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| | mgme1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (338 aa) |
| | PLD4 | Uncharacterized protein. (504 aa) |
| | hormad1 | HORMA domain containing 1. (349 aa) |
| | dis3l | RNB domain-containing protein; Belongs to the RNR ribonuclease family. (1056 aa) |
| | endog | Endonuclease. (308 aa) |
| | enpp1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (835 aa) |
| | ENSEEEP00000043756 | XPGI domain-containing protein. (341 aa) |
| | ddx1 | Uncharacterized protein. (740 aa) |
| | dnase1 | Deoxyribonuclease; Belongs to the DNase I family. (280 aa) |
| | LOC113567770 | Uncharacterized protein. (591 aa) |
| | rag1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1085 aa) |
| | nthl1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (497 aa) |
| | LOC113567584 | Uncharacterized protein. (377 aa) |
| | ENSEEEP00000037636 | Helicase C-terminal domain-containing protein. (432 aa) |
| | ENSEEEP00000037634 | ERCC4 domain-containing protein. (1166 aa) |
| | xpa | Xeroderma pigmentosum, complementation group A. (519 aa) |
| | LOC113583536 | Argonaute RISC catalytic component 1; Belongs to the argonaute family. (864 aa) |
| | LOC113583535 | Argonaute RISC catalytic component 3a; Belongs to the argonaute family. (818 aa) |
| | LOC113572557 | XendoU domain-containing protein. (289 aa) |
| | smg6 | SMG6 nonsense mediated mRNA decay factor. (1575 aa) |
| | ENSEEEP00000036318 | Uncharacterized protein. (146 aa) |
| | ENSEEEP00000036317 | NUC domain-containing protein. (434 aa) |
| | ankle1 | Zgc:85936. (862 aa) |
| | cstf2 | RRM domain-containing protein. (506 aa) |
| | ENSEEEP00000035317 | Zgc:165656. (272 aa) |
| | ENSEEEP00000035283 | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (118 aa) |
| | eri1 | Exoribonuclease 1. (335 aa) |
| | LOC113574523 | Uncharacterized protein. (165 aa) |
| | rbbp8 | SAE2 domain-containing protein. (131 aa) |
| | LOC113580907 | Endoplasmic reticulum to nucleus signaling 2. (876 aa) |
| | usb1 | U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (286 aa) |
| | nob1 | RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (438 aa) |
| | rnasek | Uncharacterized protein. (101 aa) |
| | utp23 | Uncharacterized protein. (254 aa) |
| | LOC113581116 | Deoxyribonuclease; Belongs to the DNase I family. (294 aa) |
| | LOC113576618 | Ribonuclease P and MRP subunit p25, b. (179 aa) |
| | LOC113590030 | Uncharacterized protein. (347 aa) |
| | bivm | Uncharacterized protein. (505 aa) |
| | xrn1 | 5'-3' exoribonuclease 1. (1689 aa) |
| | dicer1 | Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1876 aa) |
| | LOC113586234 | C3H1-type domain-containing protein. (589 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | LOC113570817 | Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (803 aa) |
| | polr2i | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa) |
| | ENSEEEP00000031728 | Uncharacterized protein. (384 aa) |
| | rida | Uncharacterized protein. (136 aa) |
| | abt1 | Uncharacterized protein. (286 aa) |
| | pop1 | POP1 homolog, ribonuclease P/MRP subunit. (889 aa) |
| | rpp30 | Uncharacterized protein. (266 aa) |
| | exosc3 | KH_dom_type_1 domain-containing protein. (245 aa) |
| | Exd1 | 3'-5' exonuclease domain-containing protein. (378 aa) |
| | ISG20L2 | Exonuclease domain-containing protein. (324 aa) |
| | LOC113573356 | Si:dkeyp-110e4.6. (527 aa) |
| | n4bp1 | RNase_Zc3h12a domain-containing protein. (844 aa) |
| | tsen2 | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (472 aa) |
| | pan3 | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (797 aa) |
| | ENSEEEP00000039119 | Uncharacterized protein. (260 aa) |
