STRINGSTRING
mgme1 mgme1 zranb3 zranb3 piwil1 piwil1 ogg1 ogg1 LOC113568197 LOC113568197 tsr1 tsr1 ENSEEEP00000001158 ENSEEEP00000001158 LOC113569619 LOC113569619 LOC113581528 LOC113581528 dffb dffb cnot6l cnot6l ENSEEEP00000001700 ENSEEEP00000001700 ENSEEEP00000001936 ENSEEEP00000001936 CPSF7 CPSF7 polr3k polr3k ENSEEEP00000002024 ENSEEEP00000002024 pold1 pold1 ern1 ern1 exd2 exd2 ASTE1 ASTE1 apex1 apex1 dcp1a dcp1a noct noct LOC113568250 LOC113568250 LOC113589333 LOC113589333 dis3l2 dis3l2 LOC113569058 LOC113569058 rnaseh2a rnaseh2a rpp38 rpp38 ENSEEEP00000006834 ENSEEEP00000006834 ENSEEEP00000007003 ENSEEEP00000007003 ENSEEEP00000007004 ENSEEEP00000007004 tatdn1 tatdn1 exosc7 exosc7 DXO DXO mrpl44 mrpl44 pcf11 pcf11 dclre1c dclre1c ENSEEEP00000008399 ENSEEEP00000008399 LOC113589972 LOC113589972 aptx aptx DNA2 DNA2 ENDOV ENDOV pan2 pan2 gnl3 gnl3 dis3 dis3 cpsf4 cpsf4 exosc2 exosc2 bms1 bms1 ENSEEEP00000011546 ENSEEEP00000011546 MARF1 MARF1 tdp1 tdp1 LOC113569971 LOC113569971 dclre1a dclre1a exosc8 exosc8 ENSEEEP00000013350 ENSEEEP00000013350 zc3h12b zc3h12b rad50 rad50 pop5 pop5 spo11 spo11 Ang Ang LOC113578373 LOC113578373 LOC113568479 LOC113568479 EXOG EXOG nhp2 nhp2 ago4 ago4 rpp14 rpp14 rpp40 rpp40 exosc9 exosc9 kri1 kri1 elac1 elac1 dclre1b dclre1b ENSEEEP00000016690 ENSEEEP00000016690 ENSEEEP00000016716 ENSEEEP00000016716 ttc38 ttc38 ENSEEEP00000017001 ENSEEEP00000017001 helz2 helz2 Helz2 Helz2 ENSEEEP00000017941 ENSEEEP00000017941 Pole Pole ENSEEEP00000017953 ENSEEEP00000017953 ENSEEEP00000017959 ENSEEEP00000017959 LOC113579999 LOC113579999 ENSEEEP00000018543 ENSEEEP00000018543 nudt12 nudt12 rnaset2 rnaset2 cpsf2 cpsf2 LOC113580654 LOC113580654 xrn2 xrn2 ENSEEEP00000019655 ENSEEEP00000019655 exo1 exo1 cunh12orf10 cunh12orf10 rnaseh1 rnaseh1 tatdn2 tatdn2 cpsf6 cpsf6 LOC113578936 LOC113578936 dcp1b dcp1b LOC113584053 LOC113584053 LOC113574413 LOC113574413 cpsf3 cpsf3 ercc4 ercc4 TATDN3 TATDN3 endou endou pde12 pde12 exd3 exd3 LOC113568050 LOC113568050 ercc3 ercc3 LOC113574810 LOC113574810 rexo2 rexo2 enpp2 enpp2 LOC113580795 LOC113580795 mblac1 mblac1 mre11 mre11 ENSEEEP00000025109 ENSEEEP00000025109 tsn tsn PNPT1 PNPT1 snd1 snd1 LACTB2 LACTB2 pld3 pld3 Ercc5 Ercc5 ENSEEEP00000027215 ENSEEEP00000027215 ybey ybey prorp prorp DNASE1L3 DNASE1L3 LOC113575016 LOC113575016 LOC113589524 LOC113589524 ENSEEEP00000029089 ENSEEEP00000029089 pan3 pan3 tsen2 tsen2 n4bp1 n4bp1 LOC113573356 LOC113573356 ISG20L2 ISG20L2 Exd1 Exd1 exosc3 exosc3 rpp30 rpp30 pop1 pop1 abt1 abt1 rida rida ENSEEEP00000031728 ENSEEEP00000031728 polr2i polr2i LOC113570817 LOC113570817 fen1 fen1 LOC113586234 LOC113586234 dicer1 dicer1 xrn1 xrn1 bivm bivm LOC113590030 LOC113590030 LOC113576618 LOC113576618 LOC113581116 LOC113581116 utp23 utp23 rnasek rnasek nob1 nob1 usb1 usb1 LOC113580907 LOC113580907 rbbp8 rbbp8 LOC113574523 LOC113574523 eri1 eri1 ENSEEEP00000035283 ENSEEEP00000035283 ENSEEEP00000035317 ENSEEEP00000035317 cstf2 cstf2 ankle1 ankle1 ENSEEEP00000036317 ENSEEEP00000036317 ENSEEEP00000036318 ENSEEEP00000036318 smg6 smg6 LOC113572557 LOC113572557 LOC113583535 LOC113583535 LOC113583536 LOC113583536 xpa xpa ENSEEEP00000037634 ENSEEEP00000037634 ENSEEEP00000037636 ENSEEEP00000037636 LOC113567584 LOC113567584 nthl1 nthl1 rag1 rag1 LOC113567770 LOC113567770 ENSEEEP00000039119 ENSEEEP00000039119 LOC113577337 LOC113577337 dbr1 dbr1 znrd1 znrd1 rcl1 rcl1 cnot2 cnot2 cnot6 cnot6 tbl3 tbl3 cnot8 cnot8 ercc1 ercc1 elac2 elac2 