(33 nodes) Integral component of presynaptic membrane network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113568654	Uncharacterized protein. (326 aa)
	syt7	Synaptotagmin VIIb. (488 aa)
	atp2b2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1246 aa)
	Prrt2	Uncharacterized protein. (78 aa)
	p2rx3	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (389 aa)
	grik5	Glutamate receptor, ionotropic, kainate 5. (966 aa)
	LOC113588188	Synaptotagmin VIIa. (474 aa)
	LOC113575052	Uncharacterized protein. (516 aa)
	LOC113583936	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (394 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (721 aa)
	atp2b3	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1257 aa)
	LOC113592206	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (953 aa)
	LOC113587287	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
	Fxyd6	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (149 aa)
	LOC113579458	Glutamate receptor, ionotropic, kainate 4. (720 aa)
	LOC113582325	ADAM metallopeptidase domain 23. (709 aa)
	LOC113589437	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1252 aa)
	slc1a2	Amino acid transporter. (549 aa)
	kcnj3	Uncharacterized protein. (495 aa)
	adcy8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
	LOC113579520	Potassium voltage-gated channel, subfamily J, member 19b. (295 aa)
	nptn	Neuroplastin b. (384 aa)
	NCSTN	Ncstrn_small domain-containing protein. (708 aa)
	LOC113582548	Neuroplastin a. (293 aa)
	nectin1	Nectin cell adhesion molecule 1b. (495 aa)
	ENSEEEP00000038398	Proline-rich transmembrane protein 2. (109 aa)
	LOC113583600	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1212 aa)
	LOC113579711	Amino acid transporter. (539 aa)
	LOC113574016	Uncharacterized protein. (538 aa)
	LOC113574056	ADAM metallopeptidase domain 23a. (664 aa)
	LOC113581251	Uncharacterized protein. (713 aa)
	LOC113579739	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1229 aa)
	ENSEEEP00000049996	Zgc:172282. (678 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC113592206	ENSEEEP00000011237	ENSEEEP00000013634	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.900
Fxyd6	LOC113579739	ENSEEEP00000018639	ENSEEEP00000045896	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.413
Fxyd6	LOC113583600	ENSEEEP00000018639	ENSEEEP00000038938	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.413
Fxyd6	LOC113587287	ENSEEEP00000018639	ENSEEEP00000014418	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.413
Fxyd6	LOC113589437	ENSEEEP00000018639	ENSEEEP00000023250	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.413
Fxyd6	atp2b2	ENSEEEP00000018639	ENSEEEP00000004968	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.413
Fxyd6	atp2b3	ENSEEEP00000018639	ENSEEEP00000013452	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.413
LOC113575052	nectin1	ENSEEEP00000008093	ENSEEEP00000038110	Uncharacterized protein.	Nectin cell adhesion molecule 1b.	0.902
LOC113579739	Fxyd6	ENSEEEP00000045896	ENSEEEP00000018639	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.413
LOC113583600	Fxyd6	ENSEEEP00000038938	ENSEEEP00000018639	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.413
LOC113583936	p2rx3	ENSEEEP00000010855	ENSEEEP00000006787	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.780
LOC113587287	Fxyd6	ENSEEEP00000014418	ENSEEEP00000018639	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.413
LOC113589437	Fxyd6	ENSEEEP00000023250	ENSEEEP00000018639	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.413
LOC113592206	CDH2	ENSEEEP00000013634	ENSEEEP00000011237	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.900
atp2b2	Fxyd6	ENSEEEP00000004968	ENSEEEP00000018639	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.413
atp2b3	Fxyd6	ENSEEEP00000013452	ENSEEEP00000018639	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.413
nectin1	LOC113575052	ENSEEEP00000038110	ENSEEEP00000008093	Nectin cell adhesion molecule 1b.	Uncharacterized protein.	0.902
p2rx3	LOC113583936	ENSEEEP00000006787	ENSEEEP00000010855	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.780