(32 nodes) Regulation of synaptic vesicle exocytosis network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gipc2	PDZ domain-containing protein. (328 aa)
	rap1b	Uncharacterized protein. (199 aa)
	LOC113578143	Syntaxin binding protein 5b (tomosyn). (1118 aa)
	snapin	Uncharacterized protein. (129 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (294 aa)
	LOC113580405	Chondroitin sulfate proteoglycan 5b. (396 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2512 aa)
	rap1a	Uncharacterized protein. (185 aa)
	rims4	Regulating synaptic membrane exocytosis 4. (270 aa)
	GRIN3A	Uncharacterized protein. (1117 aa)
	LOC113583936	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (394 aa)
	prepl	Prolyl endopeptidase like. (677 aa)
	cask	Uncharacterized protein; Belongs to the MAGUK family. (920 aa)
	LOC113584057	Amyloid beta (A4) precursor protein-binding, family A, member 2a. (774 aa)
	LOC113583401	Dystrobrevin binding protein 1b. (196 aa)
	LOC113589473	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (569 aa)
	LOC113580770	Syntaxin binding protein 5a (tomosyn). (1052 aa)
	LOC113574444	Chondroitin sulfate proteoglycan 5a. (492 aa)
	LOC113575508	Amyloid beta (A4) precursor protein-binding, family A, member 1b. (905 aa)
	LOC113573310	Uncharacterized protein. (740 aa)
	LOC113591727	GIPC PDZ domain containing family, member 3. (311 aa)
	apba1	Amyloid beta (A4) precursor protein-binding, family A, member 1a. (867 aa)
	LOC113586523	Uncharacterized protein. (197 aa)
	gipc1	PDZ domain-containing protein. (334 aa)
	dtnbp1	Uncharacterized protein. (381 aa)
	fmr1	Uncharacterized protein. (587 aa)
	apba2	Amyloid beta (A4) precursor protein-binding, family A, member 2b. (809 aa)
	LOC113588131	Uncharacterized protein. (621 aa)
	git1	G protein-coupled receptor kinase interacting ArfGAP 1. (758 aa)
	LOC113582582	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (927 aa)
	LOC113588648	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1116 aa)
	LOC113582988	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1117 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRIN3A	LOC113582582	ENSEEEP00000004948	ENSEEEP00000047574	Uncharacterized protein.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.754
GRIN3A	cask	ENSEEEP00000004948	ENSEEEP00000015518	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.754
LOC113575508	LOC113582582	ENSEEEP00000023997	ENSEEEP00000047574	Amyloid beta (A4) precursor protein-binding, family A, member 1b.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.934
LOC113575508	cask	ENSEEEP00000023997	ENSEEEP00000015518	Amyloid beta (A4) precursor protein-binding, family A, member 1b.	Uncharacterized protein; Belongs to the MAGUK family.	0.934
LOC113582582	GRIN3A	ENSEEEP00000047574	ENSEEEP00000004948	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Uncharacterized protein.	0.754
LOC113582582	LOC113575508	ENSEEEP00000047574	ENSEEEP00000023997	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Amyloid beta (A4) precursor protein-binding, family A, member 1b.	0.934
LOC113582582	LOC113584057	ENSEEEP00000047574	ENSEEEP00000017444	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Amyloid beta (A4) precursor protein-binding, family A, member 2a.	0.934
LOC113582582	apba1	ENSEEEP00000047574	ENSEEEP00000026943	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	0.934
LOC113582582	apba2	ENSEEEP00000047574	ENSEEEP00000038979	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Amyloid beta (A4) precursor protein-binding, family A, member 2b.	0.934
LOC113582582	cask	ENSEEEP00000047574	ENSEEEP00000015518	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Uncharacterized protein; Belongs to the MAGUK family.	0.730
LOC113582582	rims4	ENSEEEP00000047574	ENSEEEP00000004790	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	Regulating synaptic membrane exocytosis 4.	0.568
LOC113583401	snapin	ENSEEEP00000018831	ENSEEEP00000001486	Dystrobrevin binding protein 1b.	Uncharacterized protein.	0.971
LOC113583936	LOC113589473	ENSEEEP00000010855	ENSEEEP00000023599	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.704
LOC113584057	LOC113582582	ENSEEEP00000017444	ENSEEEP00000047574	Amyloid beta (A4) precursor protein-binding, family A, member 2a.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.934
LOC113584057	cask	ENSEEEP00000017444	ENSEEEP00000015518	Amyloid beta (A4) precursor protein-binding, family A, member 2a.	Uncharacterized protein; Belongs to the MAGUK family.	0.934
LOC113589473	LOC113583936	ENSEEEP00000023599	ENSEEEP00000010855	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.704
apba1	LOC113582582	ENSEEEP00000026943	ENSEEEP00000047574	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.934
apba1	cask	ENSEEEP00000026943	ENSEEEP00000015518	Amyloid beta (A4) precursor protein-binding, family A, member 1a.	Uncharacterized protein; Belongs to the MAGUK family.	0.934
apba2	LOC113582582	ENSEEEP00000038979	ENSEEEP00000047574	Amyloid beta (A4) precursor protein-binding, family A, member 2b.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.934
apba2	cask	ENSEEEP00000038979	ENSEEEP00000015518	Amyloid beta (A4) precursor protein-binding, family A, member 2b.	Uncharacterized protein; Belongs to the MAGUK family.	0.934