exosc10 exosc10 nol9 nol9 LOC113580343 LOC113580343 eri2 eri2 ENSEEEP00000042202 ENSEEEP00000042202 LOC113571916 LOC113571916 mus81 mus81 LOC113579207 LOC113579207 parn parn rexo4 rexo4 dcp2 dcp2 nop9 nop9 dnase1 dnase1 ddx1 ddx1 ENSEEEP00000043756 ENSEEEP00000043756 enpp1 enpp1 endog endog dis3l dis3l hormad1 hormad1 PLD4 PLD4 LOC113585308 LOC113585308 toe1 toe1 polg polg ENSEEEP00000046229 ENSEEEP00000046229 Piwil2 Piwil2 edc3 edc3 ago2 ago2 pelo pelo dnase2b dnase2b edc4 edc4 tsen34 tsen34 fan1 fan1 apex2 apex2 LOC113572244 LOC113572244 drosha drosha LOC113576894 LOC113576894 angel2 angel2 ENSEEEP00000050044 ENSEEEP00000050044 ENSEEEP00000050384 ENSEEEP00000050384 Trir Trir ENSEEEP00000050839 ENSEEEP00000050839 zc3h12a zc3h12a LOC113582966 LOC113582966 rrp36 rrp36 eme1 eme1 LOC113569782 LOC113569782 ercc2 ercc2 rad1 rad1 exo5 exo5
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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gene neighborhood
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mgme1Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (338 aa)
zranb3Zinc finger, RAN-binding domain containing 3. (1057 aa)
piwil1Uncharacterized protein; Belongs to the argonaute family. (858 aa)
ogg18-oxoguanine DNA glycosylase. (389 aa)
LOC113568197Uncharacterized protein. (268 aa)
tsr1TSR1, 20S rRNA accumulation, homolog (S. cerevisiae). (817 aa)
ENSEEEP00000001158RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (152 aa)
LOC113569619Uncharacterized protein. (202 aa)
LOC113581528Endo/exonuclease/phosphatase domain-containing protein. (558 aa)
dffbDNA fragmentation factor, beta polypeptide (caspase-activated DNase). (333 aa)
cnot6lEndo/exonuclease/phosphatase domain-containing protein. (553 aa)
ENSEEEP00000001700Uncharacterized protein. (248 aa)
ENSEEEP00000001936RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (134 aa)
CPSF7RRM domain-containing protein. (450 aa)
polr3kDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
ENSEEEP00000002024Uncharacterized protein. (150 aa)
pold1DNA polymerase. (1061 aa)
ern1Uncharacterized protein. (1020 aa)
exd2Exonuclease 3'-5' domain containing 2. (616 aa)
ASTE1XPG_I_2 domain-containing protein. (697 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (312 aa)
dcp1aDecapping mRNA 1A. (441 aa)
noctEndo/exonuclease/phosphatase domain-containing protein. (443 aa)
LOC113568250RAD51 paralog C. (260 aa)
LOC113589333Uncharacterized protein. (809 aa)
dis3l2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (923 aa)
LOC113569058AAA_23 domain-containing protein. (469 aa)
rnaseh2aRibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (249 aa)
rpp38Ribonuclease P/MRP 38 subunit. (260 aa)
ENSEEEP00000006834Uncharacterized protein. (110 aa)
ENSEEEP00000007003AAA_23 domain-containing protein. (53 aa)
ENSEEEP00000007004Uncharacterized protein. (286 aa)
tatdn1Uncharacterized protein. (316 aa)
exosc7Uncharacterized protein. (291 aa)
DXORAI1 domain-containing protein. (416 aa)
mrpl44Uncharacterized protein. (334 aa)
pcf11PCF11, cleavage and polyadenylation factor subunit. (1483 aa)
dclre1cDNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (683 aa)
ENSEEEP00000008399Ig-like domain-containing protein. (165 aa)
LOC113589972XendoU domain-containing protein. (307 aa)
aptxHIT domain-containing protein. (381 aa)
DNA2DNA replication helicase/nuclease 2. (1002 aa)
ENDOVEndonuclease V. (238 aa)
pan2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1209 aa)
