(61 nodes) Ruffle network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113572350	SAM pointed domain containing ETS transcription factor. (328 aa)
	LOC113589864	SH3 domain-containing protein. (474 aa)
	ENSEEEP00000000439	Uncharacterized protein. (150 aa)
	LOC113586553	Myosin VIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1262 aa)
	kank1	ANK_REP_REGION domain-containing protein. (1318 aa)
	eps8l2	EPS8 like 2. (627 aa)
	kank3	KN motif and ankyrin repeat domains 3. (899 aa)
	LOC113581618	Inositol polyphosphate-5-phosphatase Jb. (453 aa)
	ENSEEEP00000009679	SEC7 domain-containing protein. (187 aa)
	ENSEEEP00000009729	Pleckstrin and Sec7 domain containing a. (314 aa)
	LOC113583907	Family with sequence similarity 107 member A. (285 aa)
	LOC113573706	EF-hand domain-containing protein. (148 aa)
	LOC113571634	Uncharacterized protein. (438 aa)
	SPDEF	Uncharacterized protein. (362 aa)
	ENSEEEP00000015501	Uncharacterized protein. (1526 aa)
	ENSEEEP00000016039	SEC7 domain-containing protein. (119 aa)
	ENSEEEP00000016089	LIM zinc-binding domain-containing protein. (81 aa)
	LOC113584952	Rho/rac guanine nucleotide exchange factor (GEF) 2. (831 aa)
	ENSEEEP00000017428	CUB domain-containing protein. (104 aa)
	plek	Pleckstrin. (353 aa)
	itgb1	Integrin beta; Belongs to the integrin beta chain family. (807 aa)
	LOC113572333	Uncharacterized protein. (441 aa)
	LOC113568006	Integrin beta; Belongs to the integrin beta chain family. (807 aa)
	LOC113568009	F-BAR domain-containing protein. (323 aa)
	als2	Amyotrophic lateral sclerosis 2b (juvenile). (1563 aa)
	ENSEEEP00000023378	LIM zinc-binding domain-containing protein. (76 aa)
	LOC113587403	Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1245 aa)
	eps8	Epidermal growth factor receptor pathway substrate 8a. (723 aa)
	itgb7	Integrin beta; Belongs to the integrin beta chain family. (676 aa)
	LOC113573409	Pleckstrin and Sec7 domain containing 2. (761 aa)
	ENSEEEP00000031422	KN motif and ankyrin repeat domains 1b. (1155 aa)
	LIMA1	LIM zinc-binding domain-containing protein. (710 aa)
	c2cd5	C2 calcium-dependent domain containing 5. (1064 aa)
	clasp2	Cytoplasmic linker associated protein 2. (1289 aa)
	Sh3yl1	SH3 and SYLF domain containing 1. (158 aa)
	LOC113581159	Nucleoside diphosphate kinase. (153 aa)
	ENSEEEP00000036431	Inositol polyphosphate-5-phosphatase Kb. (454 aa)
	ENSEEEP00000036876	Sprouty RTK signaling antagonist 2. (281 aa)
	arhgef2	Rho guanine nucleotide exchange factor (GEF) 1a. (897 aa)
	SPRY3	Uncharacterized protein. (282 aa)
	pacsin3	Protein kinase C and casein kinase substrate in neurons 3. (476 aa)
	LOC113575200	NME/NM23 nucleoside diphosphate kinase 4; Belongs to the NDK family. (199 aa)
	ENSEEEP00000039179	LIM zinc-binding domain-containing protein. (194 aa)
	ddx58	Uncharacterized protein. (943 aa)
	ENSEEEP00000039760	PH domain-containing protein. (264 aa)
	ENSEEEP00000039763	SEC7 domain-containing protein. (107 aa)
	LOC113578531	Amyotrophic lateral sclerosis 2a (juvenile). (1653 aa)
	ENSEEEP00000040277	PH domain-containing protein. (302 aa)
	LOC113588091	Uncharacterized protein. (1056 aa)
	LOC113586407	Inositol polyphosphate-5-phosphatase Ka. (480 aa)
	LOC113570399	LIM zinc-binding domain-containing protein. (636 aa)
	arfgap3	Arf-GAP domain-containing protein. (513 aa)
	LOC113573546	Uncharacterized protein. (483 aa)
	LOC113576746	Pleckstrin and Sec7 domain containing 3, like. (501 aa)
	plekha1	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (367 aa)
	LOC113590905	Uncharacterized protein. (390 aa)
	plek2	Uncharacterized protein. (358 aa)
	ENSEEEP00000049206	Uncharacterized protein. (873 aa)
	mkln1	Uncharacterized protein. (731 aa)
	nme6	NDK domain-containing protein; Belongs to the NDK family. (182 aa)
	ENSEEEP00000051674	Inositol polyphosphate-5-phosphatase Ja. (436 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000009679	ENSEEEP00000009729	ENSEEEP00000009679	ENSEEEP00000009729	SEC7 domain-containing protein.	Pleckstrin and Sec7 domain containing a.	0.894
ENSEEEP00000009729	ENSEEEP00000009679	ENSEEEP00000009729	ENSEEEP00000009679	Pleckstrin and Sec7 domain containing a.	SEC7 domain-containing protein.	0.894
ENSEEEP00000009729	ENSEEEP00000016039	ENSEEEP00000009729	ENSEEEP00000016039	Pleckstrin and Sec7 domain containing a.	SEC7 domain-containing protein.	0.899
ENSEEEP00000016039	ENSEEEP00000009729	ENSEEEP00000016039	ENSEEEP00000009729	SEC7 domain-containing protein.	Pleckstrin and Sec7 domain containing a.	0.899
LOC113575200	LOC113581159	ENSEEEP00000038866	ENSEEEP00000034949	NME/NM23 nucleoside diphosphate kinase 4; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.932
LOC113575200	nme6	ENSEEEP00000038866	ENSEEEP00000051002	NME/NM23 nucleoside diphosphate kinase 4; Belongs to the NDK family.	NDK domain-containing protein; Belongs to the NDK family.	0.934
LOC113581159	LOC113575200	ENSEEEP00000034949	ENSEEEP00000038866	Nucleoside diphosphate kinase.	NME/NM23 nucleoside diphosphate kinase 4; Belongs to the NDK family.	0.932
LOC113581159	nme6	ENSEEEP00000034949	ENSEEEP00000051002	Nucleoside diphosphate kinase.	NDK domain-containing protein; Belongs to the NDK family.	0.920
nme6	LOC113575200	ENSEEEP00000051002	ENSEEEP00000038866	NDK domain-containing protein; Belongs to the NDK family.	NME/NM23 nucleoside diphosphate kinase 4; Belongs to the NDK family.	0.934
nme6	LOC113581159	ENSEEEP00000051002	ENSEEEP00000034949	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.920