88 items (Electrophorus electricus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	msh3	MutS homolog 3 (E. coli). (1052 aa)
	parpbp	PARP1 binding protein. (561 aa)
	LOC113581119	Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (570 aa)
	DONSON	Uncharacterized protein. (570 aa)
	LOC113570893	Zgc:153896. (439 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (539 aa)
	gmnn	Geminin, DNA replication inhibitor. (208 aa)
	ENSEEEP00000032310	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa)
	atr	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2627 aa)
	Aunip	Uncharacterized protein. (237 aa)
	tnks	Poly [ADP-ribose] polymerase. (1274 aa)
	ENSEEEP00000034928	Uncharacterized protein. (435 aa)
	blm	BLM RecQ like helicase. (1281 aa)
	men1	Uncharacterized protein. (615 aa)
	LOC113584712	Uncharacterized protein. (812 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (939 aa)
	ankle1	Zgc:85936. (862 aa)
	smg6	SMG6 nonsense mediated mRNA decay factor. (1575 aa)
	ZNF830	Zinc finger protein 830. (334 aa)
	helb	Helicase (DNA) B. (1009 aa)
	ENSEEEP00000037429	Uncharacterized protein. (115 aa)
	Recql5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (970 aa)
	fbh1	F-box domain-containing protein. (1043 aa)
	TNKS2	Poly [ADP-ribose] polymerase. (1102 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1011 aa)
	ercc1	Uncharacterized protein. (346 aa)
	exosc10	HRDC domain-containing protein. (887 aa)
	cdt1	Chromatin licensing and DNA replication factor 1. (679 aa)
	tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (305 aa)
	dcp2	Nudix hydrolase domain-containing protein. (398 aa)
	ENSEEEP00000043857	Telomeric repeat binding factor a. (471 aa)
	xrcc5	Ku domain-containing protein. (740 aa)
	smarcal1	Uncharacterized protein; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (884 aa)
	LOC113582707	WAPL cohesin release factor b. (1021 aa)
	LOC113585273	OTU deubiquitinase, ubiquitin aldehyde binding 1a. (312 aa)
	ankrd1	Ankyrin repeat domain 1a (cardiac muscle). (314 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1371 aa)
	LOC113582596	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (992 aa)
	igfbp2	Uncharacterized protein. (284 aa)
	otub1	Ubiquitin thioesterase. (272 aa)
	Rnf169	RING-type domain-containing protein. (106 aa)
	parp3	Poly [ADP-ribose] polymerase. (527 aa)
	zranb3	Zinc finger, RAN-binding domain containing 3. (1057 aa)
	LOC113568720	H15 domain-containing protein. (213 aa)
	ogg1	8-oxoguanine DNA glycosylase. (389 aa)
	rmi2	Uncharacterized protein. (147 aa)
	dffb	DNA fragmentation factor, beta polypeptide (caspase-activated DNase). (333 aa)
	smchd1	Structural maintenance of chromosomes flexible hinge domain containing 1. (1984 aa)
	ercc6	Excision repair cross-complementation group 6. (1398 aa)
	gmnc	Uncharacterized protein. (366 aa)
	LOC113589886	Poly [ADP-ribose] polymerase. (1168 aa)
	LOC113569058	AAA_23 domain-containing protein. (469 aa)
	trip12	Thyroid hormone receptor interactor 12. (2096 aa)
	LOC113586561	H15 domain-containing protein. (200 aa)
	ENSEEEP00000006834	Uncharacterized protein. (110 aa)
	nrm	Uncharacterized protein. (277 aa)
	ENSEEEP00000007003	AAA_23 domain-containing protein. (53 aa)
	ten1	TEN1 CST complex subunit. (140 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (470 aa)
	lig3	DNA ligase. (1009 aa)
	rif1	Replication timing regulatory factor 1. (2379 aa)
	rtel1	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1163 aa)
	shld2	FAM35_C domain-containing protein. (814 aa)
	LOC113578292	TINF2_N domain-containing protein. (598 aa)
	LOC113568409	Uncharacterized protein. (419 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1181 aa)
	OTUB2	OTU domain-containing protein. (237 aa)