gnl3CP-type G domain-containing protein. (557 aa)
dis3Uncharacterized protein; Belongs to the RNR ribonuclease family. (948 aa)
cpsf4Uncharacterized protein. (269 aa)
exosc2Uncharacterized protein. (295 aa)
bms1Bms1-type G domain-containing protein. (1274 aa)
ENSEEEP00000011546Uncharacterized protein. (890 aa)
MARF1Meiosis regulator and mRNA stability factor 1. (1669 aa)
tdp1Uncharacterized protein. (622 aa)
LOC113569971Deoxyribonuclease I-like 1. (329 aa)
dclre1aDNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (951 aa)
exosc8Uncharacterized protein. (281 aa)
ENSEEEP00000013350Uncharacterized protein. (106 aa)
zc3h12bZinc finger CCCH-type containing 12B. (870 aa)
rad50RAD50 homolog, double strand break repair protein. (1181 aa)
pop5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (171 aa)
spo11SPO11 meiotic protein covalently bound to DSB. (368 aa)
AngRNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (156 aa)
LOC113578373Argonaute RISC catalytic component 3b; Belongs to the argonaute family. (859 aa)
LOC113568479RNase_Zc3h12a domain-containing protein. (857 aa)
EXOGUncharacterized protein. (355 aa)
nhp2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa)
ago4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (882 aa)
rpp14Uncharacterized protein. (124 aa)
rpp40Uncharacterized protein. (360 aa)
exosc9Uncharacterized protein. (388 aa)
kri1KRI1 homolog. (729 aa)
elac1Uncharacterized protein. (439 aa)
dclre1bDNA cross-link repair 1B. (580 aa)
ENSEEEP00000016690Phospholipase D family, member 6. (207 aa)
ENSEEEP00000016716Helicase ATP-binding domain-containing protein. (320 aa)
ttc38Uncharacterized protein. (483 aa)
ENSEEEP00000017001Endonuclease_NS domain-containing protein. (171 aa)
helz2AAA_12 domain-containing protein. (221 aa)
Helz2AAA_11 domain-containing protein. (537 aa)
ENSEEEP00000017941DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (304 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (708 aa)
ENSEEEP00000017953DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (368 aa)
ENSEEEP00000017959ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (784 aa)
LOC113579999Tudor domain-containing protein. (184 aa)
ENSEEEP00000018543Methionine sulfoxide reductase B1b. (259 aa)
nudt12Uncharacterized protein. (442 aa)
rnaset2Uncharacterized protein; Belongs to the RNase T2 family. (245 aa)
cpsf2Cleavage and polyadenylation specificity factor subunit 2. (787 aa)
LOC113580654Endo/exonuclease/phosphatase domain-containing protein. (788 aa)
xrn25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (972 aa)
ENSEEEP00000019655RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (148 aa)
exo1Exonuclease 1. (771 aa)
cunh12orf10Uncharacterized protein. (404 aa)
rnaseh1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (283 aa)
tatdn2TatD DNase domain containing 2. (632 aa)
cpsf6RRM domain-containing protein. (565 aa)
LOC113578936Uncharacterized protein. (296 aa)
dcp1bmRNA_decap_C domain-containing protein. (547 aa)
LOC113584053Endonuclease, polyU-specific 2. (278 aa)
LOC113574413Uncharacterized protein. (682 aa)
cpsf3Uncharacterized protein. (691 aa)
ercc4ERCC4 domain-containing protein. (899 aa)
TATDN3Uncharacterized protein. (269 aa)
endouEndonuclease, polyU-specific. (350 aa)
pde12Endo/exonuclease/phosphatase domain-containing protein. (581 aa)
exd3Exonuclease 3'-5' domain containing 3. (689 aa)
LOC113568050Uncharacterized protein. (308 aa)
ercc3Uncharacterized protein. (823 aa)
