(12 nodes) MAD homology, MH1 network (Electrophorus electricus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113571196	Mothers against decapentaplegic homolog. (572 aa)
	ENSEEEP00000001488	Mothers against decapentaplegic homolog. (440 aa)
	smad7	Mothers against decapentaplegic homolog. (376 aa)
	smad9	Mothers against decapentaplegic homolog. (466 aa)
	LOC113567946	Mothers against decapentaplegic homolog. (524 aa)
	smad6	Mothers against decapentaplegic homolog. (490 aa)
	LOC113585069	Mothers against decapentaplegic homolog. (447 aa)
	smad4	Mothers against decapentaplegic homolog. (545 aa)
	smad5	Uncharacterized protein. (464 aa)
	smad2	Mothers against decapentaplegic homolog. (468 aa)
	LOC113574086	Mothers against decapentaplegic homolog. (425 aa)
	LOC113574093	Mothers against decapentaplegic homolog. (464 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSEEEP00000001488	LOC113574086	ENSEEEP00000001488	ENSEEEP00000042768	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.784
ENSEEEP00000001488	LOC113574093	ENSEEEP00000001488	ENSEEEP00000042775	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.450
ENSEEEP00000001488	LOC113585069	ENSEEEP00000001488	ENSEEEP00000019850	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.784
ENSEEEP00000001488	smad2	ENSEEEP00000001488	ENSEEEP00000039970	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.784
ENSEEEP00000001488	smad5	ENSEEEP00000001488	ENSEEEP00000030638	Mothers against decapentaplegic homolog.	Uncharacterized protein.	0.692
ENSEEEP00000001488	smad6	ENSEEEP00000001488	ENSEEEP00000019555	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.450
ENSEEEP00000001488	smad7	ENSEEEP00000001488	ENSEEEP00000006576	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.450
ENSEEEP00000001488	smad9	ENSEEEP00000001488	ENSEEEP00000012380	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.692
LOC113567946	LOC113574086	ENSEEEP00000016285	ENSEEEP00000042768	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.786
LOC113567946	LOC113574093	ENSEEEP00000016285	ENSEEEP00000042775	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.450
LOC113567946	LOC113585069	ENSEEEP00000016285	ENSEEEP00000019850	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.786
LOC113567946	smad2	ENSEEEP00000016285	ENSEEEP00000039970	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.784
LOC113567946	smad5	ENSEEEP00000016285	ENSEEEP00000030638	Mothers against decapentaplegic homolog.	Uncharacterized protein.	0.761
LOC113567946	smad6	ENSEEEP00000016285	ENSEEEP00000019555	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.450
LOC113567946	smad7	ENSEEEP00000016285	ENSEEEP00000006576	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.450
LOC113567946	smad9	ENSEEEP00000016285	ENSEEEP00000012380	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.764
LOC113571196	LOC113574086	ENSEEEP00000032266	ENSEEEP00000042768	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.977
LOC113571196	LOC113574093	ENSEEEP00000032266	ENSEEEP00000042775	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.450
LOC113571196	LOC113585069	ENSEEEP00000032266	ENSEEEP00000019850	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.784
LOC113571196	smad2	ENSEEEP00000032266	ENSEEEP00000039970	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.977