (149 aa)
	LOC113589280	Crumbs family member 1, photoreceptor morphogenesis associated. (1350 aa)
	ENSEEEP00000048242	Microtubule crosslinking factor 1. (569 aa)
	pard6a	Par-6 family cell polarity regulator alpha. (376 aa)
	ptk7	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1064 aa)
	Lin7a	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (230 aa)
	ENSEEEP00000052597	Uncharacterized protein. (311 aa)
	ENSEEEP00000052598	Uncharacterized protein. (154 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC113575458	ENSEEEP00000011237	ENSEEEP00000014086	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.481
CDH2	LOC113586656	ENSEEEP00000011237	ENSEEEP00000012752	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.481
CDH2	LOC113592206	ENSEEEP00000011237	ENSEEEP00000013634	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.900
Dlg2	LOC113569932	ENSEEEP00000031880	ENSEEEP00000002126	L27_1 domain-containing protein.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.426
Dlg2	LOC113576705	ENSEEEP00000031880	ENSEEEP00000036777	L27_1 domain-containing protein.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.426
Dlg2	Lin7a	ENSEEEP00000031880	ENSEEEP00000052173	L27_1 domain-containing protein.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.426
Dlg2	dlg3	ENSEEEP00000031880	ENSEEEP00000030010	L27_1 domain-containing protein.	Discs, large homolog 3 (Drosophila); Belongs to the MAGUK family.	0.858
Dlg2	pard6a	ENSEEEP00000031880	ENSEEEP00000048416	L27_1 domain-containing protein.	Par-6 family cell polarity regulator alpha.	0.403
ENSEEEP00000005529	pard6a	ENSEEEP00000005529	ENSEEEP00000048416	Par3_HAL_N_term domain-containing protein.	Par-6 family cell polarity regulator alpha.	0.730
ENSEEEP00000005529	prkci	ENSEEEP00000005529	ENSEEEP00000034103	Par3_HAL_N_term domain-containing protein.	Protein kinase C, iota; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.755
ENSEEEP00000005534	pard6a	ENSEEEP00000005534	ENSEEEP00000048416	PDZ domain-containing protein.	Par-6 family cell polarity regulator alpha.	0.730
ENSEEEP00000005534	prkci	ENSEEEP00000005534	ENSEEEP00000034103	PDZ domain-containing protein.	Protein kinase C, iota; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.755
ENSEEEP00000005551	pard6a	ENSEEEP00000005551	ENSEEEP00000048416	Par-3 family cell polarity regulator beta a.	Par-6 family cell polarity regulator alpha.	0.730
ENSEEEP00000005551	prkci	ENSEEEP00000005551	ENSEEEP00000034103	Par-3 family cell polarity regulator beta a.	Protein kinase C, iota; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.755
ENSEEEP00000006807	ENSEEEP00000027194	ENSEEEP00000006807	ENSEEEP00000027194	Uncharacterized protein.	Ig-like domain-containing protein.	0.401
ENSEEEP00000006807	ENSEEEP00000052597	ENSEEEP00000006807	ENSEEEP00000052597	Uncharacterized protein.	Uncharacterized protein.	0.830
ENSEEEP00000006807	ptk7	ENSEEEP00000006807	ENSEEEP00000051190	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.401
ENSEEEP00000015178	LOC113571819	ENSEEEP00000015178	ENSEEEP00000042304	Cell division cycle 42, like.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.677
ENSEEEP00000015178	dlg5	ENSEEEP00000015178	ENSEEEP00000012311	Cell division cycle 42, like.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.416
ENSEEEP00000015178	mpp5	ENSEEEP00000015178	ENSEEEP00000007886	Cell division cycle 42, like.	Uncharacterized protein; Belongs to the MAGUK family.	0.499