LOC113574810AP_endonuc_2 domain-containing protein. (328 aa)
rexo2Exonuclease domain-containing protein. (270 aa)
enpp2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (858 aa)
LOC113580795Uncharacterized protein. (101 aa)
mblac1Lactamase_B domain-containing protein. (224 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
ENSEEEP00000025109Meiosis-specific, MEI4 homolog (S. cerevisiae). (303 aa)
tsnUncharacterized protein. (227 aa)
PNPT1S1 motif domain-containing protein. (769 aa)
snd1Uncharacterized protein. (776 aa)
LACTB2Lactamase_B domain-containing protein. (286 aa)
pld3Uncharacterized protein. (494 aa)
Ercc5XPGI domain-containing protein. (396 aa)
ENSEEEP00000027215XPGN domain-containing protein. (302 aa)
ybeyUncharacterized protein. (169 aa)
prorpPRORP domain-containing protein. (577 aa)
DNASE1L3Endo/exonuclease/phosphatase domain-containing protein. (338 aa)
LOC113575016Ankyrin repeat domain 31. (219 aa)
LOC113589524RECA_2 domain-containing protein. (121 aa)
ENSEEEP00000029089Uncharacterized protein. (177 aa)
pan3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (797 aa)
tsen2tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (472 aa)
n4bp1RNase_Zc3h12a domain-containing protein. (844 aa)
LOC113573356Si:dkeyp-110e4.6. (527 aa)
ISG20L2Exonuclease domain-containing protein. (324 aa)
Exd13'-5' exonuclease domain-containing protein. (378 aa)
exosc3KH_dom_type_1 domain-containing protein. (245 aa)
rpp30Uncharacterized protein. (266 aa)
pop1POP1 homolog, ribonuclease P/MRP subunit. (889 aa)
abt1Uncharacterized protein. (286 aa)
ridaUncharacterized protein. (136 aa)
ENSEEEP00000031728Uncharacterized protein. (384 aa)
polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
LOC113570817Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (803 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
LOC113586234C3H1-type domain-containing protein. (589 aa)
dicer1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1876 aa)
xrn15'-3' exoribonuclease 1. (1689 aa)
bivmUncharacterized protein. (505 aa)
LOC113590030Uncharacterized protein. (347 aa)
LOC113576618Ribonuclease P and MRP subunit p25, b. (179 aa)
LOC113581116Deoxyribonuclease; Belongs to the DNase I family. (294 aa)
utp23Uncharacterized protein. (254 aa)
rnasekUncharacterized protein. (101 aa)
nob1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (438 aa)
usb1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (286 aa)
LOC113580907Endoplasmic reticulum to nucleus signaling 2. (876 aa)
rbbp8SAE2 domain-containing protein. (131 aa)
LOC113574523Uncharacterized protein. (165 aa)
eri1Exoribonuclease 1. (335 aa)
ENSEEEP00000035283Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (118 aa)
ENSEEEP00000035317Zgc:165656. (272 aa)
cstf2RRM domain-containing protein. (506 aa)
ankle1Zgc:85936. (862 aa)
ENSEEEP00000036317NUC domain-containing protein. (434 aa)
ENSEEEP00000036318Uncharacterized protein. (146 aa)
smg6SMG6 nonsense mediated mRNA decay factor. (1575 aa)
LOC113572557XendoU domain-containing protein. (289 aa)
LOC113583535Argonaute RISC catalytic component 3a; Belongs to the argonaute family. (818 aa)
LOC113583536Argonaute RISC catalytic component 1; Belongs to the argonaute family. (864 aa)
xpaXeroderma pigmentosum, complementation group A. (519 aa)
ENSEEEP00000037634ERCC4 domain-containing protein. (1166 aa)
ENSEEEP00000037636Helicase C-terminal domain-containing protein. (432 aa)
LOC113567584Uncharacterized protein. (377 aa)