| | LOC113577337 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (263 aa) |
| | dbr1 | Debranching RNA lariats 1. (560 aa) |
| | znrd1 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (118 aa) |
| | rcl1 | Uncharacterized protein. (373 aa) |
| | cnot2 | NOT2_3_5 domain-containing protein. (531 aa) |
| | cnot6 | CCR4-NOT transcription complex, subunit 6a. (556 aa) |
| | tbl3 | WD_REPEATS_REGION domain-containing protein. (915 aa) |
| | cnot8 | Uncharacterized protein. (285 aa) |
| | ercc1 | Uncharacterized protein. (346 aa) |
| | elac2 | ElaC ribonuclease Z 2. (837 aa) |
| | exosc10 | HRDC domain-containing protein. (887 aa) |
| | nol9 | CLP1_P domain-containing protein. (725 aa) |
| | LOC113580343 | C3H1-type domain-containing protein. (888 aa) |
| | eri2 | ERI1 exoribonuclease family member 2. (470 aa) |
| | ENSEEEP00000042202 | Exonuclease domain-containing protein. (294 aa) |
| | LOC113571916 | Uncharacterized protein. (372 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (615 aa) |
| | LOC113579207 | Uncharacterized protein. (286 aa) |
| | parn | R3H domain-containing protein. (648 aa) |
| | rexo4 | Exonuclease domain-containing protein. (432 aa) |
| | dcp2 | Nudix hydrolase domain-containing protein. (398 aa) |
| | ENSEEEP00000029089 | Uncharacterized protein. (177 aa) |
| | LOC113589524 | RECA_2 domain-containing protein. (121 aa) |
| | LOC113575016 | Ankyrin repeat domain 31. (219 aa) |
| | DNASE1L3 | Endo/exonuclease/phosphatase domain-containing protein. (338 aa) |
| | prorp | PRORP domain-containing protein. (577 aa) |
| | ybey | Uncharacterized protein. (169 aa) |
| | ENSEEEP00000027215 | XPGN domain-containing protein. (302 aa) |
| | Ercc5 | XPGI domain-containing protein. (396 aa) |
| | pld3 | Uncharacterized protein. (494 aa) |
| | LACTB2 | Lactamase_B domain-containing protein. (286 aa) |
| | snd1 | Uncharacterized protein. (776 aa) |
| | PNPT1 | S1 motif domain-containing protein. (769 aa) |
| | tsn | Uncharacterized protein. (227 aa) |
| | ENSEEEP00000025109 | Meiosis-specific, MEI4 homolog (S. cerevisiae). (303 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa) |
| | mblac1 | Lactamase_B domain-containing protein. (224 aa) |
| | LOC113580795 | Uncharacterized protein. (101 aa) |
| | enpp2 | Ectonucleotide pyrophosphatase/phosphodiesterase 2. (858 aa) |
| | rexo2 | Exonuclease domain-containing protein. (270 aa) |
| | LOC113574810 | AP_endonuc_2 domain-containing protein. (328 aa) |
| | ercc3 | Uncharacterized protein. (823 aa) |
| | LOC113568050 | Uncharacterized protein. (308 aa) |
| | exd3 | Exonuclease 3'-5' domain containing 3. (689 aa) |
| | pde12 | Endo/exonuclease/phosphatase domain-containing protein. (581 aa) |
| | endou | Endonuclease, polyU-specific. (350 aa) |
| | TATDN3 | Uncharacterized protein. (269 aa) |
| | ercc4 | ERCC4 domain-containing protein. (899 aa) |
| | cpsf3 | Uncharacterized protein. (691 aa) |
| | LOC113574413 | Uncharacterized protein. (682 aa) |
| | LOC113584053 | Endonuclease, polyU-specific 2. (278 aa) |
| | dcp1b | mRNA_decap_C domain-containing protein. (547 aa) |
| | LOC113578936 | Uncharacterized protein. (296 aa) |
| | cpsf6 | RRM domain-containing protein. (565 aa) |
| | tatdn2 | TatD DNase domain containing 2. (632 aa) |
| | rnaseh1 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (283 aa) |
| | cunh12orf10 | Uncharacterized protein. (404 aa) |
| | exo1 | Exonuclease 1. (771 aa) |
| | ENSEEEP00000019655 | RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (148 aa) |
| | xrn2 | 5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (972 aa) |
| | ENSEEEP00000050044 | TatD DNase domain containing 3. (240 aa) |
| | ENSEEEP00000050384 | Si:dkey-243k1.3. (273 aa) |
