(71 nodes) Positive regulation of chemotaxis network (Electrophorus electricus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lgmn	Uncharacterized protein. (438 aa)
	ENSEEEP00000000755	Protein kinase domain-containing protein. (217 aa)
	met	Uncharacterized protein. (1359 aa)
	LOC113589787	SCY domain-containing protein. (116 aa)
	ENSEEEP00000001893	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (221 aa)
	LOC113583379	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (98 aa)
	ENSEEEP00000003422	Pleiotrophin. (167 aa)
	LOC113578756	Colony stimulating factor 1b (macrophage). (287 aa)
	LOC113590492	Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
	ripor3	PL48 domain-containing protein. (980 aa)
	LOC113583801	TGF_BETA_2 domain-containing protein. (390 aa)
	LOC113569070	G_PROTEIN_RECEP_F1_2 domain-containing protein. (187 aa)
	LOC113573801	Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
	ENSEEEP00000007279	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (453 aa)
	vegfd	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (311 aa)
	LOC113574777	BZIP domain-containing protein. (379 aa)
	ENSEEEP00000010665	Secretogranin II (chromogranin C), b. (585 aa)
	LOC113571635	Macrophage stimulating 1 receptor a. (1355 aa)
	ENSEEEP00000012463	Artemin a. (150 aa)
	mst1r	Macrophage stimulating 1 receptor b. (1354 aa)
	ENSEEEP00000015798	Sema domain-containing protein. (733 aa)
	LOC113568526	SCY domain-containing protein. (98 aa)
	LOC113580664	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	LOC113590157	Uncharacterized protein. (195 aa)
	LOC113585586	C-C motif chemokine. (116 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
	LOC113580699	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa)
	ENSEEEP00000019880	Chemokine (C-C motif) receptor 6a; Belongs to the G-protein coupled receptor 1 family. (368 aa)
	LOC113570511	ADAM metallopeptidase domain 17b. (819 aa)
	ptk2b	Protein tyrosine kinase 2 beta, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (956 aa)
	LOC113578974	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (189 aa)
	LOC113578948	Akirin 1. (171 aa)
	oxsr1	Protein kinase domain-containing protein. (519 aa)
	ENSEEEP00000023828	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (452 aa)
	serpine1	SERPIN domain-containing protein; Belongs to the serpin family. (410 aa)
	ENSEEEP00000024949	TGF_BETA_2 domain-containing protein. (133 aa)
	LOC113585737	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (519 aa)
	gas6	Uncharacterized protein. (649 aa)
	mospd2	Uncharacterized protein. (581 aa)
	ptk2	Protein tyrosine kinase 2. (1124 aa)
	IL16	Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (582 aa)
	LOC113575586	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa)
	cxcl14	Uncharacterized protein. (99 aa)
	il34	Uncharacterized protein. (215 aa)
	csf1r	Colony stimulating factor 1 receptor, a. (955 aa)
	ripor2	RHO family interacting cell polarization regulator 2. (1055 aa)
	LOC113575139	Chemokine (C-C motif) ligand 19b. (102 aa)
	LOC113587949	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	ENSEEEP00000033779	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	scg2	Uncharacterized protein. (616 aa)
	ENSEEEP00000034723	Vascular endothelial growth factor Ba; Belongs to the PDGF/VEGF growth factor family. (135 aa)
	ENSEEEP00000035605	Placental growth factor b; Belongs to the PDGF/VEGF growth factor family. (134 aa)
	ENSEEEP00000036466	Uncharacterized protein. (194 aa)
	adam17	Uncharacterized protein. (848 aa)
	ENSEEEP00000037075	Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	LOC113571245	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1087 aa)
	adam10	Uncharacterized protein. (761 aa)
	LOC113583627	Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (194 aa)