nthl1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (497 aa)
rag1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1085 aa)
LOC113567770Uncharacterized protein. (591 aa)
ENSEEEP00000039119Uncharacterized protein. (260 aa)
LOC113577337Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (263 aa)
dbr1Debranching RNA lariats 1. (560 aa)
znrd1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (118 aa)
rcl1Uncharacterized protein. (373 aa)
cnot2NOT2_3_5 domain-containing protein. (531 aa)
cnot6CCR4-NOT transcription complex, subunit 6a. (556 aa)
tbl3WD_REPEATS_REGION domain-containing protein. (915 aa)
cnot8Uncharacterized protein. (285 aa)
ercc1Uncharacterized protein. (346 aa)
elac2ElaC ribonuclease Z 2. (837 aa)
exosc10HRDC domain-containing protein. (887 aa)
nol9CLP1_P domain-containing protein. (725 aa)
LOC113580343C3H1-type domain-containing protein. (888 aa)
eri2ERI1 exoribonuclease family member 2. (470 aa)
ENSEEEP00000042202Exonuclease domain-containing protein. (294 aa)
LOC113571916Uncharacterized protein. (372 aa)
mus81MUS81 structure-specific endonuclease subunit. (615 aa)
LOC113579207Uncharacterized protein. (286 aa)
parnR3H domain-containing protein. (648 aa)
rexo4Exonuclease domain-containing protein. (432 aa)
dcp2Nudix hydrolase domain-containing protein. (398 aa)
nop9Uncharacterized protein. (586 aa)
dnase1Deoxyribonuclease; Belongs to the DNase I family. (280 aa)
ddx1Uncharacterized protein. (740 aa)
ENSEEEP00000043756XPGI domain-containing protein. (341 aa)
enpp1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (835 aa)
endogEndonuclease. (308 aa)
dis3lRNB domain-containing protein; Belongs to the RNR ribonuclease family. (1056 aa)
hormad1HORMA domain containing 1. (349 aa)
PLD4Uncharacterized protein. (504 aa)
LOC113585308Interferon stimulated exonuclease gene. (305 aa)
toe1Target of EGR1, exonuclease. (467 aa)
polgPOLAc domain-containing protein. (1200 aa)
ENSEEEP00000046229Uncharacterized protein. (283 aa)
Piwil2Piwi domain-containing protein. (288 aa)
edc3Uncharacterized protein. (504 aa)
ago2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (864 aa)
peloProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (386 aa)
dnase2bUncharacterized protein. (350 aa)
edc4Enhancer of mRNA decapping 4. (1346 aa)
tsen34tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (326 aa)
fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1005 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (567 aa)
LOC113572244Endo/exonuclease/phosphatase domain-containing protein. (409 aa)
droshaUncharacterized protein. (1332 aa)
LOC113576894RRM domain-containing protein. (795 aa)
angel2Endo/exonuclease/phosphatase domain-containing protein. (586 aa)
ENSEEEP00000050044TatD DNase domain containing 3. (240 aa)
ENSEEEP00000050384Si:dkey-243k1.3. (273 aa)
TrirTelomerase RNA component interacting RNase. (153 aa)
ENSEEEP00000050839Metallophos domain-containing protein. (106 aa)
zc3h12aC3H1-type domain-containing protein. (598 aa)
LOC113582966Fip1 domain-containing protein. (550 aa)
rrp36Uncharacterized protein. (348 aa)
eme1Essential meiotic structure-specific endonuclease 1. (550 aa)
LOC113569782Uncharacterized protein; Belongs to the RNase T2 family. (263 aa)
ercc2Helicase ATP-binding domain-containing protein. (760 aa)
rad1Uncharacterized protein. (279 aa)
exo5Uncharacterized protein. (392 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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