(92 nodes) Calponin homology domain network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113572840	Plectin b. (4662 aa)
	LOC113588662	Rho guanine nucleotide exchange factor (GEF) 7a. (842 aa)
	ENSEEEP00000050727	Calponin-homology (CH) domain-containing protein. (141 aa)
	hook2	Hook microtubule-tethering protein 2. (700 aa)
	Nav2	Calponin-homology (CH) domain-containing protein. (559 aa)
	ENSEEEP00000051673	Smoothelin a. (261 aa)
	LOC113583030	Transgelin; Belongs to the calponin family. (270 aa)
	LOC113576381	Uncharacterized protein. (258 aa)
	arhgef6	Uncharacterized protein. (782 aa)
	LOC113586986	Calponin-homology (CH) domain-containing protein. (213 aa)
	smtnl2	Smoothelin, like. (460 aa)
	LOC113585178	Actinin alpha 3b. (931 aa)
	iqgap3	IQ motif containing GTPase activating protein 3. (1642 aa)
	ENSEEEP00000031097	Calponin-homology (CH) domain-containing protein. (120 aa)
	VAV1	Uncharacterized protein. (844 aa)
	LOC113573881	Transgelin; Belongs to the calponin family. (199 aa)
	ENSEEEP00000028619	Microtubule associated monooxygenase, calponin and LIM domain containing 2b. (1385 aa)
	LOC113582479	Uncharacterized protein. (401 aa)
	ENSEEEP00000028444	Uncharacterized protein. (734 aa)
	hook1	Hook microtubule-tethering protein 1. (718 aa)
	FLNB	Filamin B. (2615 aa)
	LOC113570119	Uncharacterized protein. (641 aa)
	ENSEEEP00000027352	Calponin-homology (CH) domain-containing protein. (166 aa)
	Sptbn4	Uncharacterized protein. (562 aa)
	sptbn1	Spectrin beta chain; Belongs to the spectrin family. (2309 aa)
	gas2l1	Growth arrest specific 2 like 1. (386 aa)
	ENSEEEP00000026190	Calponin-homology (CH) domain-containing protein. (101 aa)
	micall1	MICAL-like 1a. (879 aa)
	cnn3	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa)
	ENSEEEP00000022902	Leucine-rich repeats and calponin homology (CH) domain containing 1. (519 aa)
	mapre2	Uncharacterized protein. (331 aa)
	LOC113575791	Uncharacterized protein. (610 aa)
	ENSEEEP00000019996	Calponin-homology (CH) domain-containing protein. (114 aa)
	DST	Dystonin. (6959 aa)
	ENSEEEP00000016847	Uncharacterized protein. (1065 aa)
	LOC113567972	Uncharacterized protein. (550 aa)
	ENSEEEP00000016720	Calponin 1, basic, smooth muscle, a. (282 aa)
	pls3	Plastin 3 (T isoform). (644 aa)
	ENSEEEP00000016065	LIM and calponin homology domains 1a. (873 aa)
	LOC113591548	Uncharacterized protein. (757 aa)
	LOC113575485	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1423 aa)
	specc1	Calponin-homology (CH) domain-containing protein. (955 aa)
	iqgap2	Uncharacterized protein. (1663 aa)
	lcp1	Uncharacterized protein. (638 aa)
	spata4	Spermatogenesis associated 4. (307 aa)
	LOC113583288	Uncharacterized protein. (4626 aa)
	Lmo7	Calponin-homology (CH) domain-containing protein. (152 aa)
	Vav3	Calponin-homology (CH) domain-containing protein. (96 aa)
	ehbp1	EH domain binding protein 1. (1068 aa)
	LOC113581603	Calponin-homology (CH) domain-containing protein. (473 aa)
	LOC113574674	Uncharacterized protein. (960 aa)
	gas2l2	Growth arrest specific 2 like 2. (321 aa)
	camsap2	Calmodulin regulated spectrin-associated protein family, member 2a. (1414 aa)
	vav2	Uncharacterized protein. (878 aa)
	LOC113582131	Calponin-homology (CH) domain-containing protein. (1384 aa)
	parvg	Parvin, gamma. (299 aa)
	LOC113589922	Uncharacterized protein. (365 aa)
	LOC113578866	Spectrin beta chain; Belongs to the spectrin family. (2289 aa)
	UTRN	Utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane. (2896 aa)
	ENSEEEP00000006250	Growth arrest-specific 2b. (331 aa)
	spef1	Calponin-homology (CH) domain-containing protein. (231 aa)
	sptbn5	Spectrin, beta, non-erythrocytic 5. (3015 aa)
	LOC113586551	Uncharacterized protein. (273 aa)
	LOC113586020	Uncharacterized protein. (920 aa)
	gas2	Growth arrest-specific 2a. (321 aa)
	LOC113588770	Filamin C, gamma a (actin binding protein 280). (2619 aa)
	lrch3	Leucine-rich repeats and calponin homology (CH) domain containing 3. (735 aa)
	Syne1	Uncharacterized protein. (1355 aa)
	Micall2	Calponin-homology (CH) domain-containing protein. (94 aa)