	mlh1	DNA_mis_repair domain-containing protein. (724 aa)
	pds5a	Uncharacterized protein. (1398 aa)
	LOC113579409	Uncharacterized protein. (439 aa)
	ENSEEEP00000018168	H1 histone family, member X. (187 aa)
	timeless	Timeless circadian clock. (1201 aa)
	LOC113582267	Breast cancer 2, early onset. (2391 aa)
	ENSEEEP00000018711	Zgc:101664. (195 aa)
	pot1	Protection of telomeres 1 homolog. (767 aa)
	ENSEEEP00000019307	Uncharacterized protein. (258 aa)
	pinx1	PIN2 (TERF1) interacting telomerase inhibitor 1. (181 aa)
	ubr5	Ubiquitin protein ligase E3 component n-recognin 5. (2421 aa)
	ercc4	ERCC4 domain-containing protein. (899 aa)
	terf2ip	Telomeric repeat binding factor 2, interacting protein. (536 aa)
	wapl	WAPL domain-containing protein. (1163 aa)
	nat10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1057 aa)
	thoc1	Death domain-containing protein. (652 aa)
	LOC113577208	Uncharacterized protein. (287 aa)
	gtpbp4	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
	flcn	Folliculin. (560 aa)
	gnl3l	CP-type G domain-containing protein. (570 aa)
	fancb	Uncharacterized protein. (822 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DONSON	cdt1	ENSEEEP00000029920	ENSEEEP00000041412	Uncharacterized protein.	Chromatin licensing and DNA replication factor 1.	0.438
ENSEEEP00000006834	ENSEEEP00000019307	ENSEEEP00000006834	ENSEEEP00000019307	Uncharacterized protein.	Uncharacterized protein.	0.927
ENSEEEP00000006834	ENSEEEP00000032310	ENSEEEP00000006834	ENSEEEP00000032310	Uncharacterized protein.	ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.585
ENSEEEP00000006834	LOC113582267	ENSEEEP00000006834	ENSEEEP00000018632	Uncharacterized protein.	Breast cancer 2, early onset.	0.449
ENSEEEP00000006834	atr	ENSEEEP00000006834	ENSEEEP00000033278	Uncharacterized protein.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.680
ENSEEEP00000006834	blm	ENSEEEP00000006834	ENSEEEP00000035037	Uncharacterized protein.	BLM RecQ like helicase.	0.550
ENSEEEP00000006834	ercc4	ENSEEEP00000006834	ENSEEEP00000020903	Uncharacterized protein.	ERCC4 domain-containing protein.	0.973
ENSEEEP00000006834	ercc6	ENSEEEP00000006834	ENSEEEP00000002957	Uncharacterized protein.	Excision repair cross-complementation group 6.	0.558
ENSEEEP00000006834	fancb	ENSEEEP00000006834	ENSEEEP00000026863	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSEEEP00000006834	mlh1	ENSEEEP00000006834	ENSEEEP00000016195	Uncharacterized protein.	DNA_mis_repair domain-containing protein.	0.438
ENSEEEP00000006834	msh2	ENSEEEP00000006834	ENSEEEP00000035660	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.759
ENSEEEP00000006834	msh3	ENSEEEP00000006834	ENSEEEP00000028558	Uncharacterized protein.	MutS homolog 3 (E. coli).	0.575
ENSEEEP00000006834	msh6	ENSEEEP00000006834	ENSEEEP00000046345	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.621
ENSEEEP00000006834	ogg1	ENSEEEP00000006834	ENSEEEP00000000611	Uncharacterized protein.	8-oxoguanine DNA glycosylase.	0.503
ENSEEEP00000006834	parp3	ENSEEEP00000006834	ENSEEEP00000052156	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.505
ENSEEEP00000006834	rmi2	ENSEEEP00000006834	ENSEEEP00000001083	Uncharacterized protein.	Uncharacterized protein.	0.429
ENSEEEP00000006834	rtel1	ENSEEEP00000006834	ENSEEEP00000009043	Uncharacterized protein.	Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...]	0.553
ENSEEEP00000006834	xrcc1	ENSEEEP00000006834	ENSEEEP00000030211	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.508
ENSEEEP00000006834	xrcc5	ENSEEEP00000006834	ENSEEEP00000044169	Uncharacterized protein.	Ku domain-containing protein.	0.502
ENSEEEP00000007003	ENSEEEP00000019307	ENSEEEP00000007003	ENSEEEP00000019307	AAA_23 domain-containing protein.	Uncharacterized protein.	0.480