(7 nodes) HOPS complex network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vps18	Pep3_Vps18 domain-containing protein. (977 aa)
	LOC113567542	CNH domain-containing protein. (188 aa)
	vps41	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (857 aa)
	WDR88	WD repeat domain 88. (389 aa)
	vps39	VPS39 subunit of HOPS complex. (726 aa)
	vps8	Vacuolar protein sorting 8 homolog (S. cerevisiae). (1398 aa)
	vps11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (927 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC113567542	vps11	ENSEEEP00000035519	ENSEEEP00000031819	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.960
LOC113567542	vps18	ENSEEEP00000035519	ENSEEEP00000027628	CNH domain-containing protein.	Pep3_Vps18 domain-containing protein.	0.958
LOC113567542	vps39	ENSEEEP00000035519	ENSEEEP00000008579	CNH domain-containing protein.	VPS39 subunit of HOPS complex.	0.935
LOC113567542	vps41	ENSEEEP00000035519	ENSEEEP00000015188	CNH domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.957
LOC113567542	vps8	ENSEEEP00000035519	ENSEEEP00000019165	CNH domain-containing protein.	Vacuolar protein sorting 8 homolog (S. cerevisiae).	0.872
vps11	LOC113567542	ENSEEEP00000031819	ENSEEEP00000035519	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	CNH domain-containing protein.	0.960
vps11	vps18	ENSEEEP00000031819	ENSEEEP00000027628	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Pep3_Vps18 domain-containing protein.	0.999
vps11	vps39	ENSEEEP00000031819	ENSEEEP00000008579	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	VPS39 subunit of HOPS complex.	0.995
vps11	vps41	ENSEEEP00000031819	ENSEEEP00000015188	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.999
vps11	vps8	ENSEEEP00000031819	ENSEEEP00000019165	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	Vacuolar protein sorting 8 homolog (S. cerevisiae).	0.993
vps18	LOC113567542	ENSEEEP00000027628	ENSEEEP00000035519	Pep3_Vps18 domain-containing protein.	CNH domain-containing protein.	0.958
vps18	vps11	ENSEEEP00000027628	ENSEEEP00000031819	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.999
vps18	vps39	ENSEEEP00000027628	ENSEEEP00000008579	Pep3_Vps18 domain-containing protein.	VPS39 subunit of HOPS complex.	0.995
vps18	vps41	ENSEEEP00000027628	ENSEEEP00000015188	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.999
vps18	vps8	ENSEEEP00000027628	ENSEEEP00000019165	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting 8 homolog (S. cerevisiae).	0.993
vps39	LOC113567542	ENSEEEP00000008579	ENSEEEP00000035519	VPS39 subunit of HOPS complex.	CNH domain-containing protein.	0.935
vps39	vps11	ENSEEEP00000008579	ENSEEEP00000031819	VPS39 subunit of HOPS complex.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.995
vps39	vps18	ENSEEEP00000008579	ENSEEEP00000027628	VPS39 subunit of HOPS complex.	Pep3_Vps18 domain-containing protein.	0.995
vps39	vps41	ENSEEEP00000008579	ENSEEEP00000015188	VPS39 subunit of HOPS complex.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.995
vps39	vps8	ENSEEEP00000008579	ENSEEEP00000019165	VPS39 subunit of HOPS complex.	Vacuolar protein sorting 8 homolog (S. cerevisiae).	0.872