(26 nodes) Neuromuscular process controlling balance network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113573104	Beta-hexosaminidase. (536 aa)
	LOC113572036	Tyrosine-protein kinase. (584 aa)
	lrrc45	Uncharacterized protein. (676 aa)
	LOC113584421	SH3 and multiple ankyrin repeat domains 3b. (1602 aa)
	tnr	Tenascin R (restrictin, janusin). (1345 aa)
	LOC113583945	Tyrosine-protein kinase. (1088 aa)
	LOC113590573	MFS domain-containing protein. (586 aa)
	pou4f1	POU domain protein. (367 aa)
	LOC113580523	SH3 and multiple ankyrin repeat domains 3a. (1676 aa)
	hexb	Beta-hexosaminidase. (571 aa)
	ush1c	Usher syndrome 1C. (541 aa)
	ENSEEEP00000017591	FERM_f0 domain-containing protein. (124 aa)
	LOC113572686	Otoferlin b. (1650 aa)
	otof	Otoferlin a. (1940 aa)
	pou4f2	POU domain protein. (385 aa)
	ENSEEEP00000021788	PDZ domain-containing protein. (271 aa)
	LOC113585684	Uncharacterized protein. (228 aa)
	cln8	TLC domain-containing protein. (281 aa)
	gm2a	ML domain-containing protein. (244 aa)
	LOC113571162	Uncharacterized protein. (688 aa)
	GPR88	G protein-coupled receptor 88. (244 aa)
	ENSEEEP00000032781	Protein-tyrosine-phosphatase. (2248 aa)
	Igdcc3	Immunoglobulin superfamily, DCC subclass, member 3. (357 aa)
	fer1l6	Fer-1-like family member 6. (1805 aa)
	ENSEEEP00000045279	Uncharacterized protein. (254 aa)
	LOC113578690	Si:ch211-57n23.4. (727 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC113572036	LOC113583945	ENSEEEP00000003266	ENSEEEP00000010702	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.913
LOC113572686	LOC113590573	ENSEEEP00000019223	ENSEEEP00000013942	Otoferlin b.	MFS domain-containing protein.	0.453
LOC113573104	gm2a	ENSEEEP00000003197	ENSEEEP00000030563	Beta-hexosaminidase.	ML domain-containing protein.	0.733
LOC113573104	hexb	ENSEEEP00000003197	ENSEEEP00000014518	Beta-hexosaminidase.	Beta-hexosaminidase.	0.902
LOC113583945	LOC113572036	ENSEEEP00000010702	ENSEEEP00000003266	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.913
LOC113590573	LOC113572686	ENSEEEP00000013942	ENSEEEP00000019223	MFS domain-containing protein.	Otoferlin b.	0.453
LOC113590573	fer1l6	ENSEEEP00000013942	ENSEEEP00000040118	MFS domain-containing protein.	Fer-1-like family member 6.	0.408
LOC113590573	otof	ENSEEEP00000013942	ENSEEEP00000019317	MFS domain-containing protein.	Otoferlin a.	0.453
cln8	gm2a	ENSEEEP00000029464	ENSEEEP00000030563	TLC domain-containing protein.	ML domain-containing protein.	0.442
fer1l6	LOC113590573	ENSEEEP00000040118	ENSEEEP00000013942	Fer-1-like family member 6.	MFS domain-containing protein.	0.408
gm2a	LOC113573104	ENSEEEP00000030563	ENSEEEP00000003197	ML domain-containing protein.	Beta-hexosaminidase.	0.733
gm2a	cln8	ENSEEEP00000030563	ENSEEEP00000029464	ML domain-containing protein.	TLC domain-containing protein.	0.442
gm2a	hexb	ENSEEEP00000030563	ENSEEEP00000014518	ML domain-containing protein.	Beta-hexosaminidase.	0.733
hexb	LOC113573104	ENSEEEP00000014518	ENSEEEP00000003197	Beta-hexosaminidase.	Beta-hexosaminidase.	0.902
hexb	gm2a	ENSEEEP00000014518	ENSEEEP00000030563	Beta-hexosaminidase.	ML domain-containing protein.	0.733
otof	LOC113590573	ENSEEEP00000019317	ENSEEEP00000013942	Otoferlin a.	MFS domain-containing protein.	0.453