3 items (Electrophorus electricus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fbxw8	Uncharacterized protein. (653 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (135 aa)
	skp1	Uncharacterized protein; Belongs to the SKP1 family. (163 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
fbxw8	rbx1	ENSEEEP00000019612	ENSEEEP00000049513	Uncharacterized protein.	Ring-box 1, E3 ubiquitin protein ligase.	0.964
fbxw8	skp1	ENSEEEP00000019612	ENSEEEP00000047043	Uncharacterized protein.	Uncharacterized protein; Belongs to the SKP1 family.	0.980
rbx1	fbxw8	ENSEEEP00000049513	ENSEEEP00000019612	Ring-box 1, E3 ubiquitin protein ligase.	Uncharacterized protein.	0.964
rbx1	skp1	ENSEEEP00000049513	ENSEEEP00000047043	Ring-box 1, E3 ubiquitin protein ligase.	Uncharacterized protein; Belongs to the SKP1 family.	0.999
skp1	fbxw8	ENSEEEP00000047043	ENSEEEP00000019612	Uncharacterized protein; Belongs to the SKP1 family.	Uncharacterized protein.	0.980
skp1	rbx1	ENSEEEP00000047043	ENSEEEP00000049513	Uncharacterized protein; Belongs to the SKP1 family.	Ring-box 1, E3 ubiquitin protein ligase.	0.999