	ENSEEEP00000039748	PDGF_2 domain-containing protein. (87 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1011 aa)
	LOC113571849	ADAM metallopeptidase domain 10b. (789 aa)
	LOC113588456	BZIP domain-containing protein. (500 aa)
	ENSEEEP00000043811	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (166 aa)
	ccr7	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (365 aa)
	LOC113582596	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (992 aa)
	ENSEEEP00000049541	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (236 aa)
	vegfc	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (403 aa)
	ENSEEEP00000050097	Serine threonine kinase 39. (286 aa)
	ENSEEEP00000050098	Uncharacterized protein. (90 aa)
	c1qbp	Uncharacterized protein. (280 aa)
	LOC113573003	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (995 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000000755	ENSEEEP00000003422	ENSEEEP00000000755	ENSEEEP00000003422	Protein kinase domain-containing protein.	Pleiotrophin.	0.660
ENSEEEP00000000755	ENSEEEP00000015798	ENSEEEP00000000755	ENSEEEP00000015798	Protein kinase domain-containing protein.	Sema domain-containing protein.	0.896
ENSEEEP00000000755	LOC113571245	ENSEEEP00000000755	ENSEEEP00000038126	Protein kinase domain-containing protein.	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.484
ENSEEEP00000000755	LOC113571635	ENSEEEP00000000755	ENSEEEP00000012441	Protein kinase domain-containing protein.	Macrophage stimulating 1 receptor a.	0.638
ENSEEEP00000000755	LOC113573003	ENSEEEP00000000755	ENSEEEP00000050993	Protein kinase domain-containing protein.	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.484
ENSEEEP00000000755	met	ENSEEEP00000000755	ENSEEEP00000001062	Protein kinase domain-containing protein.	Uncharacterized protein.	0.638
ENSEEEP00000000755	mst1r	ENSEEEP00000000755	ENSEEEP00000012553	Protein kinase domain-containing protein.	Macrophage stimulating 1 receptor b.	0.638
ENSEEEP00000000755	ptk2	ENSEEEP00000000755	ENSEEEP00000027584	Protein kinase domain-containing protein.	Protein tyrosine kinase 2.	0.484
ENSEEEP00000000755	ptk2b	ENSEEEP00000000755	ENSEEEP00000021177	Protein kinase domain-containing protein.	Protein tyrosine kinase 2 beta, a; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.484
ENSEEEP00000003422	ENSEEEP00000000755	ENSEEEP00000003422	ENSEEEP00000000755	Pleiotrophin.	Protein kinase domain-containing protein.	0.660
ENSEEEP00000003422	ENSEEEP00000015798	ENSEEEP00000003422	ENSEEEP00000015798	Pleiotrophin.	Sema domain-containing protein.	0.660
ENSEEEP00000003422	LOC113571635	ENSEEEP00000003422	ENSEEEP00000012441	Pleiotrophin.	Macrophage stimulating 1 receptor a.	0.660
ENSEEEP00000003422	met	ENSEEEP00000003422	ENSEEEP00000001062	Pleiotrophin.	Uncharacterized protein.	0.660
ENSEEEP00000003422	mst1r	ENSEEEP00000003422	ENSEEEP00000012553	Pleiotrophin.	Macrophage stimulating 1 receptor b.	0.660
ENSEEEP00000007279	csf1r	ENSEEEP00000007279	ENSEEEP00000030891	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family.	Colony stimulating factor 1 receptor, a.	0.462
ENSEEEP00000015798	ENSEEEP00000000755	ENSEEEP00000015798	ENSEEEP00000000755	Sema domain-containing protein.	Protein kinase domain-containing protein.	0.896
ENSEEEP00000015798	ENSEEEP00000003422	ENSEEEP00000015798	ENSEEEP00000003422	Sema domain-containing protein.	Pleiotrophin.	0.660
ENSEEEP00000015798	LOC113571245	ENSEEEP00000015798	ENSEEEP00000038126	Sema domain-containing protein.	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.484
ENSEEEP00000015798	LOC113571635	ENSEEEP00000015798	ENSEEEP00000012441	Sema domain-containing protein.	Macrophage stimulating 1 receptor a.	0.638
ENSEEEP00000015798	LOC113573003	ENSEEEP00000015798	ENSEEEP00000050993	Sema domain-containing protein.	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.484