	clmn	Calmin. (1129 aa)
	ENSEEEP00000033667	Calponin-homology (CH) domain-containing protein. (98 aa)
	LOC113579116	DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1454 aa)
	LOC113579076	Uncharacterized protein. (296 aa)
	parva	Parvin, alpha b. (392 aa)
	ENSEEEP00000034272	Calponin-homology (CH) domain-containing protein. (101 aa)
	MACF1	Microtubule actin crosslinking factor 1. (7019 aa)
	LOC113572472	Calponin-homology (CH) domain-containing protein. (466 aa)
	LOC113589928	Actinin, alpha 4. (896 aa)
	LOC113588745	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (335 aa)
	LOC113575727	IQ motif containing GTPase activating protein 1. (802 aa)
	tagln	Transgelin; Belongs to the calponin family. (199 aa)
	cnn1	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
	LOC113580354	Uncharacterized protein. (844 aa)
	LOC113573478	Leucine-rich repeats and calponin homology (CH) domain containing 4. (691 aa)
	LOC113581816	Uncharacterized protein. (2809 aa)
	LOC113588057	Calponin-homology (CH) domain-containing protein. (339 aa)
	mapre3	Uncharacterized protein. (263 aa)
	LOC113582685	Uncharacterized protein. (2584 aa)
	LOC113577980	Growth arrest-specific 2 like 3. (620 aa)
	LOC113574145	Spectrin beta chain; Belongs to the spectrin family. (2436 aa)
	HOOK3	Hook microtubule tethering protein 3. (736 aa)
	camsap1	Calmodulin regulated spectrin-associated protein 1b. (1523 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000016720	LOC113570119	ENSEEEP00000016720	ENSEEEP00000027375	Calponin 1, basic, smooth muscle, a.	Uncharacterized protein.	0.452
ENSEEEP00000016720	lcp1	ENSEEEP00000016720	ENSEEEP00000013027	Calponin 1, basic, smooth muscle, a.	Uncharacterized protein.	0.452
ENSEEEP00000016720	pls3	ENSEEEP00000016720	ENSEEEP00000016562	Calponin 1, basic, smooth muscle, a.	Plastin 3 (T isoform).	0.452
ENSEEEP00000027352	LOC113574674	ENSEEEP00000027352	ENSEEEP00000008805	Calponin-homology (CH) domain-containing protein.	Uncharacterized protein.	0.905
ENSEEEP00000027352	Lmo7	ENSEEEP00000027352	ENSEEEP00000011171	Calponin-homology (CH) domain-containing protein.	Calponin-homology (CH) domain-containing protein.	0.901
FLNB	LOC113582685	ENSEEEP00000027641	ENSEEEP00000044655	Filamin B.	Uncharacterized protein.	0.901
FLNB	LOC113583030	ENSEEEP00000027641	ENSEEEP00000051736	Filamin B.	Transgelin; Belongs to the calponin family.	0.438
FLNB	LOC113586986	ENSEEEP00000027641	ENSEEEP00000032518	Filamin B.	Calponin-homology (CH) domain-containing protein.	0.438
FLNB	LOC113588770	ENSEEEP00000027641	ENSEEEP00000003174	Filamin B.	Filamin C, gamma a (actin binding protein 280).	0.901
FLNB	tagln	ENSEEEP00000027641	ENSEEEP00000037335	Filamin B.	Transgelin; Belongs to the calponin family.	0.438
HOOK3	hook2	ENSEEEP00000047310	ENSEEEP00000050793	Hook microtubule tethering protein 3.	Hook microtubule-tethering protein 2.	0.513
LOC113567972	LOC113582479	ENSEEEP00000016843	ENSEEEP00000028549	Uncharacterized protein.	Uncharacterized protein.	0.492
LOC113567972	LOC113589922	ENSEEEP00000016843	ENSEEEP00000006938	Uncharacterized protein.	Uncharacterized protein.	0.492
LOC113567972	parva	ENSEEEP00000016843	ENSEEEP00000034269	Uncharacterized protein.	Parvin, alpha b.	0.492
LOC113570119	ENSEEEP00000016720	ENSEEEP00000027375	ENSEEEP00000016720	Uncharacterized protein.	Calponin 1, basic, smooth muscle, a.	0.452
LOC113570119	LOC113573881	ENSEEEP00000027375	ENSEEEP00000028680	Uncharacterized protein.	Transgelin; Belongs to the calponin family.	0.452
LOC113570119	LOC113583030	ENSEEEP00000027375	ENSEEEP00000051736	Uncharacterized protein.	Transgelin; Belongs to the calponin family.	0.485
LOC113570119	LOC113586986	ENSEEEP00000027375	ENSEEEP00000032518	Uncharacterized protein.	Calponin-homology (CH) domain-containing protein.	0.485
LOC113570119	LOC113588745	ENSEEEP00000027375	ENSEEEP00000037177	Uncharacterized protein.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.452
LOC113570119	cnn1	ENSEEEP00000027375	ENSEEEP00000039013	Uncharacterized protein.	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	0.452