| | Trir | Telomerase RNA component interacting RNase. (153 aa) |
| | ENSEEEP00000050839 | Metallophos domain-containing protein. (106 aa) |
| | zc3h12a | C3H1-type domain-containing protein. (598 aa) |
| | LOC113582966 | Fip1 domain-containing protein. (550 aa) |
| | rrp36 | Uncharacterized protein. (348 aa) |
| | eme1 | Essential meiotic structure-specific endonuclease 1. (550 aa) |
| | LOC113569782 | Uncharacterized protein; Belongs to the RNase T2 family. (263 aa) |
| | ercc2 | Helicase ATP-binding domain-containing protein. (760 aa) |
| | nop9 | Uncharacterized protein. (586 aa) |
| | rad1 | Uncharacterized protein. (279 aa) |
| | exo5 | Uncharacterized protein. (392 aa) |
| | LOC113580654 | Endo/exonuclease/phosphatase domain-containing protein. (788 aa) |
| | cpsf2 | Cleavage and polyadenylation specificity factor subunit 2. (787 aa) |
| | rnaset2 | Uncharacterized protein; Belongs to the RNase T2 family. (245 aa) |
| | nudt12 | Uncharacterized protein. (442 aa) |
| | ENSEEEP00000018543 | Methionine sulfoxide reductase B1b. (259 aa) |
| | LOC113579999 | Tudor domain-containing protein. (184 aa) |
| | ENSEEEP00000017959 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (784 aa) |
| | ENSEEEP00000017953 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (368 aa) |
| | Pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (708 aa) |
| | ENSEEEP00000017941 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (304 aa) |
| | Helz2 | AAA_11 domain-containing protein. (537 aa) |
| | helz2 | AAA_12 domain-containing protein. (221 aa) |
| | ENSEEEP00000017001 | Endonuclease_NS domain-containing protein. (171 aa) |
| | ttc38 | Uncharacterized protein. (483 aa) |
| | ENSEEEP00000016716 | Helicase ATP-binding domain-containing protein. (320 aa) |
| | ENSEEEP00000016690 | Phospholipase D family, member 6. (207 aa) |
| | dclre1b | DNA cross-link repair 1B. (580 aa) |
| | elac1 | Uncharacterized protein. (439 aa) |
| | kri1 | KRI1 homolog. (729 aa) |
| | exosc9 | Uncharacterized protein. (388 aa) |
| | rpp40 | Uncharacterized protein. (360 aa) |
| | rpp14 | Uncharacterized protein. (124 aa) |
| | ago4 | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (882 aa) |
| | nhp2 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa) |
| | EXOG | Uncharacterized protein. (355 aa) |
| | LOC113568479 | RNase_Zc3h12a domain-containing protein. (857 aa) |
| | LOC113578373 | Argonaute RISC catalytic component 3b; Belongs to the argonaute family. (859 aa) |
| | Ang | RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (156 aa) |
| | spo11 | SPO11 meiotic protein covalently bound to DSB. (368 aa) |
| | pop5 | Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (171 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1181 aa) |
| | zc3h12b | Zinc finger CCCH-type containing 12B. (870 aa) |
| | ENSEEEP00000013350 | Uncharacterized protein. (106 aa) |
| | exosc8 | Uncharacterized protein. (281 aa) |
| | dclre1a | DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (951 aa) |
| | LOC113569971 | Deoxyribonuclease I-like 1. (329 aa) |
| | tdp1 | Uncharacterized protein. (622 aa) |
| | MARF1 | Meiosis regulator and mRNA stability factor 1. (1669 aa) |
| | ENSEEEP00000011546 | Uncharacterized protein. (890 aa) |
| | bms1 | Bms1-type G domain-containing protein. (1274 aa) |
| | exosc2 | Uncharacterized protein. (295 aa) |
| | cpsf4 | Uncharacterized protein. (269 aa) |
| | dis3 | Uncharacterized protein; Belongs to the RNR ribonuclease family. (948 aa) |
| | gnl3 | CP-type G domain-containing protein. (557 aa) |
| | pan2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1209 aa) |
| | ENDOV | Endonuclease V. (238 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1002 aa) |
