(26 nodes) Positive regulation of DNA replication network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	faf1	Fas (TNFRSF6) associated factor 1. (664 aa)
	e2f8	E2F transcription factor 8. (870 aa)
	ENSEEEP00000051360	Cdkn1a interacting zinc finger protein 1b. (346 aa)
	LOC113577379	Bromodomain and PHD finger containing, 3b. (1166 aa)
	ssbp1	Uncharacterized protein. (149 aa)
	ENSEEEP00000042140	Urotensin 1. (136 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (679 aa)
	LOC113591405	Mitogen-activated protein kinase kinase 4a; Belongs to the protein kinase superfamily. (412 aa)
	ENSEEEP00000039572	Uncharacterized protein. (915 aa)
	LOC113586950	Cdkn1a interacting zinc finger protein 1a. (636 aa)
	stoml2	PHB domain-containing protein. (362 aa)
	ino80	Uncharacterized protein. (1128 aa)
	cdc7	Protein kinase domain-containing protein. (555 aa)
	LOC113588796	Si:dkey-217d24.6. (896 aa)
	atrx	Uncharacterized protein. (1986 aa)
	LOC113570943	Protein kinase domain-containing protein. (515 aa)
	LOC113592198	Uncharacterized protein. (632 aa)
	egf	Epidermal growth factor. (1052 aa)
	ENSEEEP00000011546	Uncharacterized protein. (890 aa)
	dhx9	Uncharacterized protein. (1220 aa)
	DNA2	DNA replication helicase/nuclease 2. (1002 aa)
	baz1a	Bromodomain adjacent to zinc finger domain, 1A. (1441 aa)
	dbf4	DBF4 zinc finger. (660 aa)
	nrm	Uncharacterized protein. (277 aa)
	ENSEEEP00000000428	Uncharacterized protein. (383 aa)
	LOC113573063	Bromodomain and PHD finger containing, 3a. (1211 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNA2	ENSEEEP00000011546	ENSEEEP00000009013	ENSEEEP00000011546	DNA replication helicase/nuclease 2.	Uncharacterized protein.	0.887
DNA2	cdc7	ENSEEEP00000009013	ENSEEEP00000023593	DNA replication helicase/nuclease 2.	Protein kinase domain-containing protein.	0.442
DNA2	cdt1	ENSEEEP00000009013	ENSEEEP00000041412	DNA replication helicase/nuclease 2.	Chromatin licensing and DNA replication factor 1.	0.558
DNA2	dbf4	ENSEEEP00000009013	ENSEEEP00000007945	DNA replication helicase/nuclease 2.	DBF4 zinc finger.	0.421
DNA2	ssbp1	ENSEEEP00000009013	ENSEEEP00000043165	DNA replication helicase/nuclease 2.	Uncharacterized protein.	0.610
ENSEEEP00000000428	ENSEEEP00000011546	ENSEEEP00000000428	ENSEEEP00000011546	Uncharacterized protein.	Uncharacterized protein.	0.499
ENSEEEP00000000428	LOC113592198	ENSEEEP00000000428	ENSEEEP00000013335	Uncharacterized protein.	Uncharacterized protein.	0.601
ENSEEEP00000011546	DNA2	ENSEEEP00000011546	ENSEEEP00000009013	Uncharacterized protein.	DNA replication helicase/nuclease 2.	0.887
ENSEEEP00000011546	ENSEEEP00000000428	ENSEEEP00000011546	ENSEEEP00000000428	Uncharacterized protein.	Uncharacterized protein.	0.499
ENSEEEP00000011546	LOC113573063	ENSEEEP00000011546	ENSEEEP00000000410	Uncharacterized protein.	Bromodomain and PHD finger containing, 3a.	0.502
ENSEEEP00000011546	LOC113577379	ENSEEEP00000011546	ENSEEEP00000047336	Uncharacterized protein.	Bromodomain and PHD finger containing, 3b.	0.502
ENSEEEP00000011546	LOC113592198	ENSEEEP00000011546	ENSEEEP00000013335	Uncharacterized protein.	Uncharacterized protein.	0.499
ENSEEEP00000011546	cdt1	ENSEEEP00000011546	ENSEEEP00000041412	Uncharacterized protein.	Chromatin licensing and DNA replication factor 1.	0.782
LOC113570943	LOC113591405	ENSEEEP00000014973	ENSEEEP00000040920	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase 4a; Belongs to the protein kinase superfamily.	0.901
LOC113573063	ENSEEEP00000011546	ENSEEEP00000000410	ENSEEEP00000011546	Bromodomain and PHD finger containing, 3a.	Uncharacterized protein.	0.502
LOC113577379	ENSEEEP00000011546	ENSEEEP00000047336	ENSEEEP00000011546	Bromodomain and PHD finger containing, 3b.	Uncharacterized protein.	0.502
LOC113591405	LOC113570943	ENSEEEP00000040920	ENSEEEP00000014973	Mitogen-activated protein kinase kinase 4a; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.901
LOC113592198	ENSEEEP00000000428	ENSEEEP00000013335	ENSEEEP00000000428	Uncharacterized protein.	Uncharacterized protein.	0.601
LOC113592198	ENSEEEP00000011546	ENSEEEP00000013335	ENSEEEP00000011546	Uncharacterized protein.	Uncharacterized protein.	0.499
atrx	baz1a	ENSEEEP00000018627	ENSEEEP00000008382	Uncharacterized protein.	Bromodomain adjacent to zinc finger domain, 1A.	0.461