(37 nodes) Ribosomal protein S5 domain 2-type fold network (Electrophorus electricus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	mrps5	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (371 aa)
	exosc7	Uncharacterized protein. (291 aa)
	rps2	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (283 aa)
	galk1	Uncharacterized protein. (394 aa)
	exosc8	Uncharacterized protein. (281 aa)
	gfm2	Tr-type G domain-containing protein. (762 aa)
	exosc9	Uncharacterized protein. (388 aa)
	mlh1	DNA_mis_repair domain-containing protein. (724 aa)
	pms2	PMS1 homolog 2, mismatch repair system component. (832 aa)
	exosc4	Uncharacterized protein. (245 aa)
	LOC113569531	HATPase_c domain-containing protein. (752 aa)
	lonp1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (980 aa)
	LOC113569657	HATPase_c domain-containing protein. (723 aa)
	PNPT1	S1 motif domain-containing protein. (769 aa)
	gfm1	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (886 aa)
	hsp90ab1	HATPase_c domain-containing protein. (749 aa)
	rps16	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	exosc5	Uncharacterized protein. (218 aa)
	lonp2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (843 aa)
	LOC113579471	Uncharacterized protein. (114 aa)
	eftud2	Tr-type G domain-containing protein. (971 aa)
	galk2	Uncharacterized protein. (459 aa)
	efl1	Elongation factor like GTPase 1. (1125 aa)
	exosc6	RNase_PH domain-containing protein. (271 aa)
	mvd	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (402 aa)
	LOC113579594	Uncharacterized protein. (629 aa)
	impact	Impact RWD domain protein. (285 aa)
	mrps9	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (380 aa)
	hsp90b1	HATPase_c domain-containing protein. (811 aa)
	mlh3	Uncharacterized protein. (1098 aa)
	LOC113582703	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1597 aa)
	fcsk	Fucokinase. (1041 aa)
	trap1	HATPase_c domain-containing protein. (716 aa)
	top2b	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1600 aa)
	LOC113589231	Tr-type G domain-containing protein. (871 aa)
	LOC113576208	Tr-type G domain-containing protein. (865 aa)
	pms1	HMG box domain-containing protein. (915 aa)

Your Current Organism:

Electrophorus electricus

NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC113569531	LOC113569657	ENSEEEP00000023929	ENSEEEP00000025037	HATPase_c domain-containing protein.	HATPase_c domain-containing protein.	0.900
LOC113569531	LOC113576208	ENSEEEP00000023929	ENSEEEP00000048604	HATPase_c domain-containing protein.	Tr-type G domain-containing protein.	0.509
LOC113569531	LOC113589231	ENSEEEP00000023929	ENSEEEP00000048369	HATPase_c domain-containing protein.	Tr-type G domain-containing protein.	0.509
LOC113569531	hsp90ab1	ENSEEEP00000023929	ENSEEEP00000027923	HATPase_c domain-containing protein.	HATPase_c domain-containing protein.	0.934
LOC113569531	lonp1	ENSEEEP00000023929	ENSEEEP00000025034	HATPase_c domain-containing protein.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.549
LOC113569531	lonp2	ENSEEEP00000023929	ENSEEEP00000030579	HATPase_c domain-containing protein.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.549
LOC113569657	LOC113569531	ENSEEEP00000025037	ENSEEEP00000023929	HATPase_c domain-containing protein.	HATPase_c domain-containing protein.	0.900
LOC113569657	LOC113576208	ENSEEEP00000025037	ENSEEEP00000048604	HATPase_c domain-containing protein.	Tr-type G domain-containing protein.	0.509
LOC113569657	LOC113589231	ENSEEEP00000025037	ENSEEEP00000048369	HATPase_c domain-containing protein.	Tr-type G domain-containing protein.	0.509
LOC113569657	hsp90ab1	ENSEEEP00000025037	ENSEEEP00000027923	HATPase_c domain-containing protein.	HATPase_c domain-containing protein.	0.935
LOC113569657	lonp1	ENSEEEP00000025037	ENSEEEP00000025034	HATPase_c domain-containing protein.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.549
LOC113569657	lonp2	ENSEEEP00000025037	ENSEEEP00000030579	HATPase_c domain-containing protein.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.549
LOC113576208	LOC113569531	ENSEEEP00000048604	ENSEEEP00000023929	Tr-type G domain-containing protein.	HATPase_c domain-containing protein.	0.509
LOC113576208	LOC113569657	ENSEEEP00000048604	ENSEEEP00000025037	Tr-type G domain-containing protein.	HATPase_c domain-containing protein.	0.509
LOC113576208	LOC113582703	ENSEEEP00000048604	ENSEEEP00000044755	Tr-type G domain-containing protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.463
LOC113576208	PNPT1	ENSEEEP00000048604	ENSEEEP00000025438	Tr-type G domain-containing protein.	S1 motif domain-containing protein.	0.683
LOC113576208	hsp90ab1	ENSEEEP00000048604	ENSEEEP00000027923	Tr-type G domain-containing protein.	HATPase_c domain-containing protein.	0.509
LOC113576208	hsp90b1	ENSEEEP00000048604	ENSEEEP00000041052	Tr-type G domain-containing protein.	HATPase_c domain-containing protein.	0.439
LOC113576208	mrps5	ENSEEEP00000048604	ENSEEEP00000003123	Tr-type G domain-containing protein.	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.865
LOC113576208	mrps9	ENSEEEP00000048604	ENSEEEP00000039185	Tr-type G domain-containing protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.938