(22 nodes) Melanosome membrane network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAB38	Uncharacterized protein. (210 aa)
	tyr	Uncharacterized protein. (538 aa)
	abcb6	ATP-binding cassette, sub-family B (MDR/TAP), member 6a. (846 aa)
	LOC113578282	Uncharacterized protein. (213 aa)
	tyrp1	Tyrosinase-related protein 1a. (542 aa)
	LOC113580533	Si:dkey-30c15.2. (312 aa)
	LOC113574500	Uncharacterized protein. (212 aa)
	ENSEEEP00000016852	Tyrosinase-related protein 1b. (543 aa)
	rab32	Uncharacterized protein. (209 aa)
	ENSEEEP00000025113	RAB38b, member of RAS oncogene family. (231 aa)
	SLC45A4	Solute carrier family 45 member 4. (684 aa)
	TYR	Tyrosinase. (540 aa)
	slc45a2	Uncharacterized protein. (553 aa)
	ENSEEEP00000032594	Uncharacterized protein. (610 aa)
	dtnbp1	Uncharacterized protein. (381 aa)
	abcc10	Uncharacterized protein. (1549 aa)
	LOC113571189	Uncharacterized protein. (762 aa)
	gpr143	G protein-coupled receptor 143. (398 aa)
	oca2	Oculocutaneous albinism II. (810 aa)
	dct	Dopachrome tautomerase. (528 aa)
	Slc45a1	Uncharacterized protein. (140 aa)
	mreg	Zgc:91968. (206 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000016852	gpr143	ENSEEEP00000016852	ENSEEEP00000038843	Tyrosinase-related protein 1b.	G protein-coupled receptor 143.	0.412
ENSEEEP00000016852	oca2	ENSEEEP00000016852	ENSEEEP00000039011	Tyrosinase-related protein 1b.	Oculocutaneous albinism II.	0.546
LOC113580533	oca2	ENSEEEP00000014244	ENSEEEP00000039011	Si:dkey-30c15.2.	Oculocutaneous albinism II.	0.457
Slc45a1	gpr143	ENSEEEP00000049793	ENSEEEP00000038843	Uncharacterized protein.	G protein-coupled receptor 143.	0.421
Slc45a1	oca2	ENSEEEP00000049793	ENSEEEP00000039011	Uncharacterized protein.	Oculocutaneous albinism II.	0.505
Slc45a1	tyr	ENSEEEP00000049793	ENSEEEP00000002289	Uncharacterized protein.	Uncharacterized protein.	0.458
TYR	oca2	ENSEEEP00000025273	ENSEEEP00000039011	Tyrosinase.	Oculocutaneous albinism II.	0.513
TYR	tyr	ENSEEEP00000025273	ENSEEEP00000002289	Tyrosinase.	Uncharacterized protein.	0.901
abcb6	abcc10	ENSEEEP00000006424	ENSEEEP00000036030	ATP-binding cassette, sub-family B (MDR/TAP), member 6a.	Uncharacterized protein.	0.447
abcc10	abcb6	ENSEEEP00000036030	ENSEEEP00000006424	Uncharacterized protein.	ATP-binding cassette, sub-family B (MDR/TAP), member 6a.	0.447
dct	oca2	ENSEEEP00000041900	ENSEEEP00000039011	Dopachrome tautomerase.	Oculocutaneous albinism II.	0.433
gpr143	ENSEEEP00000016852	ENSEEEP00000038843	ENSEEEP00000016852	G protein-coupled receptor 143.	Tyrosinase-related protein 1b.	0.412
gpr143	Slc45a1	ENSEEEP00000038843	ENSEEEP00000049793	G protein-coupled receptor 143.	Uncharacterized protein.	0.421
gpr143	oca2	ENSEEEP00000038843	ENSEEEP00000039011	G protein-coupled receptor 143.	Oculocutaneous albinism II.	0.592
gpr143	slc45a2	ENSEEEP00000038843	ENSEEEP00000030263	G protein-coupled receptor 143.	Uncharacterized protein.	0.421
gpr143	tyr	ENSEEEP00000038843	ENSEEEP00000002289	G protein-coupled receptor 143.	Uncharacterized protein.	0.408
gpr143	tyrp1	ENSEEEP00000038843	ENSEEEP00000014049	G protein-coupled receptor 143.	Tyrosinase-related protein 1a.	0.412
oca2	ENSEEEP00000016852	ENSEEEP00000039011	ENSEEEP00000016852	Oculocutaneous albinism II.	Tyrosinase-related protein 1b.	0.546
oca2	LOC113580533	ENSEEEP00000039011	ENSEEEP00000014244	Oculocutaneous albinism II.	Si:dkey-30c15.2.	0.457
oca2	Slc45a1	ENSEEEP00000039011	ENSEEEP00000049793	Oculocutaneous albinism II.	Uncharacterized protein.	0.505