(16 nodes) Regulation of ceramide biosynthetic process network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ccn1	Uncharacterized protein. (365 aa)
	LOC113584190	ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
	LOC113571330	SAM domain-containing protein. (405 aa)
	ormdl1	ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
	LOC113573083	DAGKc domain-containing protein. (233 aa)
	ENSEEEP00000051140	Sphingosine kinase 2. (571 aa)
	SAMD8	SAM domain-containing protein. (410 aa)
	LOC113579409	Uncharacterized protein. (439 aa)
	LOC113568409	Uncharacterized protein. (419 aa)
	ormdl2	ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
	LOC113589963	Deacetylase sirtuin-type domain-containing protein. (441 aa)
	sirt3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (359 aa)
	SPHK1	Sphingosine kinase 1. (364 aa)
	LOC113580757	DAGKc domain-containing protein. (375 aa)
	pla2g6	Phospholipase A2, group VI (cytosolic, calcium-independent). (821 aa)
	LOC113570893	Zgc:153896. (439 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000051140	LOC113573083	ENSEEEP00000051140	ENSEEEP00000051138	Sphingosine kinase 2.	DAGKc domain-containing protein.	0.898
ENSEEEP00000051140	LOC113580757	ENSEEEP00000051140	ENSEEEP00000023183	Sphingosine kinase 2.	DAGKc domain-containing protein.	0.900
LOC113568409	LOC113570893	ENSEEEP00000013369	ENSEEEP00000029997	Uncharacterized protein.	Zgc:153896.	0.903
LOC113568409	LOC113579409	ENSEEEP00000013369	ENSEEEP00000017855	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC113570893	LOC113568409	ENSEEEP00000029997	ENSEEEP00000013369	Zgc:153896.	Uncharacterized protein.	0.903
LOC113570893	LOC113579409	ENSEEEP00000029997	ENSEEEP00000017855	Zgc:153896.	Uncharacterized protein.	0.903
LOC113573083	ENSEEEP00000051140	ENSEEEP00000051138	ENSEEEP00000051140	DAGKc domain-containing protein.	Sphingosine kinase 2.	0.898
LOC113579409	LOC113568409	ENSEEEP00000017855	ENSEEEP00000013369	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC113579409	LOC113570893	ENSEEEP00000017855	ENSEEEP00000029997	Uncharacterized protein.	Zgc:153896.	0.903
LOC113580757	ENSEEEP00000051140	ENSEEEP00000023183	ENSEEEP00000051140	DAGKc domain-containing protein.	Sphingosine kinase 2.	0.900