| | aptx | HIT domain-containing protein. (381 aa) |
| | LOC113589972 | XendoU domain-containing protein. (307 aa) |
| | ENSEEEP00000008399 | Ig-like domain-containing protein. (165 aa) |
| | dclre1c | DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (683 aa) |
| | pcf11 | PCF11, cleavage and polyadenylation factor subunit. (1483 aa) |
| | mrpl44 | Uncharacterized protein. (334 aa) |
| | DXO | RAI1 domain-containing protein. (416 aa) |
| | exosc7 | Uncharacterized protein. (291 aa) |
| | tatdn1 | Uncharacterized protein. (316 aa) |
| | ENSEEEP00000007004 | Uncharacterized protein. (286 aa) |
| | ENSEEEP00000007003 | AAA_23 domain-containing protein. (53 aa) |
| | ENSEEEP00000006834 | Uncharacterized protein. (110 aa) |
| | rpp38 | Ribonuclease P/MRP 38 subunit. (260 aa) |
| | rnaseh2a | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (249 aa) |
| | LOC113569058 | AAA_23 domain-containing protein. (469 aa) |
| | dis3l2 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (923 aa) |
| | LOC113589333 | Uncharacterized protein. (809 aa) |
| | LOC113568250 | RAD51 paralog C. (260 aa) |
| | noct | Endo/exonuclease/phosphatase domain-containing protein. (443 aa) |
| | dcp1a | Decapping mRNA 1A. (441 aa) |
| | apex1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (312 aa) |
| | ASTE1 | XPG_I_2 domain-containing protein. (697 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (616 aa) |
| | ern1 | Uncharacterized protein. (1020 aa) |
| | pold1 | DNA polymerase. (1061 aa) |
| | ENSEEEP00000002024 | Uncharacterized protein. (150 aa) |
| | polr3k | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa) |
| | CPSF7 | RRM domain-containing protein. (450 aa) |
| | ENSEEEP00000001936 | RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (134 aa) |
| | ENSEEEP00000001700 | Uncharacterized protein. (248 aa) |
| | cnot6l | Endo/exonuclease/phosphatase domain-containing protein. (553 aa) |
| | dffb | DNA fragmentation factor, beta polypeptide (caspase-activated DNase). (333 aa) |
| | LOC113581528 | Endo/exonuclease/phosphatase domain-containing protein. (558 aa) |
| | LOC113569619 | Uncharacterized protein. (202 aa) |
| | ENSEEEP00000001158 | RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (152 aa) |
| | tsr1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae). (817 aa) |
| | LOC113568197 | Uncharacterized protein. (268 aa) |
| | ogg1 | 8-oxoguanine DNA glycosylase. (389 aa) |
| | piwil1 | Uncharacterized protein; Belongs to the argonaute family. (858 aa) |
| | zranb3 | Zinc finger, RAN-binding domain containing 3. (1057 aa) |
| | angel2 | Endo/exonuclease/phosphatase domain-containing protein. (586 aa) |
| | LOC113576894 | RRM domain-containing protein. (795 aa) |
| | drosha | Uncharacterized protein. (1332 aa) |
| | LOC113572244 | Endo/exonuclease/phosphatase domain-containing protein. (409 aa) |
| | apex2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (567 aa) |
| | fan1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1005 aa) |
| | tsen34 | tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (326 aa) |
| | edc4 | Enhancer of mRNA decapping 4. (1346 aa) |
| | dnase2b | Uncharacterized protein. (350 aa) |
| | pelo | Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (386 aa) |
| | ago2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (864 aa) |
| | edc3 | Uncharacterized protein. (504 aa) |
| | Piwil2 | Piwi domain-containing protein. (288 aa) |
| | ENSEEEP00000046229 | Uncharacterized protein. (283 aa) |
| | polg | POLAc domain-containing protein. (1200 aa) |
| | toe1 | Target of EGR1, exonuclease. (467 aa) |
| | LOC113585308 | Interferon stimulated exonuclease gene. (305 aa) |
