(26 nodes) Actin-mediated cell contraction network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113586031	Sodium channel, voltage-gated, type I, beta b. (229 aa)
	ENSEEEP00000016065	LIM and calponin homology domains 1a. (873 aa)
	scn2b	Voltage-gated sodium channel beta subunit 2. (218 aa)
	scn4b	Sodium channel, voltage-gated, type IV, beta a. (243 aa)
	nup155	Uncharacterized protein. (1391 aa)
	LOC113575982	Uncharacterized protein. (223 aa)
	LOC113574409	Ig-like domain-containing protein. (209 aa)
	LOC113590296	Uncharacterized protein. (152 aa)
	scn3b	Sodium channel, voltage-gated, type III, beta. (239 aa)
	kcne4	Uncharacterized protein. (187 aa)
	frmd6	FERM domain-containing protein. (609 aa)
	LOC113585869	Ependymin-like 1. (212 aa)
	LOC113589141	Sodium channel, voltage-gated, type IV, beta b. (238 aa)
	ENSEEEP00000037399	Ion_trans domain-containing protein; Belongs to the potassium channel family. (375 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (460 aa)
	LOC113587537	FERM domain-containing protein. (430 aa)
	LOC113585274	Ependymin-like 2. (238 aa)
	LOC113567905	Uncharacterized protein. (128 aa)
	shtn1	Shootin 1. (470 aa)
	ENSEEEP00000046256	Uncharacterized protein. (136 aa)
	ENSEEEP00000046270	Coiled-coil domain containing 88C. (1003 aa)
	epdr1	Uncharacterized protein. (213 aa)
	KCNE2	Uncharacterized protein. (124 aa)
	ENSEEEP00000050727	Calponin-homology (CH) domain-containing protein. (141 aa)
	ENSEEEP00000050729	DUF4757 domain-containing protein. (187 aa)
	LOC113581404	FERM domain-containing protein. (571 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000037399	KCNE2	ENSEEEP00000037399	ENSEEEP00000050383	Ion_trans domain-containing protein; Belongs to the potassium channel family.	Uncharacterized protein.	0.731
ENSEEEP00000037399	LOC113567905	ENSEEEP00000037399	ENSEEEP00000046050	Ion_trans domain-containing protein; Belongs to the potassium channel family.	Uncharacterized protein.	0.978
ENSEEEP00000037399	kcne4	ENSEEEP00000037399	ENSEEEP00000033985	Ion_trans domain-containing protein; Belongs to the potassium channel family.	Uncharacterized protein.	0.672
ENSEEEP00000046256	ENSEEEP00000046270	ENSEEEP00000046256	ENSEEEP00000046270	Uncharacterized protein.	Coiled-coil domain containing 88C.	0.874
ENSEEEP00000046270	ENSEEEP00000046256	ENSEEEP00000046270	ENSEEEP00000046256	Coiled-coil domain containing 88C.	Uncharacterized protein.	0.874
ENSEEEP00000050727	ENSEEEP00000050729	ENSEEEP00000050727	ENSEEEP00000050729	Calponin-homology (CH) domain-containing protein.	DUF4757 domain-containing protein.	0.609
ENSEEEP00000050729	ENSEEEP00000050727	ENSEEEP00000050729	ENSEEEP00000050727	DUF4757 domain-containing protein.	Calponin-homology (CH) domain-containing protein.	0.609
KCNE2	ENSEEEP00000037399	ENSEEEP00000050383	ENSEEEP00000037399	Uncharacterized protein.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.731
KCNE2	KCNQ1	ENSEEEP00000050383	ENSEEEP00000039495	Uncharacterized protein.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.731
KCNE2	LOC113589141	ENSEEEP00000050383	ENSEEEP00000037376	Uncharacterized protein.	Sodium channel, voltage-gated, type IV, beta b.	0.416
KCNE2	kcne4	ENSEEEP00000050383	ENSEEEP00000033985	Uncharacterized protein.	Uncharacterized protein.	0.581
KCNE2	scn3b	ENSEEEP00000050383	ENSEEEP00000033933	Uncharacterized protein.	Sodium channel, voltage-gated, type III, beta.	0.416
KCNE2	scn4b	ENSEEEP00000050383	ENSEEEP00000018624	Uncharacterized protein.	Sodium channel, voltage-gated, type IV, beta a.	0.574
KCNQ1	KCNE2	ENSEEEP00000039495	ENSEEEP00000050383	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	Uncharacterized protein.	0.731
KCNQ1	LOC113567905	ENSEEEP00000039495	ENSEEEP00000046050	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	Uncharacterized protein.	0.797
KCNQ1	kcne4	ENSEEEP00000039495	ENSEEEP00000033985	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	Uncharacterized protein.	0.672
KCNQ1	scn3b	ENSEEEP00000039495	ENSEEEP00000033933	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	Sodium channel, voltage-gated, type III, beta.	0.497
KCNQ1	scn4b	ENSEEEP00000039495	ENSEEEP00000018624	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	Sodium channel, voltage-gated, type IV, beta a.	0.470
LOC113567905	ENSEEEP00000037399	ENSEEEP00000046050	ENSEEEP00000037399	Uncharacterized protein.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.978
LOC113567905	KCNQ1	ENSEEEP00000046050	ENSEEEP00000039495	Uncharacterized protein.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.797