STRINGSTRING
cdkn1a cdkn1a ENSEEEP00000050839 ENSEEEP00000050839 ENSEEEP00000049401 ENSEEEP00000049401 ccne2 ccne2 CCNE2 CCNE2 LOC113583701 LOC113583701 LOC113573558 LOC113573558 ENSEEEP00000043857 ENSEEEP00000043857 LOC113577352 LOC113577352 H2AZ1 H2AZ1 LOC113579698 LOC113579698 LOC113569449 LOC113569449 ENSEEEP00000039231 ENSEEEP00000039231 ENSEEEP00000037429 ENSEEEP00000037429 LOC113583571 LOC113583571 LOC113587549 LOC113587549 ENSEEEP00000036356 ENSEEEP00000036356 ENSEEEP00000034928 ENSEEEP00000034928 tp53 tp53 ccna2 ccna2 ENSEEEP00000032310 ENSEEEP00000032310 LOC113587865 LOC113587865 LOC113570214 LOC113570214 LOC113579037 LOC113579037 ENSEEEP00000029755 ENSEEEP00000029755 LOC113586889 LOC113586889 Ubn1 Ubn1 ccne1 ccne1 mre11 mre11 LOC113576955 LOC113576955 ENSEEEP00000023877 ENSEEEP00000023877 LOC113585605 LOC113585605 pot1 pot1 cdk2 cdk2 LOC113571645 LOC113571645 LOC113567926 LOC113567926 rad50 rad50 LOC113568370 LOC113568370 ENSEEEP00000012861 ENSEEEP00000012861 ccna1 ccna1 LOC113578292 LOC113578292 nbn nbn ENSEEEP00000007003 ENSEEEP00000007003 ENSEEEP00000005940 ENSEEEP00000005940 LOC113569058 LOC113569058 LOC113569037 LOC113569037 HIST1H2BF HIST1H2BF LOC113568938 LOC113568938 ENSEEEP00000005177 ENSEEEP00000005177 LOC113568893 LOC113568893 LOC113568892 LOC113568892 LOC113583786 LOC113583786 LOC113572522 LOC113572522 ENSEEEP00000001285 ENSEEEP00000001285 ENSEEEP00000000760 ENSEEEP00000000760 LOC113573654 LOC113573654 LOC113569455 LOC113569455 ENSEEEP00000000649 ENSEEEP00000000649 ENSEEEP00000000319 ENSEEEP00000000319
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdkn1aUncharacterized protein. (166 aa)
ENSEEEP00000050839Metallophos domain-containing protein. (106 aa)
ENSEEEP00000049401Histone H2B; Belongs to the histone H2B family. (134 aa)
ccne2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (394 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (320 aa)
LOC113583701Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC113573558Uncharacterized protein. (174 aa)
ENSEEEP00000043857Telomeric repeat binding factor a. (471 aa)
LOC113577352Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (366 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (134 aa)
LOC113579698Uncharacterized protein. (217 aa)
LOC113569449Histone H4. (103 aa)
ENSEEEP00000039231Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
ENSEEEP00000037429Uncharacterized protein. (115 aa)
LOC113583571Uncharacterized protein. (191 aa)
LOC113587549Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (995 aa)
ENSEEEP00000036356Histone H2A; Belongs to the histone H2A family. (158 aa)
ENSEEEP00000034928Uncharacterized protein. (435 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (370 aa)
ccna2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (428 aa)
ENSEEEP00000032310ATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3024 aa)
LOC113587865Uncharacterized protein. (195 aa)
LOC113570214Histone H2A; Belongs to the histone H2A family. (140 aa)
LOC113579037Histone H2B; Belongs to the histone H2B family. (139 aa)
ENSEEEP00000029755Histone H2A; Belongs to the histone H2A family. (140 aa)
LOC113586889Uncharacterized protein. (102 aa)
Ubn1Ubinuclein 1. (313 aa)
ccne1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (410 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (667 aa)
LOC113576955Histone H2A; Belongs to the histone H2A family. (140 aa)
ENSEEEP00000023877Uncharacterized protein. (753 aa)
LOC113585605Histone H2A; Belongs to the histone H2A family. (129 aa)
pot1Protection of telomeres 1 homolog. (767 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (324 aa)
LOC113571645High mobility group AT-hook 1b. (96 aa)
LOC113567926Uncharacterized protein. (197 aa)
rad50RAD50 homolog, double strand break repair protein. (1181 aa)
LOC113568370Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa)
ENSEEEP00000012861Histone H2B; Belongs to the histone H2B family. (110 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (322 aa)
LOC113578292TINF2_N domain-containing protein. (598 aa)
nbnNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (816 aa)
ENSEEEP00000007003AAA_23 domain-containing protein. (53 aa)
ENSEEEP00000005940Histone H2B; Belongs to the histone H2B family. (131 aa)
LOC113569058AAA_23 domain-containing protein. (469 aa)
LOC113569037Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
HIST1H2BFHistone cluster 1 H2B family member f; Belongs to the histone H2B family. (110 aa)
LOC113568938Histone H2A; Belongs to the histone H2A family. (115 aa)
ENSEEEP00000005177Histone domain-containing protein; Belongs to the histone H2B family. (140 aa)
LOC113568893Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC113568892Histone H2B; Belongs to the histone H2B family. (64 aa)
LOC113583786Histone H2B; Belongs to the histone H2B family. (117 aa)
LOC113572522Uncharacterized protein. (194 aa)
ENSEEEP00000001285Si:ch73-313l22.2. (599 aa)
ENSEEEP00000000760Histone H2B; Belongs to the histone H2B family. (115 aa)
LOC113573654Uncharacterized protein. (206 aa)
LOC113569455Histone H2B; Belongs to the histone H2B family. (67 aa)
ENSEEEP00000000649Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa)
ENSEEEP00000000319Histone domain-containing protein; Belongs to the histone H2B family. (104 aa)
Your Current Organism:
Electrophorus electricus
NCBI taxonomy Id: 8005
Other names: E. electricus, electric eel, electric knifefish
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